Livrables Documents, reports (11) Developing a morphology-based RNAi-screening assay for the detection of EMT or MET External server set up and access for all RISE-cONCReTE participants Characterizing the roles of ncRNAs involved in EMT Methods for the identification of non-coding RNA modulated by histone modification colon and breast cancer cell lines are used Methods for identification of RNA binders Identify the molecular map of RNA binders and ncRNAs and identify new target for personalized cancer therapies Characterize the role in tumor cell biology of the identified RNA binders ncRNAs ncRNAs involved in hypoxia and, CAIX in glioma Characterize the relationship between ncRNAs, hypoxia and, CAIX in glioma and identification of a non-coding RNA signatures. Characterize the role of ncRNAs regulating hypoxia cascade in tumor cell biology Content for network wide events approved by Director of TOK Appointment of Project Monitor Identification of ncRNAs implicated in exosome-mediated tumor/stroma communication Identification of non coding RNA loci modulated by DNA methylation that could represent novel therapeutical target two sources of human malignancies are used cancer cell lines and primary tumors Gender equality monitoring Publications Peer reviewed articles (40) miR-216a Acts as a Negative Regulator of Breast Cancer by Modulating Stemness Properties and Tumor Microenvironment Auteurs: Giuseppina Roscigno, Assunta Cirella, Alessandra Affinito, Cristina Quintavalle, Iolanda Scognamiglio, Francesco Palma, Francesco Ingenito, Silvia Nuzzo, Francesca De Micco, Antonio Cuccuru, Renato Thomas, Gerolama Condorelli Publié dans: International Journal of Molecular Sciences, Issue 21/7, 2020, Page(s) 2313, ISSN 1422-0067 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms21072313 Practical tips and new trends in electrochemical biosensing of cancer-related extracellular vesicles Auteurs: Patrick Severin Sfragano, Serena Pillozzi, Gerolama Condorelli, Ilaria Palchetti Publié dans: Analytical and bioanalytical chemistry., 2023, Page(s) 1-20, ISSN 1618-2650 Éditeur: Springer DOI: 10.1007/s00216-023-04530-z Exploiting the Natural Properties of Extracellular Vesicles in Targeted Delivery towards Specific Cells and Tissues Auteurs: Pablo Lara, Alan B. Chan, Luis J. Cruz, Andrew F. G. Quest, Marcelo J. Kogan Publié dans: Pharmaceutics, Issue 12/11, 2020, Page(s) 1022, ISSN 1999-4923 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics12111022 Urinary Dickkopf-3 and Contrast-Associated Kidney Damage Auteurs: Giuseppina Roscigno, Cristina Quintavalle, Giuseppe Biondi-Zoccai, Francesca De Micco, Giacomo Frati, Alessandra Affinito, Silvia Nuzzo, Gerolama Condorelli, Carlo Briguori Publié dans: Journal of the American College of Cardiology, Issue 77/21, 2021, Page(s) 2667-2676, ISSN 0735-1097 Éditeur: Elsevier BV DOI: 10.1016/j.jacc.2021.03.330 IL-6/STAT3 signaling in tumor cells restricts the expression of frameshift-derived neoantigens by SMG1 induction Auteurs: Daniel Meraviglia-Crivelli; Helena Villanueva; Angelina Zheleva; María Villalba-Esparza; Beatriz Moreno; Ashwathi