Overlaid Transcriptional and Proteome Analyses Identify Mitotic Kinesins as Important Targets of Arylsulfonamide-Mediated RBM39 Degradation
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Autores:
Seemon Coomar;
Pedro Mota;
Alexander Penson;
Jürg Schwaller;
Omar Abdel-Wahab;
Dennis Gillingham
Publicado en:
Molecular Cancer Research, 2023, ISSN 1541-7786
Editor:
American Association for Cancer Research
DOI:
10.1158/1541-7786.mcr-22-0541
Repurposing the Damage Repair Protein Methyl Guanine Methyl Transferase as a Ligand Inducible Fusion Degron
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Autores:
Gosia M. Murawska, Caspar Vogel, Max Jan, Xinyan Lu, Matthias Schild, Mikolaj Slabicki, Charles Zou, Saule Zhanybekova, Manisha Manojkumar, Georg Petzold, Peter Kaiser, Nicolas Thomä, Benjamin Ebert, and Dennis Gillingham
Publicado en:
ACS Chemical Biology, Edición not yet known, 2022, Página(s) not yet known, ISSN 1554-8929
Editor:
American Chemical Society
DOI:
10.1021/acschembio.1c00771
A high affinity pan-PI3K binding module supports selective targeted protein degradation of PI3Kα
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Autores:
Werner Theodor Jauslin, Matthias Schild, Thorsten Schaefer, Chiara Borsari, Clara Orbegozo, Lukas Bissegger, Saule Zhanybekova, Danilo Ritz, Alexander Schmidt, Matthias Wymann, Dennis Gillingham
Publicado en:
Chemical Science, Edición 15, 2024, Página(s) 683-691, ISSN 2041-6520
Editor:
Royal Society of Chemistry
DOI:
10.1039/d3sc04629j
