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Determining in vivo protein structures and understanding genetic interactions using deep mutagenesis

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Neuronal perception of the social environment generates an inherited memory that controls the development and generation time of C. elegans (opens in new window)

Author(s): Marcos Francisco Perez, Mehrnaz Shamalnasab, Alejandro Mata-Cabana, María Olmedo, Mirko Francesconi, Ben Lehner
Published in: Current Biology, 2021, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2021.07.031

The impact of rare germline variants on human somatic mutation processes (opens in new window)

Author(s): Ben Lehner; Fran Supek; Mischan Vali Pour Jamnani
Published in: Crossref, Issue 1, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-31483-1

Mapping the energetic and allosteric landscapes of protein binding domains. (opens in new window)

Author(s): Andre J. Faure; Júlia Domingo; Jörn M. Schmiedel; Cristina Hidalgo-Carcedo; Guillaume Diss; Ben Lehner
Published in: Crossref, Issue 1, 2022, ISSN 1476-4687
Publisher: Nature Research
DOI: 10.1038/s41586-022-04586-4

An atlas of amyloid aggregation: the impact of substitutions, insertions, deletions and truncations on amyloid beta fibril nucleation. (opens in new window)

Author(s): Benedetta Bolognesi; Ben Lehner; Mireia Seuma
Published in: Crossref, Issue 1, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-34742-3

Higher order genetic interactions switch cancer genes from two-hit to one-hit drivers. (opens in new window)

Author(s): Park, Solip; Supek, Fran; Lehner, Ben; park
Published in: Nature Communications, Issue 1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-27242-3

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