Puravankara Menon; Alfonso Calvo; Javier Cebollero; Martin Barainka; Igor Ruiz de los Mozos; Carlos Huesa-Berral; Fernando Pastor Publié dans: Molecular Cancer,, Issue 12, 2022, Page(s) Vol 21, Iss 1, Pp 1-24, ISSN 1476-4598 Éditeur: BioMed Central DOI: 10.1186/s12943-022-01679-6 Zinc-Phthalocyanine-Loaded Extracellular Vesicles Increase Efficacy and Selectivity of Photodynamic Therapy in Co-Culture and Preclinical Models of Colon Cancer Auteurs: Pablo Lara, Ruben V. Huis in ‘t Veld, Carla Jorquera-Cordero, Alan B. Chan, Ferry Ossendorp, Luis J. Cruz Publié dans: Pharmaceutics, Issue 13/10, 2021, Page(s) 1547, ISSN 1999-4923 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics13101547 Overview and Future Perspectives on Tumor-Targeted Positron Emission Tomography and Fluorescence Imaging of Pancreatic Cancer in the Era of Neoadjuvant Therapy Auteurs: Martijn A. van Dam; Floris A. Vuijk; Judith A. Stibbe; Ruben D. Houvast; Saskia A. C. Luelmo; Stijn Crobach; Shirin Shahbazi Feshtali; Lioe-Fee de Geus-Oei; Bert A. Bonsing; Cornelis F. M. Sier; Peter J. K. Kuppen; Rutger-Jan Swijnenburg; Albert D. Windhorst; Jacobus Burggraaf; Alexander L. Vahrmeijer; J. Sven D. Mieog Publié dans: Cancers, Issue 13, 2021, Page(s) 13(23), ISSN 2072-6694 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers13236088 Effect of the Addition of Alginate and/or Tetracycline on Brushite Cement Properties Auteurs: Claudia Morilla, Elianis Perdomo, Ana Karla Hernández, Ramcy Regalado, Amisel Almirall, Gastón Fuentes, Yaima Campos Mora, Timo Schomann, Alan Chan, Luis J. Cruz Publié dans: Molecules, Issue 26/11, 2021, Page(s) 3272, ISSN 1420-3049 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/molecules26113272 Introducing Fluorescence-Guided Surgery for Pediatric Ewing, Osteo-, and Rhabdomyosarcomas: A Literature Review Auteurs: Rijs, Z.; Jeremiasse, B.; Shifai, N.; Gelderblom, H.; Sier, C.F.M.; Vahrmeijer, A.L.; Leeuwen, F.W.B. van; Steeg, A.F.W. van der; Sande, M.A.J. van de Publié dans: Biomedicines, Issue 9, 2021, Page(s) VOLUME=9;ISSUE=10, ISSN 2227-9059 Éditeur: MDPI DOI: 10.3390/biomedicines9101388 Extracellular Vesicles from M1-Polarized Macrophages Combined with Hyaluronic Acid and a β-Blocker Potentiate Doxorubicin’s Antitumor Activity by Downregulating Tumor-Associated Macrophages in Breast Cancer Auteurs: Carla Jorquera-Cordero, Pablo Lara , Luis J Cruz , Timo Schomann , Anna van Hofslot, Thaís Gomes de Carvalho , Paulo Marcos Da Matta Guedes, Laura Creemers, Roman I Koning, Alan B Chan, Raimundo Fernandes de Araujo Junior Publié dans: Pharmaceutics, Issue 14(5), 2022, Page(s) 1068, ISSN 1999-4923 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics14051068 Exosomal microRNAs synergistically trigger stromal fibroblasts in breast cancer Auteurs: Iolanda Scognamiglio, Lorenza Cocca, Ilaria Puoti, Francesco Palma, Francesco Ingenito, Cristina Quintavalle, Alessandra Affinito, Giuseppina Roscigno, Silvia Nuzzo, Rosario Vincenzo Chianese, Stefania Belli, Guglielmo Thomas, Timo Schomann, Alan Chan, Maria Patrizia Stoppelli, Gerolama Condorelli Publié dans: Molecular therapy. Nucleic