Decoding protein persulfidation signaling

Información del proyecto

SULFAGING

Identificador del acuerdo de subvención: 864921

DOI 10.3030/864921

Fecha de la firma de la CE 23 Junio 2020

Fecha de inicio 1 Octubre 2020

Fecha de finalización 30 Septiembre 2026

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total € 1 999 905,00

Aportación de la UE € 1 999 905,00

Coordinado por

LEIBNIZ-INSTITUT FUR ANALYTISCHE WISSENSCHAFTEN-ISAS-EV
Germany

Resultado final

Open Research Data Pilot (1)

Data Management Plan

The DMP provides an analysis of the main elements of the data management policy .

Publicaciones

Peer reviewed articles (6)

The Role of Protein Persulfidation in Brain Aging and Neurodegeneration

Autores: Dunja Petrovic, Emilia Kouroussis, Thibaut Vignane, Milos R. Filipovic
Publicado en: Frontiers in Aging Neuroscience, Edición 13, 2021, ISSN 1663-4365
Editor: Frontiers Research Foundation
DOI: 10.3389/fnagi.2021.674135

Hypoxia sensing requires H2S dependent persulfidation of olfactory receptor 78

Autores: Ying-Jie Peng, Jayasri Nanduri, Ning Wang, Ganesh K. Kumar, Vytautas Bindokas,Bindu D. Paul, Xuanmao Chen, Aaron P. Fox, Thibaut Vignane, Milos R. Filipovic, Nanduri R. Prabhakar
Publicado en: Science Advances, Edición 9(27), 2023, ISSN 2375-2548
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciadv.adf3026

Hydrogen sulfide is neuroprotective in Alzheimer’s disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation

Autores: Daniel Giovinazzo, Biljana Bursac, Juan I. Sbodio, Sumedha Nalluru, Thibaut Vignane, Adele M. Snowman, Lauren M. Albacarys, Thomas W. Sedlak, Roberta Torregrossa, Matthew Whiteman, Milos R. Filipovic, Solomon H. Snyder, Bindu D. Paul
Publicado en: Proceedings of the National Academy of Sciences, Edición 118/4, 2021, Página(s) e2017225118, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2017225118

ATF-4 and hydrogen sulfide signalling mediate longevity in response to inhibition of translation or mTORC1.

Autores: Cyril Statzer, Jin Meng, Richard Venz, Monet Bland, Stacey Robida-Stubbs, Krina Patel, Dunja Petrovic, Raffaella Emsley, Pengpeng Liu, Ianessa Morantte, Cole Haynes, William B. Mair, Alban Longchamp, Milos R. Filipovic, T. Keith Blackwell & Collin Y. Ewald
Publicado en: Nature Communications, Edición 13, 967 (2022), 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-28599-9

Emerging Chemical Biology of Protein Persulfidation

Autores: Thibaut Vignane, Milos R. Filipovic
Publicado en: Antioxidants & Redox Signaling, Edición 39(1-3), 2023, Página(s) 19-39, ISSN 1523-0864
Editor: Mary Ann Liebert Inc.
DOI: 10.1089/ars.2023.0352

Persulfidation protects from oxidative stress under nonphotorespiratory conditions in Arabidopsis

Autores: Margarita García-Calderón, Thibaut Vignane, Milos R. Filipovic, M. Teresa Ruiz, Luis C. Romero, Antonio J. Márquez, Cecilia Gotor, Angeles Aroca
Publicado en: New Phytologist, 2023, ISSN 0028-646X
Editor: Blackwell Publishing Inc.
DOI: 10.1111/nph.18838

Other (1)

Protein thiol alterations drive aberrant phase separation in aging

Autores: Thibaut Vignane, Martín Hugo, Christian Hoffmann, Antionia Katsouda, Jovan Petric, Han Wang, Marko Miler, Ferran Comas, Dunja Petrovic, Suyuan Chen, Jan Lj. Miljkovic, Jordan L Morris, Suvagata Roy Chowdhury, Julien Prudent, Natalija Polovic, Michael P. Murphy, Andreas Papapetropoulos, Dragomir Milovanovic, Milos R. Filipovic
Publicado en: bioRxiv preprint, 2023
Editor: Cold Spring Harbor Laboratory (CSHL)
DOI: 10.1101/2023.11.07.566021

Book chapters (1)

Detection of protein persulfidation in plants by the dimedone switch method

Autores: Angeles Aroca; Ana Jurado-Flores; Milos R. Filipovic; Cecilia Gotor; Luis C. Romero
Publicado en: Methods in Enzymology, Edición 676, 2022, Página(s) 385-402, ISBN 9780323955614
Editor: Academic Press
DOI: 10.1016/bs.mie.2022.07.024