Publications Peer reviewed articles (21) The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening Author(s): Andreu, I; Falcones, B; Hurst, S; Chahare, N; Quiroga, X; Le Roux, AL; Kechagia, Z; Beedle, AEM; Elosegui-Artola, A; Trepat, X; Farre, R; Betz, T; Almendros, I; Roca-Cusachs, P Published in: Nature Communications, 2021, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-021-24383-3 Digesting the mechanobiology of the intestinal epithelium Author(s): Pérez-González, Carlos; Ceada, Gerardo; Matejcic, Marija; Trepat, Xavier Published in: Current Opinion In Genetics & Development, 2022, ISSN 0959-437X Publisher: Elsevier BV DOI: 10.1016/j.gde.2021.10.005 A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration Author(s): Naoya Hino, Kimiya Matsuda, Yuya Jikko, Gembu Maryu, Katsuya Sakai, Ryu Imamura, Shinya Tsukiji, Kazuhiro Aoki, Kenta Terai, Tsuyoshi Hirashima, Xavier Trepat, Michiyuki Matsuda Published in: Developmental Cell, 2022, ISSN 1878-1551 Publisher: Elsevier DOI: 10.1016/j.devcel.2022.09.003 Optogenetic control of apical constriction induces synthetic morphogenesis in mammalian tissues Author(s): Guillermo Martínez-Ara, Núria Taberner, Mami Takayama, Elissavet Sandaltzopoulou, Casandra E. Villava, Miquel Bosch-Padrós, Nozomu Takata, Xavier Trepat, Mototsugu Eiraku, Miki Ebisuya Published in: Nature communications, 2022, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-022-33115-0 Stiffness-dependent active wetting enables optimal collective cell durotaxis Author(s): Macià Esteve Pallarès, Irina Pi-Jaumà, Isabela Corina Fortunato, Valeria Grazu, Manuel Gómez-González, Pere Roca-Cusachs, Jesus M. de la Fuente, Ricard Alert, Raimon Sunyer, Jaume Casademunt, Xavier Trepat Published in: Nature Physics, 2023, ISSN 1745-2473 Publisher: Nature Publishing Group DOI: 10.1038/s41567-022-01835-1 A mechanical G2 checkpoint controls epithelial cell division through E-cadherin-mediated regulation of Wee1-Cdk1 Author(s): Lisa Donker, Ronja Houtekamer, Marjolein Vliem, François Sipieter, Helena Canever, Manuel Gómez-González, Miquel Bosch-Padrós, Willem-Jan Pannekoek, Xavier Trepat, Nicolas Borghi, Martijn Gloerich Published in: Cell Reports, 2022, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2022.111475 Self-generated gradients steer collective migration on viscoelastic collagen networks Author(s): Andrew G. Clark, Ananyo Maitra, Cécile Jacques, Martin Bergert, Carlos Pérez-González, Anthony Simon, Luc Lederer, Alba Diz-Muñoz, Xavier Trepat, Raphaël Voituriez & Danijela Matic Vignjevic Published in: Nature Materials, 2022, ISSN 1476-1122 Publisher: Nature Publishing Group DOI: 10.1038/s41563-022-01259-5 Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system Author(s): Fidel-Nicolás Lolo, Nikhil Walani, Eric Seemann, Dobryna Zalvidea, Dácil María Pavón, Gheorghe Cojoc, Moreno Zamai, Christine Viaris de Lesegno, Fernando Martínez de Benito, Miguel Sánchez-Álvarez, Juan José Uriarte, Asier Echarri, Daniel Jiménez-Carretero, Joan-Carles Escolano, Susana A. Sánchez, Valeria R. Caiolfa, Daniel Navajas, Xavier Trepat, Jochen Guck, Christophe Lamaze, Pere Roc Published in: Nature Cell Biology, 2022, ISSN 1465-7392 Publisher: Nature Publishing Group DOI: 10.1038/s41556-022-01034-3 Epithelial cell cluster size affects force distribution in response to EGF-induced collective contractility Author(s): Chiara Zambarda, Carlos Pérez González, Andreas Schoenit, Nisha Veits, Clara Schimmer, Raimund Jung, Dirk Ollech, Joel Christian, Pere Roca-Cusachs, Xavier Trepat, Elisabetta Ada Cavalcanti-Adam Published in: European Journal of Cell Biology, 2022, ISSN 0171-9335 Publisher: Elsevier BV DOI: 10.1016/j.ejcb.2022.151274 Mechanobiological approaches to synthetic morphogenesis: learning by building Author(s): Marija Matejčić; Xavier Trepat Published in: Trends in Cell Biology, 2022, ISSN 0962-8924 Publisher: Elsevier BV DOI: 10.1016/j.tcb.2022.06.013 Involvement of Mechanical Cues in the Migration of Cajal-Retzius Cells in the Marginal Zone During Neocortical Development Author(s): Ana López-Mengual, Miriam Segura-Feliu, Raimon Sunyer, Héctor Sanz-Fraile, Jorge Otero, Francina Mesquida-Veny, Vanessa Gil, Arnau Hervera, Isidre Ferrer, Jordi Soriano, Xavier Trepat, Ramon Farré, Daniel Navajas, José Antonio del Río Published in: Frontiers in Cell and Developmental Biology, 2022, ISSN 2296-634X Publisher: Frontiers Media DOI: 10.3389/fcell.2022.886110 A mechanosensing mechanism controls plasma membrane shape homeostasis at the nanoscale Author(s): Quiroga X, Walani N, Disanza A, Chavero A, Mittens A, Tebar F, Trepat X, Parton RG, Geli MI, Scita G, Arroyo M, Le Roux AL, Roca-Cusachs P Published in: eLife, Issue 12, 2023, Page(s) e72316, ISSN 2050-084X Publisher: eLife Sciences Publications DOI: 10.7554/elife.72316 Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells Author(s): Adrià Cañellas-Socias, Carme Cortina, Xavier Hernando-Momblona, Sergio Palomo-Ponce, Eoghan J. Mulholland, Gemma Turon, Lidia Mateo, Sefora Conti, Olga Roman, Marta Sevillano, Felipe Slebe, Diana Stork, Adrià Caballé-Mestres, Antonio Berenguer-Llergo, Adrián Álvarez-Varela, Nicola Fenderico, Laura Novellasdemunt, Laura Jiménez-Gracia, Tamara Sipka, Lidia Bardia, Patricia Lorden, Julien Colo Published in: Nature, 2022, ISSN 0028-0836 Publisher: Nature Publishing Group DOI: 10.1038/s41586-022-05402-9 Mapping mechanical stress in curved epithelia of designed size and shape Author(s): Ariadna Marín-Llauradó, Sohan Kale, Adam Ouzeri, Tom Golde, Raimon Sunyer, Alejandro Torres-Sánchez, Ernest Latorre, Manuel Gómez-González, Pere Roca-Cusachs, Marino Arroyo, Xavier Trepat Published in: Nature Communications, 2023, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-023-38879-7 Mechanical control of the mammalian circadian clock via YAP/TAZ and TEAD Author(s): Juan F. Abenza, Leone Rossetti, Malèke Mouelhi, Javier Burgués, Ion Andreu, Keith Kennedy, Pere Roca-Cusachs, Santiago Marco, Jordi García-Ojalvo, Xavier Trepa Published in: Journal of Cell Biology, 2023, ISSN 0021-9525 Publisher: Rockefeller University Press DOI: 10.1083/jcb.202209120 Cancer-associated fibroblasts actively compress cancer cells and modulate mechanotransduction Author(s): Barbazan J, Pérez-González C, Gómez-González M, Dedenon M, Richon S, Latorre E, Serra M, Mariani P, Descroix S, Sens P, Trepat X, Vignjevic DM Published in: Nature Communicatios, Issue 14, 2023, Page(s) 6966, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-023-42382-4 Competition for endothelial cell polarity drives vascular morphogenesis in the mouse retina Author(s): Pedro Barbacena, Maria Dominguez-Cejudo, Catarina G. Fonseca, Manuel Gómez-González, Laura M. Faure, Georgia Zarkada, Andreia Pena, Anna Pezzarossa, Daniela Ramalho, Ylenia Giarratano, Marie Ouarné, David Barata, Isabela C. Fortunato, Lenka Henao Misikova, Ian Mauldin, Yulia Carvalho, Xavier Trepat, Pere Roca-Cusachs, Anne Eichmann, Miguel O. Bernabeu, Cláudio A. Franco Published in: Developmental Cell, 2022, ISSN 1878-1551 Publisher: Elsevier DOI: 10.1016/j.devcel.2022.09.002 The laminin–keratin link shields the nucleus from mechanical deformation and signalling Author(s): Kechagia, Z; Sáez, P; Gómez-González, M; Canales, B; Viswanadha, S; Zamarbide, M; Andreu, I; Koorman, T; Beedle, AEM; Elosegui-Artola, A; Derksen, PWB; Trepat, X; Arroyo, M; Roca-Cusachs, P Published in: Nature materials, Issue 22, 2023, Page(s) 1409-1420, ISSN 1476-1122 Publisher: Nature Publishing Group DOI: 10.1038/s41563-023-01657-3 Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration Author(s): Pérez-González C; Ceada G; Greco F; Matejcic M; Gómez-González M; Castro N; Menendez A; Kale S; Krndija D; Clark AG; Gannavarapu VR; Álvarez-Varela A; Roca-Cusachs P; Batlle E; Vignjevic DM; Arroyo M; Trepat X Published in: NATURE CELL BIOLOGY, 2021, ISSN 1465-7392 Publisher: Nature Publishing Group DOI: 10.1038/s41556-021-00699-6 Mechanical force application to the nucleus regulates nucleocytoplasmic transport Author(s): Ion Andreu, Ignasi Granero-Moya, Nimesh R. Chahare, Kessem Clein, Marc Molina-Jordán, Amy E. M. Beedle, Alberto Elosegui-Artola, Juan F. Abenza, Leone Rossetti, Xavier Trepat, Barak Raveh & Pere Roca-Cusachs Published in: Nature Cell Biology, 2022, ISSN 1465-7392 Publisher: Nature Publishing Group DOI: 10.1038/s41556-022-00927-7 Dynamic mechanochemical feedback between curved membranes and BAR protein self-organization Author(s): Le Roux, Anabel-Lise; Tozzi, Caterina; Walani, Nikhil; Quiroga, Xarxa; Zalvidea, Dobryna; Trepat, Xavier; Staykova, Margarita; Arroyo, Marino; Roca-Cusachs, Pere Published in: Nature Communications, 2021, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-021-26591-3 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