acids, Issue vol. 28, 2022, Page(s) 17-31, ISSN 2162-2531 Éditeur: Nature Publishing Group DOI: 10.1016/j.omtn.2022.02.013 Chemical, Antioxidant, and Antimicrobial Properties of the Peel and Male Flower By-Products of Four Varieties of Punica granatum L. Cultivated in the Marche Region for Their Use in Cosmetic Products Auteurs: Maria Rosa Gigliobianco; Manuela Cortese; Samanta Nannini; Lucrezia Di Nicolantonio; Dolores Vargas Peregrina; Giulio Lupidi; Luca Agostino Vitali; Elena Bocchietto; Piera Di Martino; Roberta Censi Publié dans: Antioxidants, Issue 11, 2022, Page(s) 768, ISSN 2076-3921 Éditeur: Basel, Switzerland DOI: 10.3390/antiox11040768 Prognostic and Clinicopathological Significance of MiR-155 in Breast Cancer: A Systematic Review Auteurs: Anna Maria Grimaldi, Silvia Nuzzo, Gerolama Condorelli, Marco Salvatore, Mariarosaria Incoronato Publié dans: International Journal of Molecular Sciences, Issue 21/16, 2020, Page(s) 5834, ISSN 1422-0067 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms21165834 Ethical implications of epigenetics in the eraof personalized medicine Auteurs: Josep Santaló1 and María Berdasco2,3* Publié dans: Clinical Epigenetics, Issue 14:44, 2022, ISSN 1868-7083 Éditeur: BioMed Central DOI: 10.1186/s13148-022-01263-1 Antifouling Strategies of Nanoparticles for Diagnostic and Therapeutic Application: A Systematic Review of the Literature. Auteurs: Paolo Bevilacqua; Silvia Nuzzo; Enza Torino; Gerolama Condorelli; Marco Salvatore; Anna Maria Grimaldi Publié dans: Nanomaterials, Issue 11, 2021, Page(s) 11(3), 780, ISSN 2079-4991 Éditeur: MDPI DOI: 10.3390/nano11030780 The Incorporation of Etanercept into a Porous Tri-Layer Scaffold for Restoring and Repairing Cartilage Tissue Auteurs: Campos, Yaima; Fuentes, Gastón; Almirall, Amisel; Que, Ivo; Schomann, Timo; Chung, Chih Kit; Jorquera Cordero, Carla; Quintanilla Sierra, Luis; Rodríguez Cabello, José Carlos; Chan, Alan; Cruz, Luis Publié dans: Pharmaceutics, Issue 1, 2022, ISSN 1999-4923 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics14020282 Selection of RNA aptamers targeting hypoxia in cancer Auteurs: Nuzzo S, Iaboni M, Ibba ML, Rienzo A, Musumeci D, Franzese M, Roscigno G, Affinito A, Petrillo G, Quintavalle C, Ciccone G, Esposito CL, Catuogno S Publié dans: Frontiers in molecular biosciences, Issue 2296889X, 2022, ISSN 2296-889X Éditeur: Lausanne : Frontiers Media S.A DOI: 10.3389/fmolb.2022.956935 Gastric Ulcer Healing Property of Bryophyllum pinnatum Leaf Extract in Chronic Model In Vivo and Gastroprotective Activity of Its Major Flavonoid Auteurs: Edilane Rodrigues Dantas De Araújo; Gerlane Coelho Bernardo Guerra; Anderson Wilbur Lopes Andrade; Júlia Morais Fernandes; Valéria Costa Da Silva; Emanuella De Aragão Tavares; Aurigena Antunes De Araújo; Raimundo Fernandes de Araújo Júnior; Raimundo Fernandes de Araújo Júnior; Raimundo Fernandes de Araújo Júnior; Raimundo Fernandes de Araújo Júnior; Silvana Maria Zucolotto; Silvana Ma Publié dans: Frontiers in Pharmacology, Issue 12, 2021, Page(s) Vol 12, ISSN 1663-9812 Éditeur: Frontiers Media S.A. DOI: 10.3389/fphar.2021.744192 Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors Auteurs: Pasquale Russomanno; Giulia Assoni; Giulia Assoni; Jussara Amato; Vincenzo Maria D'Amore; Riccardo Scaglia; Diego Brancaccio; Martina Pedrini; Giovanna Polcaro; Valeria La Pietra; Paolo Orlando; Marianna Falzoni; Linda Cerofolini; Stefano Giuntini; Marco Fragai; Bruno Pagano; Greta Donati; E. Novellino; Cristina Quintavalle; Gerolama Condorelli; Francesco Sabbatino; Pierfausto Seneci; Daniela Aros Publié dans: J. Med. Chem. 2021, 64, 16020−16045, Issue 1, 2021, ISSN 1520-4804 Éditeur: American Chemical Society DOI: 10.1021/acs.jmedchem.1c01409 The Role of RNA and DNA Aptamers in Glioblastoma Diagnosis and Therapy: A Systematic Review of the Literature Auteurs: Silvia Nuzzo, Valentina Brancato, Alessandra Affinito, Marco Salvatore, Carlo Cavaliere, Gerolama Condorelli Publié dans: Cancers, Issue 12/8, 2020, Page(s) 2173, ISSN 2072-6694 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers12082173 Analysis of Differentially Expressed Genes, MMP3 and TESC, and Their Potential Value in Molecular Pathways in Colon Adenocarcinoma: A Bioinformatics Approach Auteurs: Constantin Busuioc; Andreea Nutu; Cornelia Braicu; Oana Zanoaga; Monica Trif; Ioana Berindan-Neagoe Publié dans: BioMedInformatics, Issue 12, 2022, Page(s) 474-491, ISSN 2673-7426 Éditeur: MDPI DOI: 10.3390/biomedinformatics2030030 Combined Targeting of Glioblastoma Stem-Like Cells by Neutralizing RNA-Bio-Drugs for STAT3 Auteurs: Carla Lucia Esposito, Silvia Nuzzo, Maria Luigia Ibba,Lucia Ricci-Vitiani, Roberto Pallini, Gerolama Condorelli,Silvia Catuogno, Vittorio de Franciscis Publié dans: Cancers, Issue 12(6), 2020, Page(s) 1434, ISSN 2072-6694 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers12061434 Combinatorial therapeutic approaches of photodynamic therapy and immune checkpoint blockade for colon cancer treatment Auteurs: Yang Hao, Chih Kit Chung, Zili Gu, Timo Schomann, Xiaoxu Dong, Ruben V Huis In 't Veld, Marcel G M Camps, Peter Ten Dijke, Ferry A Ossendorp, Luis J Cruz Publié dans: Molecular biomedicine, 2022, ISSN 2662-8651 Éditeur: Singapore : Springer Singapore, [2020]- DOI: 10.1186/s43556-022-00086-z Functionalized Nanoparticles Targeting Tumor-Associated Macrophages as Cancer Therapy. Auteurs: Yuanyuan He; Raimundo Fernandes de Araújo Júnior; Luis J. Cruz; Christina Eich Publié dans: Pharmaceutics,, Issue 13(10), 2021, Page(s) 70, ISSN 2078-2489 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics13101670 Identification of a novel RNA aptamer that selectively targets breast cancer exosomes Auteurs: Carla Lucia Esposito, Cristina Quintavalle, Francesco Ingenito, Deborah Rotoli, Giuseppina Roscigno, Silvia Nuzzo, Renato Thomas, Silvia Catuogno, Vittorio de Franciscis, Gerolama Condorelli Publié dans: Molecular Therapy - Nucleic Acids, 2021, ISSN 2162-2531 Éditeur: Nature Publishing Group DOI: 10.1016/j.omtn.2021.01.012 miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer Auteurs: Francesco Palma, Alessandra Affinito, Silvia Nuzzo, Giuseppina Roscigno, Iolanda Scognamiglio, Francesco Ingenito, Lola Martinez, Monica