Non-biased fluorescent dyes as markers of drugs for optical in cellulo and in vivo imaging

Informazioni relative al progetto

NoBiasFluors

ID dell’accordo di sovvenzione: 872331

DOI

10.3030/872331

Progetto chiuso

Data della firma CE 23 Ottobre 2019

Data di avvio 1 Gennaio 2020

Data di completamento 31 Dicembre 2024

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 699 200,00

Contributo UE

€ 671 600,00

Coordinato da

FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (2)

NoBiasFluors Newsletter 1
NoBiasFluors Newsletter 2

Other (1)

Set-up of NoBiasFluors web page including the design of consortium’s Logo

Set-up of NoBiasFluors web page including the design of consortium’s Logo

Pubblicazioni

Peer reviewed articles (21)

Synthesis, Antiproliferative Activity, and DNA Binding Studies of Nucleoamino Acid-Containing Pt(II) Complexes

Autori: Claudia Riccardi, Domenica Capasso, Angela Coppola, Chiara Platella, Daniela Montesarchio, Sonia Di Gaetano, Giovanni N. Roviello, Domenica Musumeci
Pubblicato in: Pharmaceuticals, Numero 13/10, 2020, Pagina/e 284, ISSN 1424-8247
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ph13100284

Photophysical Characterization and Biointeractions of NIR Squaraine Dyes for in Vitro and in Vivo Bioimaging

Autori: Sai Kiran Mavileti, Galyna Bila, Valentyn Utka, Evgenia Bila, Tamaki Kato, Rostyslav Bilyy, Shyam S. Pandey
Pubblicato in: ACS Applied Bio Materials, Numero 7, 2024, Pagina/e 416-428, ISSN 2576-6422
Editore: ACS Applied Bio Materials
DOI: 10.1021/acsabm.3c00997

SYNTHESIS OF NOVEL ALDEHYDES SUITABLE FOR BIOCONJUGATION BY INTRODACTION OF A CARBOXYL GROUP VIA ALKYLATION OF HYDROXYBENZALDEHYDES WITH CHLOROACETIC ACID

Autori: Natalia M. Fedosova, Victor Ya. Chernii, Iryna M. Tretyakova, Vladyslava B. Kovalska, Victor Ciornea, Alexandru Rotaru
Pubblicato in: ACTA CHEMICA IASI, Numero 32, 2024, Pagina/e 73-84, ISSN 2067-2446
Editore: Editura Universitatii Alexandru Ioan Cuza din Iasi
DOI: 10.47743/achi-2024-1-0005

A biocompatible NIR squaraine dye and dye-antibody conjugates for versatile long-term <i>in vivo</i> fluorescence bioimaging

Autori: null Priyanka, Galyna Bila, Sai Kiran Mavileti, Evgenia Bila, Nazar Negrych, Shekhar Gupta, Linjun Tang, Rostyslav Bilyy, Shyam S. Pandey, Tamaki Kato
Pubblicato in: Materials Advances, Numero 5, 2024, Pagina/e 3940-3949, ISSN 2633-5409
Editore: The Royal Society of Chemistry
DOI: 10.1039/d4ma00212a

The synthesis and study of novel merocyanine probes for protein detection and cells visualization

Autori: A. Syniugina, S. Chernii, M. Losytskyy, A. Syniugin, Yu. Slominskii, A. Balanda, H.G. Özkan, A. Mokhir, V. Kovalska, S. Yarmoluk
Pubblicato in: Journal of Photochemistry and Photobiology, Numero 7, 2021, Pagina/e 100046, ISSN 2666-4690
Editore: Elsevier BV
DOI: 10.1016/j.jpap.2021.100046

Far-red pentamethine cyanine dyes as fluorescent probes for the detection of serum albumins

Autori: D. Aristova, G. Volynets, S. Chernii, M. Losytskyy, A. Balanda, Yu. Slominskii, A. Mokhir, S. Yarmoluk, V. Kovalska
Pubblicato in: Royal Society Open Science, Numero 7, 2021, Pagina/e 200453, ISSN 2054-5703
Editore: The Royal Society Publishing
DOI: 10.1098/rsos.200453

Nucleic Acid Probes in Bio-Imaging and Diagnostics: Recent Advances in ODN-Based Fluorescent and Surface-Enhanced Raman Scattering Nanoparticle and Nanostructured Systems

Autori: Monica-Cornelia Sardaru, Narcisa-Laura Marangoci, Rosanna Palumbo, Giovanni N. Roviello, Alexandru Rotaru
Pubblicato in: Molecules, Numero 28, 2023, Pagina/e 3561, ISSN 1420-3049
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules28083561

