Project description DEENESFRITPL A novel diagnostic imaging system will help ensure transplanted tissue is flourishing Biomedical photoacoustic imaging, also known as optoacoustic imaging, is a relatively new modality gaining increasing interest over the last decade. It combines the high-contrast specificity of optical imaging with the high spatial resolution of ultrasound imaging. In addition, it has greater depth penetration than conventional optical imaging technologies. It can not only visualise microvasculature and haemoglobin structures, but it can also provide functional information on blood oxygenation, blood flow, and temperature. PHOTOPARS is harnessing its potential in a prototype clinical imaging system to evaluate vascularisation of tissue transplants in procedures such as breast reconstruction or burn treatment. Expect improvements in tissue viability, wound healing, and avoidance of infection. Show the project objective Hide the project objective Objective Plastic and reconstructive surgical procedures provide a means of reconstructing tissues following damage due to cancer, trauma, burns and infections. An important example is flap surgery which involves transferring skin and the underlying tissues from one part of the body to another; for example, in the DIEP flap breast reconstruction procedure, skin and tissue from the abdomen is removed and implanted in the breast. For a successful repair, it is essential that the transplanted tissue develops an adequate blood supply. Failure to do so results in tissue death (necrosis) which can lead to complications such as infection, delayed wound healing and disfigurement due to scarring with attendant psychological trauma. This proposal seeks to address this by developing and constructing a prototype clinical imaging instrument based on a novel photoacoustic technology which can provide highly detailed three-dimensional maps of blood vessels. This technology offers the prospect of reducing the number of complications and the need for repeat procedures with consequent benefits in terms of reduced patient trauma and lower healthcare provider costs. Fields of science medical and health sciencesclinical medicinesurgerysurgical proceduresmedical and health sciencesclinical medicinetransplantationengineering and technologymedical engineeringdiagnostic imaging Programme(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Topic(s) ERC-2019-POC - ERC Proof of Concept Grant Call for proposal ERC-2019-PoC See other projects for this call Funding Scheme ERC-POC-LS - ERC Proof of Concept Lump Sum Pilot Coordinator UNIVERSITY COLLEGE LONDON Net EU contribution € 150 000,00 Address Gower street WC1E 6BT London United Kingdom See on map Region London Inner London — West Camden and City of London Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Beneficiaries (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all UNIVERSITY COLLEGE LONDON United Kingdom Net EU contribution € 150 000,00 Address Gower street WC1E 6BT London See on map Region London Inner London — West Camden and City of London Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00