Franzese, Mario Zanfardino, Andrea Soricelli, Alfonso Fiorelli, Gerolama Condorelli, Cristina Quintavalle Publié dans: Cancer Gene Therapy, 2020, ISSN 0929-1903 Éditeur: Nature Publishing Group DOI: 10.1038/s41417-020-00224-1 STAT3 silencing by an aptamer-based strategy hampers the crosstalk between NSCLC cells and cancer-associated fibroblasts Auteurs: Maria L. Ibba,Giuseppe Ciccone,Deborah Rotoli,Gabriele Coppola,Alfonso Fiorelli, Silvia Catuogno,Carla L. Esposito Publié dans: Molecular therapy nucleic acid, Issue 32, 2023, Page(s) 111–126., ISSN 2162-2531 Éditeur: Nature Publishing Group DOI: 10.1016/j.omtn.2023.03.003 Evaluation of EphB4 as Target for Image-Guided Surgery of Breast Cancer Auteurs: Cansu de Muijnck, Yoren van Gorkom, Maurice van Duijvenvoorde, Mina Eghtesadi, Geeske Dekker-Ensink, Shadhvi S. Bhairosingh, Alessandra Affinito, Peter J. K. Kuppen, Alexander L. Vahrmeijer, Cornelis F. M. Sier Publié dans: Pharmaceuticals, Issue 13/8, 2020, Page(s) 172, ISSN 1424-8247 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ph13080172 Nanocarriers as a Tool for the Treatment of Colorectal Cancer Auteurs: Ana Luiza C. de S. L. Oliveira, Timo Schomann, Lioe-Fee de Geus-Oei, Ellen Kapiteijn, Luis J. Cruz, Raimundo Fernandes de Araújo Junior Publié dans: Pharmaceutics, Issue 13/8, 2021, Page(s) 1321, ISSN 1999-4923 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics13081321 Smart Polymeric Micelles for Anticancer Hydrophobic Drugs Auteurs: Guzmán Rodríguez A, Sablón Carrazana M, Rodríguez Tanty C, Malessy MJA, Fuentes G, Cruz LJ. Publié dans: Cancers (Basel), 2022, ISSN 2072-6694 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers15010004 Comparative Proteomic Profiling of Secreted Extracellular Vesicles from Breast Fibroadenoma and Malignant Lesions: A Pilot Study Auteurs: Katia Pane, Cristina Quintavalle, Silvia Nuzzo, Francesco Ingenito, Giuseppina Roscigno, Alessandra Affinito, Iolanda Scognamiglio, Birlipta Pattanayak, Enrico Gallo, Antonella Accardo, Guglielmo Thomas, Zoran Minic, Maxim V Berezovski, Monica Franzese, Gerolama Condorelli Publié dans: International journal of molecular sciences, Issue vol. 23, 2022, ISSN 1422-0067 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms23073989 Thermosensitive Injectable Hydrogels for Intra-Articular Delivery of Etanercept for the Treatment of Osteoarthritis Auteurs: Jomarien García-Couce, Timo Schomann, Chih Kit Chung, Ivo Que, Carla Jorquera-Cordero, Gastón Fuentes, Amisel Almirall, Alan Chan, Luis J Cruz Publié dans: Gels, Issue Quarterly, 2022, ISSN 2310-2861 Éditeur: Basel, Switzerland : MDPI AG, [2015]- DOI: 10.3390/gels8080488 Immunohistochemical Evaluation of Candidate Biomarkers for Fluorescence-Guided Surgery of Myxofibrosarcoma Using an Objective Scoring Method Auteurs: Zeger Rijs; Esther Belt; Gijsbert M. Kalisvaart; Cornelis F. M. Sier; Peter J. K. Kuppen; Arjen H. G. Cleven; Alexander L. Vahrmeijer; Michiel A. J. van de Sande; Pieter B. A. A. van Driel Publié dans: Biomedicines,, Issue 13, 2023, Page(s) Vol 11, Iss 3, p 982, ISSN 2227-9059 Éditeur: MDPI DOI: 10.3390/biomedicines11030982 