Monomethine cyanine probes for visualization of cellular RNA by fluorescence microscopy

Autori: Daria Aristova, Viktoriia Kosach, Svitlana Chernii, Yuriy Slominsky, Anatoliy Balanda, Valeriy Filonenko, Sergiy Yarmoluk, Alexandru Rotaru, Hülya Gizem Özkan, Andriy Mokhir
Pubblicato in: Methods and Applications in Fluorescence, Numero 9 / 13 July 2021, 2021, Pagina/e 045002, ISSN 2050-6120
Editore: IOPSCIENCE
DOI: 10.1088/2050-6120/ac10ad

Synthesis and Photophysical Properties of Indolenine Styrylcyanine Dye and its Carboxyl-Labeled Derivative

Autori: Chernii
Pubblicato in: Biointerface Research in Applied Chemistry, Numero 13, 2025, Pagina/e 502, ISSN 2069-5837
Editore: AMG Transcend Association
DOI: 10.33263/briac136.502

Injectable Thixotropic β–Cyclodextrin–Functionalized Hydrogels Based on Guanosine Quartet Assembly

Autori: Monica-Cornelia Sardaru, Irina Rosca, Simona Morariu, Elena-Laura Ursu, Razvan Ghiarasim, Alexandru Rotaru
Pubblicato in: International Journal of Molecular Sciences, 2021, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22179179

ENZYMATIC OXIDATION OF THIAZOLIDINES IN THE PRESENCE OF CYCLODEXTRINS: EVALUATION OF ANTIMICROBIAL ACTIVITY OF THE REACTANTS AND PRODUCTS

Autori: Volodymyr O. Antonyuk, Nazar O. Manko, Lidiia V. Panchak, Rostyslav O. Bilyy, Halina I. Bila, Lidiia Ya. Antonyuk, Razvan Ghiarasim, Alexandru V. Rotaru, Roman B. Lesyk
Pubblicato in: ACTA CHEMICA IASI, Numero 32, 2025, Pagina/e 101-118, ISSN 2067-2446
Editore: ALEXANDRU IOAN CUZA UNIVERSITY OF IASI
DOI: 10.47743/achi-2024-2-0007

Spectroscopic and In Silico Studies on the Interaction of Substituted Pyrazolo[1,2-a]benzo[1,2,3,4]tetrazine-3-one Derivatives with c-Myc G4-DNA

Autori: Mulliri S, Laaksonen A, Spanu P, Farris R, Farci M, Mingoia F, Roviello GN, Mocci F
Pubblicato in: International Journal Of Molecular Sciences, 2021, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22116028

Photothermal Hydrogel Composites Featuring G4-Carbon Nanomaterial Networks for <i>Staphylococcus aureus</i> Inhibition

Autori: Monica-Cornelia Sardaru, Irina Rosca, Cristian Ursu, Ioan-Andrei Dascalu, Elena-Laura Ursu, Simona Morariu, Alexandru Rotaru
Pubblicato in: ACS Omega, Numero 9, 2024, Pagina/e 15833-15844, ISSN 2470-1343
Editore: ACS Omega
DOI: 10.1021/acsomega.3c07724

Neutrophils as Main Players of Immune Response towards Nondegradable Nanoparticles

Autori: Rostyslav Bilyy, Galyna Bila, Oleg Vishchur, Volodymyr Vovk, Martin Herrmann
Pubblicato in: Nanomaterials, Numero 10/7, 2020, Pagina/e 1273, ISSN 2079-4991
Editore: MDPI
DOI: 10.3390/nano10071273

3D-Shaped Binders of Unfolded Proteins Inducing Cancer Cell-Specific Endoplasmic Reticulum Stress In Vitro and In Vivo

Autori: Insa Klemt, Oleg Varzatskii, Roman Selin, Serhii Vakarov, Vladyslava Kovalska, Galyna Bila, Rostyslav Bilyy, Yan Voloshin, Itziar Cossío Cuartero, Andrés Hidalgo, Benjamin Frey, Ina Becker, Bernhard Friedrich, Rainer Tietze, Ralf P. Friedrich, Christoph Alexiou, Elena-Laura Ursu, Alexandru Rotaru, Iris Solymosi, M. Eugenia Pérez-Ojeda, Andriy Mokhir
Pubblicato in: Journal of the American Chemical Society, Numero 145, 2023, Pagina/e 22252-22264, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.3c08827

Variation of photostability of DNA-sensitive styrylcyanine dyes caused by N-alkyl functionalization

