Cellular control of membrane protein density in the endoplasmic reticulum via the unfolded protein response

Información del proyecto

MemDense

Identificador del acuerdo de subvención: 866011

DOI 10.3030/866011

Fecha de la firma de la CE 19 Diciembre 2019

Fecha de inicio 1 Abril 2020

Fecha de finalización 31 Marzo 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total € 1 934 065,00

Aportación de la UE € 1 934 065,00

Coordinado por

UNIVERSITAT DES SAARLANDES
Germany

Resultado final

Open Research Data Pilot (1)

Data Management Plan (DMP)

Data Management Plan DMP

Publicaciones

Peer reviewed articles (5)

A Quantitative Analysis of Cellular Lipid Compositions During Acute Proteotoxic ER Stress Reveals Specificity in the Production of Asymmetric Lipids

Autores: John Reinhard, Carsten Mattes, Kristina Väth, Toni Radanović, Michal A. Surma, Christian Klose, Robert Ernst
Publicado en: Frontiers in Cell and Developmental Biology, Edición 8, 2020, Página(s) 756, ISSN 2296-634X
Editor: Frontiers
DOI: 10.3389/fcell.2020.00756

Remodeling of yeast vacuole membrane lipidomes from the log (one phase) to stationary stage (two phases)

Autores: John Reinhard, Chantelle L Leveille, Caitlin E Cornell, Alexey J Merz, Christian Klose, Robert Ernst, Sarah L Keller
Publicado en: Biophysical Journal, Edición 122/6, 2023, Página(s) 1043-1057, ISSN 0006-3495
Editor: Biophysical Society
DOI: 10.1016/j.bpj.2023.01.009

The Unfolded Protein Response as a Guardian of the Secretory Pathway

Autores: Toni Radanović, Robert Ernst
Publicado en: Cells, Edición 10/11, 2021, Página(s) 2965, ISSN 2073-4409
Editor: MDPI
DOI: 10.3390/cells10112965

Cysteine cross-linking in native membranes establishes the transmembrane architecture of Ire1

Autores: Kristina Väth, Carsten Mattes, John Reinhard, Roberto Covino, Heike Stumpf, Gerhard Hummer, Robert Ernst
Publicado en: Journal of Cell Biology, Edición 220/8, 2021, Página(s) e202011078, ISSN 0021-9525
Editor: Rockefeller University Press
DOI: 10.1083/jcb.202011078

Systematic analysis of membrane contact sites in Saccharomyces cerevisiae uncovers modulators of cellular lipid distribution

Autores: Inês Gomes Castro, Shawn P Shortill, Samantha Katarzyna Dziurdzik, Angela Cadou, Suriakarthiga Ganesan, Rosario Valenti, Yotam David, Michael Davey, Carsten Mattes, Ffion B Thomas, Reut Ester Avraham, Hadar Meyer, Amir Fadel, Emma J Fenech, Robert Ernst, Vanina Zaremberg, Tim P Levine, Christopher Stefan, Elizabeth Conibear, Maya Schuldiner
Publicado en: eLife, Edición 2050084X, 2022, Página(s) 74602, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.74602

Other (2)

A new technology for isolating organellar membranes provides fingerprints of lipid bilayer stress

Autores: John Reinhard, Leonhard Starke, Christian Klose, Per Haberkant, Henrik Hammarén, Frank Stein, Ofir Klein, Charlotte Berhorst, Heike Stumpf, James P. Sáenz, Jochen Hub, Maya Schuldiner, Robert Ernst
Publicado en: bioRxiv, 2022
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.09.15.508072

Remodeling of yeast vacuole membrane lipidomes from the log (1-phase) to stationary stage (2-phases)

Autores: John Reinhard, Chantelle L. Leveille, Caitlin E. Cornell, Alexey J. Merz, Robert Ernst, Sarah L. Keller
Publicado en: bioRxiv, 2022
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.10.11.511736