New-generation cardiac therapeutic strategies directed to the activation of endogenous regenerative mechanisms

Informations projet

REANIMA

N° de convention de subvention: 874764

DOI 10.3030/874764

Date de signature de la CE 12 Decembre 2019

Date de début 1 Janvier 2020

Date de fin 30 Juin 2025

Financé au titre de

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Coût total € 8 000 000,00

Contribution de l’UE € 8 000 000,00

Coordonné par

CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)
Spain

Livrables

Other (2)

Dissemination Kit for conferences and events
Project Website

Documents, reports (1)

A new human in vitro cardiac injury model for the evaluation of endogenous repair mechanisms, cell competition and proproliferative interventions

A new human in vitro cardiac injury model for the evaluation of endogenous repairmechanisms cell competition and proproliferative interventions

Publications

Peer reviewed articles (4)

Transcriptomic data meta-analysis reveals common and injury model specific gene expression changes in the regenerating zebrafish heart

Auteurs: Marius Alexandru Botos; Prateek Arora; Panagiotis Chouvardas; Nadia Mercader
Publié dans: Botos, Marius Alexandru; Arora, Prateek; Chouvardas, Panagiotis; Mercader, Nadia (2023). Transcriptomic data meta-analysis reveals common and injury model specific gene expression changes in the regenerating zebrafish heart. Scientific Reports, 13(1), p. 5418. Nature Publishing Group 10.1038/s41598-023-32272-6 <http://dx.doi.org/10.1038/s41598-023-32272-6>, Numéro 11, 2023, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-023-32272-6

Regulation of endogenous cardiomyocyte proliferation: The known unknowns

Auteurs: Ilaria Secco, Mauro Giacca
Publié dans: Journal of Molecular and Cellular Cardiology, Numéro 179, 2023, Page(s) 80-89, ISSN 0022-2828
Éditeur: Academic Press
DOI: 10.1016/j.yjmcc.2023.04.001

Hypoxia to Stimulate Cardiomyocyte Proliferation After MI? A Word of Caution

Auteurs: Thomas Eschenhagen
Publié dans: Circulation Research, Numéro 132, 2023, Page(s) 741-743, ISSN 0009-7330
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.123.322553

Cardiomyocyte-Specific Wt1 Is Involved in Cardiac Metabolism and Response to Damage

Auteurs: Sandra Díaz del Moral; Maha Benaouicha; Cristina Villa del Campo; Miguel Torres; Nicole Wagner; Kay-Dietrich Wagner; Ramón Muñoz-Chápuli; Rita Carmona
Publié dans: Journal of Cardiovascular Development and Disease, Vol 10, Iss 5, p 211 (2023), Numéro 1, 2023, ISSN 2731-0590
Éditeur: Nature Cardiovascular
DOI: 10.3390/jcdd10050211

Non-peer reviewed articles (2)

Fulfilling the Promise of RNA Therapies for Cardiac Repair and Regeneration

Auteurs: Mauro Giacca
Publié dans: Stem Cells Translational Medicine, Numéro 12(8), 2023, Page(s) 527-535, ISSN 2157-6564
Éditeur: AlphaMed Press
DOI: 10.1093/stcltm/szad038

CRISPR activation and interference as investigative tools in the cardiovascular system

Auteurs: Melissa S. Carroll, Mauro Giacca
Publié dans: The International Journal of Biochemistry & Cell Biology, Numéro 155, 2023, ISSN 1357-2725
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.biocel.2022.106348