Blue light means stop for rogue neurons sending false pain signals
Anyone living with chronic pain – and about one in every five people do worldwide – can attest to its debilitating physical effects and serious complications, including depression, anxiety and difficulty sleeping, with consequences for personal and professional relationships and even economic stability. Neuropathic pain is chronic pain arising from damaged nerves that send the wrong signals to the brain's pain centres. Nervous signal transmission involves a number of electrical and chemical signals, among which is the inhibitory effect of an influx of potassium ions. The EU-funded BREAK project is targeting potassium channels in neurons with a novel injectable analgesic. Blocking local neurons from signalling pain to the brain could provide relief from neuropathic pain for millions worldwide.
Fields of science
Call for proposalSee other projects for this call
Funding SchemeERC-POC-LS - ERC Proof of Concept Lump Sum Pilot
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