Autori: Y. V. Snihirova, M. Yu. Losytskyy, D. V. Kryvorotenko, M. V. Kuperman, O. V. Moshynets, S. M. Yarmoluk, A. Mokhir, V. B. Kovalska
Pubblicato in: Biopolymers and Cell, Numero 36, 2020, Pagina/e 146-160, ISSN 0233-7657
Editore: Naukova Dumka
DOI: 10.7124/bc.000a28

Red Fluorescent Aminoferrocene (Pro)Drugs for <i>in Cellulo</i> and <i>in Vivo</i> Imaging

Autori: Svitlana Chernii, Roman Selin, Galyna Bila, Rostyslav Bilyy, Marlies Körber, Andriy Mokhir
Pubblicato in: Chemistry – A European Journal, Numero 30, 2024, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202401107

Squaraine-Peptide Conjugates as Efficient Reporters of Neutrophil Extracellular Traps-Mediated Chronic Inflammation

Autori: Sai Kiran Mavileti, Galyna Bila, Valentyn Utka, Rostyslav Bilyy, Evgenia Bila, Elena Butoi, Shekhar Gupta, Priyanka Balyan, Tamaki Kato, Rostyslav Bilyy, Shyam S. Pandey
Pubblicato in: ACS Applied Materials &amp; Interfaces, Numero 17, 2025, Pagina/e 9140-9154, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/acsami.4c20658

Evidence of protein binding by a nucleopeptide based on a thymine-decorated L-diaminopropanoic acid through CD and in silico studies

Autori: Valentina Roviello, Domenica Musumeci, Andriy Mokhir, Giovanni N. Roviello
Pubblicato in: Current Medicinal Chemistry, Numero 28, 2021, ISSN 0929-8673
Editore: Bentham Science Publishers
DOI: 10.2174/0929867328666210201152326

Cyclodextrin Encapsulated pH Sensitive Dyes as Fluorescent Cellular Probes: Self-Aggregation and In Vitro Assessments

Autori: Monica-Cornelia Sardaru, Oana Carp, Elena-Laura Ursu, Anda-Mihaela Craciun, Corneliu Cojocaru, Mihaela Silion, Vladyslava Kovalska, Ionel Mangalagiu, Ramona Danac, Alexandru Rotaru
Pubblicato in: Molecules, Numero 25/19, 2020, Pagina/e 4397, ISSN 1420-3049
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25194397

N-alkyl functionalized squaraine dyes as fluorescent probes for the detection of serum albumins

Autori: A. T. Syniugina, S. V. Chernii, M. Yu. Losytskyy, H. G. Ozkan, Yu. L. Slominskii, A. R. Syniugin, V. Pekhnyo, A. A. Mokhir, S. M. Yarmoluk
Pubblicato in: Biopolymers and Cell, Numero 38, 2022, Pagina/e 103-116, ISSN 0233-7657
Editore: Naukova Dumka
DOI: 10.7124/bc.000a75

Non-peer reviewed articles (2)

Trimethine Cyanine Dyes as NA-Sensitive Probes for Visualization of Cell Compartments in Fluorescence Microscopy

Autori: Daria Aristova; Roman Selin; Hannah Sophie Heil; Viktoriia Kosach; Yuriy Slominsky; Sergiy Yarmoluk; Vasyl Pekhnyo; Vladyslava Kovalska; Ricardo Henriques; Andriy Mokhir; Svitlana Chernii
Pubblicato in: Crossref, Numero 2, 2022, ISSN 2470-1343
Editore: ACS Omega
DOI: 10.1021/acsomega.2c05231

The Potential of Developing Pan-Coronaviral Antibodies to Spike Peptides in Convalescent COVID-19 Patients.

Autori: Andrii Rabets; Galyna Bila; Roman Grytsko; Markian Samborskyy; Yuriy Rebets; Sandor G. Vari; Quentin Pagneux; Alexandre Barras; Rabah Boukherroub; Sabine Szunerits; Rostyslav Bilyy
Pubblicato in: HAL science ouverte, Numero 1, 2021, ISSN 1661-4917
Editore: Springer
DOI: 10.1007/s00005-021-00607-8

Book chapters (1)

Nano- and Microparticles and Their Role in Inflammation and Immune Response: Focus on Neutrophil Extracellular Traps

Autori: Galyna Bila, Andrii Rabets & Rostyslav Bilyy
Pubblicato in: Biomedical Nanomaterials, 2022, Pagina/e 149-170
Editore: Springer
DOI: 10.1007/978-3-030-76235-3_6

Thesis and dissertations (1)

Mechanisms of selective cancer targeting exploiting distinct hallmarks of cancer cells

Autori: Insa Klemt
Pubblicato in: 2025
Editore: Friedrich-Alexander-Universität Erlangen-Nürnberg