Mechanisms of Microglia Synapse Communication

Información del proyecto

MicroSynCom

Identificador del acuerdo de subvención: 865618

DOI

10.3030/865618

Fecha de la firma de la CE 25 Febrero 2020

Fecha de inicio 1 Septiembre 2020

Fecha de finalización 31 Agosto 2026

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 687 476,00

Aportación de la UE

€ 1 687 476,00

Coordinado por

DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV
Germany

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (12)

Aberrant hippocampal Ca2+ micro-waves following synapsin-dependent adenoviral expression of Ca2+ indicators

Autores: Nicola Masala, Manuel Mittag, Eleonora Ambrad Giovannetti, Darik A. O’Neil, Fabian Distler, Peter Rupprecht, Fritjof Helmchen, Rafael Yuste, Martin Fuhrmann, Heinz Beck, Michael Wenzel, Tony Kelly
Publicado en: eLife, 2024, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.93804.1

Next generation genetically encoded fluorescent sensors for serotonin

Autores: Martin Kubitschke, Monika Müller, Lutz Wallhorn, Mauro Pulin, Manuel Mittag, Stefan Pollok, Tim Ziebarth, Svenja Bremshey, Jill Gerdey, Kristin Carolin Claussen, Kim Renken, Juliana Groß, Pascal Gneiße, Niklas Meyer, J. Simon Wiegert, Andreas Reiner, Martin Fuhrmann & Olivia Andrea Masseck
Publicado en: Nature Communications, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-35200-w

O-LM interneurons: Gatekeepers of pyramidal neuron activity in the hippocampus

Autores: Stefanie Poll, Martin Fuhrmann
Publicado en: Neuron, 2022, ISSN 1097-4199
Editor: Elsevier
DOI: 10.1016/j.neuron.2022.04.022

Memory trace interference impairs recall in a mouse model of Alzheimer's disease.

Autores: Stefanie Poll, Manuel Mittag; Musacchio, F.* ; Justus, L. C.* ; Giovannetti, E. A.* ; Steffen, J.* ; Wagner, J.* ; Zohren, L. ; Schoch, S. ; Schmidt, B. ; Jackson, W. S.* ; Ehninger, D.* ; Martin Fuhrmann (Last author)
Publicado en: Nature Neuroscience, 2020, ISSN 1097-6256
Editor: Nature Publishing Group
DOI: 10.1038/s41593-020-0652-4

Microglial motility is modulated by neuronal activity and correlates with dendritic spine plasticity in the hippocampus of awake mice

Autores: Felix Nebeling; Stefanie Poll; Lena C Justus;Julia Steffen; Kevin Keppler; Manuel Mittag; Martin Fuhrmann (Last author)
Publicado en: eLIFE, 2023, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.83176

Super-Resolution Microscopy Opens New Doors to Life at the Nanoscale

Autores: Martin Fuhrmann, Nala Gockel, Misa Arizono, Yulia Dembitskaya, U Valentin Nägerl, Francesca Pennacchietti, Martina Damenti, Ilaria Testa, Katrin I Willig
Publicado en: Journal of Neuroscience, 2022, ISSN 1529-2401
Editor: Society for Neuroscience
DOI: 10.1523/jneurosci.1125-22.2022

Hippocampal hyperactivity in a rat model of Alzheimer’s disease

Autores: Liudmila Sosulina, Manuel Mittag, Hans-Rüdiger Geis, Kerstin Hoffmann, Igor Klyubin, Yingjie Qi, Julia Steffen, Detlef Friedrichs, Niklas Henneberg, Falko Fuhrmann, Daniel Justus, Kevin Keppler, A. Claudio Cuello, Michael J. Rowan, Martin Fuhrmann, Stefan Remy
Publicado en: Journal of Neurochemistry, 2021, ISSN 1471-4159
Editor: International Society of Neurochemistry
DOI: 10.1111/jnc.15323

Dual truncation of tau by caspase-2 accelerates its CHIP-mediated degradation

Autores: Lydia Reinhardt, Fabrizio Musacchio, Maria Bichmann, Annika Behrendt, Ebru Ercan-Herbst, Juliane Stein, Isabelle Becher, Per Haberkant, Julia Mader, David C. Schöndorf, Melanie Schmitt, Jürgen Korffmann, Peter Reinhardt, Christian Pohl, Mikhail Savitski, Corinna Klein, Laura Gasparini, Martin Fuhrmann, Dagmar E. Ehrnhoefer
Publicado en: Neurobiology of Disease, Edición 182, 2023, Página(s) 106126, ISSN 0969-9961
Editor: Academic Press
DOI: 10.1016/j.nbd.2023.106126

Tracking changes in functionality and morphology of repopulated microglia in young and old mice

Autores: Zuzanna M. Luczak-Sobotkowska, Patrycja Rosa, Maria Banqueri Lopez, Natalia Ochocka, Anna Kiryk, Anna M. Lenkiewicz, Martin Furhmann, Aleksander Jankowski, Bozena Kaminska
Publicado en: Journal of Neuroinflammation, 2024, ISSN 1742-2094
Editor: BioMed Central
DOI: 10.1101/2024.07.12.603244

Elevated expression of complement C4 in the mouse prefrontal cortex causes schizophrenia-associated phenotypes

Autores: Mélanie Druart, Marika Nosten-Bertrand, Stefanie Poll, Sophie Crux, Felix Nebeling, Célia Delhaye, Yaëlle Dubois, Manuel Mittag, Marion Leboyer, Ryad Tamouza, Martin Fuhrmann, Corentin Le Magueresse
Publicado en: Molecular Psychiatry, 2021, ISSN 1359-4184
Editor: Nature Publishing Group
DOI: 10.1038/s41380-021-01081-6

