Project description
A mouse model for drug toxicology studies
Nearly 7 in 10 drugs under development fail due to toxicity or issues in metabolism and excretion. Current drug testing models do not faithfully recapitulate human liver physiology and are thus unsuitable for predicting the safety of drugs destined for human use. To address this problem, the EU-funded His-Li mouse project is developing a humanised mouse model that is suitable for preclinical drug testing. The His-Li mouse offers humanised liver and immune system function, allowing for more faithful results regarding drug safety. Following the feasibility study, the project will formulate a marking and supply strategy to introduce the His-Li mouse model into the pharmaceutical industry.
Fields of science
- medical and health sciencesbasic medicinepharmacology and pharmacydrug discovery
- medical and health sciencesclinical medicinegastroenterologyinflammatory bowel disease
- medical and health sciencesbasic medicineimmunology
- medical and health scienceshealth sciencesinfectious diseasesRNA virusescoronaviruses
- medical and health sciencesclinical medicinecardiologycardiovascular diseases
Programme(s)
Funding Scheme
SME-1 - SME instrument phase 1Coordinator
TRANSCURE BIOSERVICES SAS
Net EU contribution
€ 50 000,00
Address
Biopark Le Forum 1 260 Avenue Mari
74160 Arachamps
France
74160 Arachamps
France
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Region
Auvergne-Rhône-Alpes Rhône-Alpes Haute-Savoie
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 21 429,00