Descripción del proyecto
Los diagnósticos basados en papel podrían eliminar los obstáculos existentes en las pruebas de campo generalizadas
Los ácidos nucleicos (como el ácido desoxiribonucleico o ADN y el ácido ribonucleico o ARN) están presentes en todas las células y virus. Las pruebas de amplificación del ácido nucleico se utilizan cada vez más para facilitar la detección de ADN o ARN relacionado con bacterias, virus u otros patógenos, incluso cuando está presente en cantidades muy reducidas. Sin embargo, todavía son relativamente complejas y caras para un uso generalizado en los sistemas de diagnóstico inmediato. IPANEMA ha formado una gran red de conocimientos especializados pluridisciplinarios para materializar rápidamente el potencial de las plataformas microfluídicas basadas en papel. Con socios en Europa, los Estados Unidos y terceros países que incluyen pymes e instituciones académicas, IPANEMA trabaja en varias tecnologías distintas que pueden integrarse en teléfonos inteligentes para un diagnóstico inmediato fácil de utilizar y rentable, pero también avanzado.
Objetivo
Twelve-member IPANEMA consortium implements competences of participating academic & industry beneficiaries
and 3rd country partners to 1) create a knowledge/experience-sharing network of scientists, entrepreneurs & endusers
in the multidisciplinary field of biosensors for POCT (point-of care testing); 2) develop innovative bottom-up
approaches for fabrication of low-cost POCT devices & implementation of paper-based nucleic acid testing (NAT);
3) pursue applications in 3 important industry sectors – healthcare, agrifood & environmental monitoring. Research
& Innovation (R&I) activities will be focused on developing low-cost paper-based isothermal NATs, their integration
into microfluidic devices and optimization for use in a) tissue engineering b) agrifood (poultry/plant/fungal) pathogen
detection c) detection of toxigenic freshwater Cyanobacteria causing harmful algal blooms. Secondments & trainings
will enable researchers to acquire both technical & soft skills needed for converting scientific knowledge & ideas
into products & services. Strong involvement of 4 SME partners from Serbia, Israel, France & US contributing their
proprietary knowledge on revolutionary novel materials for microfluidic devices & DNA extraction kits, domain
expertise in agrifood sector, unique portable sensing systems & handheld devices for isoNAT quantification, will help
researchers focus their efforts on development of innovative products for real-life use. Several transducing methods
(colorimetric, fluorescence, SPR, electrochemical, microwave & magnetic) and smartphone-based read-out methods
will be investigated for POCT use. Renowned beneficiaries including academic INRAE, WU, INESC MN, BGU,
UNSPMF & BIOS together with 3rd country academic partners: Columbia University and Xi'an Jiaotong University,
will provide transfer of cutting-edge knowledge and technical expertise in effect yielding good basis for long term
collaboration and joint R&I projects.
Ámbito científico
- natural sciencesphysical sciencesclassical mechanicsfluid mechanicsmicrofluidics
- engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsbiosensors
- engineering and technologyenvironmental biotechnologybiosensing
- natural sciencesbiological sciencesbiochemistrybiomoleculesnucleic acids
- medical and health sciencesmedical biotechnologytissue engineering
Palabras clave
Programa(s)
Régimen de financiación
MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)Coordinador
21000 Novi Sad
Serbia