New-generation cardiac therapeutic strategies directed to the activation of endogenous regenerative mechanisms

Informazioni relative al progetto

REANIMA

ID dell’accordo di sovvenzione: 874764

DOI 10.3030/874764

Data della firma CE 12 Dicembre 2019

Data di avvio 1 Gennaio 2020

Data di completamento 30 Giugno 2025

Finanziato da

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Costo totale € 8 000 000,00

Contributo UE € 8 000 000,00

Coordinato da

CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)
Spain

Risultati finali

Other (2)

Dissemination Kit for conferences and events
Project Website

Documents, reports (1)

A new human in vitro cardiac injury model for the evaluation of endogenous repair mechanisms, cell competition and proproliferative interventions

A new human in vitro cardiac injury model for the evaluation of endogenous repairmechanisms cell competition and proproliferative interventions

Pubblicazioni

Peer reviewed articles (4)

Transcriptomic data meta-analysis reveals common and injury model specific gene expression changes in the regenerating zebrafish heart

Autori: Marius Alexandru Botos; Prateek Arora; Panagiotis Chouvardas; Nadia Mercader
Pubblicato in: Botos, Marius Alexandru; Arora, Prateek; Chouvardas, Panagiotis; Mercader, Nadia (2023). Transcriptomic data meta-analysis reveals common and injury model specific gene expression changes in the regenerating zebrafish heart. Scientific Reports, 13(1), p. 5418. Nature Publishing Group 10.1038/s41598-023-32272-6 <http://dx.doi.org/10.1038/s41598-023-32272-6>, Numero 11, 2023, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-023-32272-6

Regulation of endogenous cardiomyocyte proliferation: The known unknowns

Autori: Ilaria Secco, Mauro Giacca
Pubblicato in: Journal of Molecular and Cellular Cardiology, Numero 179, 2023, Pagina/e 80-89, ISSN 0022-2828
Editore: Academic Press
DOI: 10.1016/j.yjmcc.2023.04.001

Hypoxia to Stimulate Cardiomyocyte Proliferation After MI? A Word of Caution

Autori: Thomas Eschenhagen
Pubblicato in: Circulation Research, Numero 132, 2023, Pagina/e 741-743, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.123.322553

Cardiomyocyte-Specific Wt1 Is Involved in Cardiac Metabolism and Response to Damage

Autori: Sandra Díaz del Moral; Maha Benaouicha; Cristina Villa del Campo; Miguel Torres; Nicole Wagner; Kay-Dietrich Wagner; Ramón Muñoz-Chápuli; Rita Carmona
Pubblicato in: Journal of Cardiovascular Development and Disease, Vol 10, Iss 5, p 211 (2023), Numero 1, 2023, ISSN 2731-0590
Editore: Nature Cardiovascular
DOI: 10.3390/jcdd10050211

Non-peer reviewed articles (2)

Fulfilling the Promise of RNA Therapies for Cardiac Repair and Regeneration

Autori: Mauro Giacca
Pubblicato in: Stem Cells Translational Medicine, Numero 12(8), 2023, Pagina/e 527-535, ISSN 2157-6564
Editore: AlphaMed Press
DOI: 10.1093/stcltm/szad038

CRISPR activation and interference as investigative tools in the cardiovascular system

Autori: Melissa S. Carroll, Mauro Giacca
Pubblicato in: The International Journal of Biochemistry & Cell Biology, Numero 155, 2023, ISSN 1357-2725
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.biocel.2022.106348