Impact of the Interactions between Fragrances and Cosmetic Bases on the Fragrance Olfactory Performance: A Tentative to Correlate SPME-GC/MS Analysis with That of an Experienced Perfumer Auteurs: Lucrezia Di Nicolantonio; Maria Rosa Gigliobianco; Dolores Vargas Peregrina; Simone Angeloni; Luca Ilorini; Piera Di Martino; Roberta Censi Publié dans: Cosmetics, Issue 9(4), 2022, Page(s) 70, ISSN 2079-9284 Éditeur: MDPI DOI: 10.3390/cosmetics9040070 The Role of Non-Coding RNAs in Epigenetic Dysregulation in Glioblastoma Development Auteurs: Ekaterina Isachesku, Cornelia Braicu,Radu Pirlog,Anja Kocijancic,Constantin Busuioc,Lavinia-Lorena Pruteanu,Deo Prakash Pandey, Ioana Berindan-Neagoe Publié dans: Int J Mol Sci, Issue 24(22), 2023, Page(s) 16320, ISSN 1422-0067 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms242216320 Bacterial Cellulose as Drug Delivery System for Optimizing Release of Immune Checkpoint Blocking Antibodies Auteurs: Chih Kit Chung; Uwe Beekmann; Dana Kralisch; Katja Bierau; Alan Chan; Ferry Ossendorp; Luis J. Cruz Publié dans: Pharmaceutics, Issue 14, 2022, Page(s) 1351, ISSN 1999-4923 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics14071351 Cell-Based Tracers as Trojan Horses for Image-Guided Surgery Auteurs: Vincent Q. Sier, Margreet R. de Vries, Joost R. van der Vorst, Alexander L. Vahrmeijer, Cornelis van Kooten, Luis J. Cruz, Lioe-Fee de Geus-Oei, Valerie Ferreira, Cornelis F. M. Sier, Frauke Alves, Munitta Muthana Publié dans: International Journal of Molecular Sciences, Issue 22/2, 2021, Page(s) 755, ISSN 1422-0067 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms22020755 Modulating the Crosstalk between the Tumor and the Microenvironment Using SiRNA: A Flexible Strategy for Breast Cancer Treatment Auteurs: Giuseppina Roscigno, Iolanda Scognamiglio, Francesco Ingenito, Rosario Vincenzo Chianese, Francesco Palma, Alan Chan, Gerolama Condorelli Publié dans: Cancers, Issue 12/12, 2020, Page(s) 3744, ISSN 2072-6694 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers12123744 Combinatorial Therapeutic Approaches with Nanomaterial-Based Photodynamic Cancer Therapy Auteurs: Hao, Y.; Chung, C.K.; Yu, Z.F.; Veld, R.H.I.V. 't; Ossendorp, F.A.; Dijke, P. ten; Cruz, L.J. Publié dans: Pharmaceutics, Issue 14 (1), 2022, Page(s) 120, ISSN 2078-2489 Éditeur: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics14010120 Structure‐ and Interaction‐Based Design of Anti‐SARS‐CoV‐2 Aptamers Auteurs: Mironov V, Shchugoreva IA, Artyushenko PV, Morozov D, Borbone N, Oliviero G, Zamay TN, Moryachkov RV, Kolovskaya OS, Lukyanenko KA, Song Y, Merkuleva IA, Zabluda VN, Peters G, Koroleva LS, Veprintsev DV, Glazyrin YE, Volosnikova EA, Belenkaya SV, Esina TI, Isaeva AA, Nesmeyanova VS, Shanshin DV, Berlina AN, Komova NS, Svetlichnyi VA, Silnikov VN, Shcherbakov DN, Zamay GS, Zamay SS, Smolyarova T, T Publié dans: Chemistry, Issue vol 28, 2022, ISSN 0947-6539 Éditeur: John Wiley & Sons Ltd. DOI: 10.1002/chem.202104481 Recherche de données OpenAIRE... Une erreur s’est produite lors de la recherche de données OpenAIRE Aucun résultat disponible
