Deciphering the cyst nematode parasitic program by uncovering how their virulence is orchestrated

Project description

Molecular mechanisms of parasitic nematode virulence

Plant parasitic nematodes represent a significant group of plant pathogens that threaten current and future food security. One type, the cyst nematode, targets the most important crop species (tomato, potato) causing up to 80 % losses. New European regulations prohibit the future use of many effective pesticides including nematicides. The EU-funded NEMABOX project aims to study the virulence of cyst nematodes to identify new targets for sustainable biotechnological control. To be virulent, cyst nematodes must inject effector proteins into the plant. The effectors are produced in the nematode’s dorsal or sub-ventral glands and a subset of dorsal gland effectors are unified by a six base-pair non-coding DNA motif, termed the 'DOG box'. The current study will address the molecular mechanisms underlying the regulation of effectors in the gland cells.

Fields of science

• agricultural sciences › animal and dairy science › pets
• natural sciences › biological sciences › biological behavioural sciences › ethology › biological interaction
• engineering and technology › other engineering and technologies › food and beverages › food safety

Programme(s)

• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2019 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2019
See other projects for this call

Funding Scheme

MSCA-IF-EF-ST - Standard EF

Coordinator

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

Address

Trinity Lane The Old Schools
CB2 1TN Cambridge
United Kingdom

Activity type

Higher or Secondary Education Establishments

EU contribution

€ 212 933,76