Loss of Ryanodine Receptor 2 impairs neuronal activity-dependent remodeling of dendritic spines and triggers compensatory neuronal hyperexcitability

Autores: Fabio Bertan, Lena Wischhof, Liudmila Sosulina, Manuel Mittag, Dennis Dalügge, Alessandra Fornarelli, Fabrizio Gardoni, Elena Marcello, Monica Di Luca, Martin Fuhrmann, Stefan Remy, Daniele Bano, Pierluigi Nicotera
Publicado en: Cell Death and Differentiation, 2020, ISSN 1476-5403
Editor: Nature Publishing Group
DOI: 10.1038/s41418-020-0584-2

Minocycline treatment improves cognitive and functional plasticity in a preclinical mouse model of major depressive disorder

Autores: Poggini, S. ; Lopez, M. B. ; Albanese, N. C. ; Golia, M. T. ; Ibáñez, F. G. ; Limatola, C. ; Martin Fuhrmann ; Lalowski, M. ; Tremblay, M.-E. ; Maggi, L. ; Kaminska, B. ; Branchi, I.
Publicado en: Behavioral Brain Research, 2023, ISSN 0166-4328
Editor: Elsevier BV
DOI: 10.1016/j.bbr.2023.114295

Other (8)

Deficiency of actin depolymerizing factors ADF/Cfl1 in microglia decreases motility and impairs memory

Autores: Sophie Crux, Marie Denise Roggan, Stefanie Poll, Felix C. Nebeling, Juliane Schiweck, Manuel Mittag, Fabrizio Musacchio, Julia Steffen, Katharina M. Wolff, Andrea Baral, Walter Witke, Christine Gurniak, Frank Bradke, Martin Fuhrmann
Publicado en: bioRxiv, 2024
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.09.27.615114

Microglia motility depends on neuronal activity and promotes structural plasticity in the hippocampus

Autores: Felix C. Nebeling, Stefanie Poll, Lena C. Schmid, Manuel Mittag, Julia Steffen, Kevin Keppler, Martin Fuhrmann
Publicado en: bioRxiv, 2020
Editor: CSHL
DOI: 10.1101/515759

PinkyCaMP a mScarlet-based calcium sensor with exceptional brightness, photostability, and multiplexing capabilities

Autores: Ryan Fink, Shosei Imai, Nala Gockel, German Lauer, Kim Renken, Jonas Wietek, Paul J. Lamothe-Molina, Falko Fuhrmann, Manuel Mittag, Tim Ziebarth, Annika Canziani, Martin Kubitschke, Vivien Kistmacher, Anny Kretschmer, Eva Sebastian, Dietmar Schmitz, Takuya Terai, Jan Gründemann, Sami Hassan, Tommaso Patriarchi, Andreas Reiner, Martin Fuhrmann, Robert E. Campbell, Olivia Andrea Masseck
Publicado en: bioRxiv, 2025
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.12.16.628673

Dynamics of microglia-glioblastoma crosstalk at the far infiltration zone

Autores: Felix C. Nebeling, Falko Fuhrmann, Manuel Mittag, Fabrizio Musacchio, Nala E. Gockel, Lea L. Friker, Sonia Leonardelli, Severin Filser, A Deli, Miriam Stork, Daniele Bano, Torsten Pietsch, Simona Parrinello, Michael Hoelzel, Ulrich Herrlinger, Paolo Salomoni, Martin Fuhrmann
Publicado en: bioRxiv, 2024
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.09.23.614016

Three-photon in vivo imaging of neurons and glia in the medial prefrontal cortex with sub-cellular resolution

Autores: Falko Fuhrmann, Felix C. Nebeling, Fabrizio Musacchio, Manuel Mittag, Stefanie Poll, Monika Müller, Eleonora Ambrad Giovannetti, Michael Maibach, Barbara Schaffran, Emily Burnside, Ivy Chi Wai Chan, Alex Simon Lagurin, Nicole Reichenbach, Sanjeev Kaushalya, Hans Fried, Stefan Linden, Gabor C. Petzold, Gaia Tavosanis, Frank Bradke, Martin Fuhrmann
Publicado en: bioRxiv, 2024
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.08.28.610026

CX3CR1 modulates migration of resident microglia towards brain injury

Autores: Jens Wagner, Cornelia Hoyer, Henrike Antony, Kristiina Lundgrén, Rabah Soliymani, Sophie Crux, Lena Justus, Kevin Keppler, Julia Steffen, Christian Kurts, Daniel R. Engel, Jochen Herms, Maciej Łałowski, Martin Fuhrmann
Publicado en: bioRxiv, 2024
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.09.23.614458

sDarken: Next generation genetically encoded fluorescent sensors for serotonin

Autores: Martin Kubitschke, Monika Müller, Lutz Wallhorn,Mauro Pulin, Manuel Mittag, Stefan Pollok, Tim Ziebarth, Svenja Bremshey, Jill Gerdey, Kristin Carolin Claussen, Kim Renken, Juliana Groß, Niklas Meyer, Simon Wiegert, Andreas Reiner, Martin Fuhrmann, Olivia Andrea Masseck
Publicado en: bioRxiv, 2022
Editor: bioRxiv
DOI: 10.1101/2022.03.10.483799

The Diagonal Band of Broca Regulates Olfactory-Mediated Behaviors by Modulating Odor-Evoked Responses Within the Olfactory Bulb

Autores: Inna Schwarz, Monika Müller, Irina Pavlova, Jens Schweihoff, Fabrizio Musacchio, Manuel Mittag, Martin Fuhrmann, Martin K. Schwarz
Publicado en: bioRxiv, 2021
Editor: bioRxiv
DOI: 10.2139/ssrn.3927424