Tracking and Targeting Tumor States at single-cell resolution in real time in vivo

Pubblicazioni

Deciphering functional tumor states at single-cell resolution.

Autori: Vegliante R, Pastushenko I, Blanpain C.
Pubblicato in: EMBO J, 2021, ISSN 0261-4189
Editore: Nature Publishing Group
DOI: 10.15252/embj.2021109221

The extracellular matrix dictates regional competence for tumour initiation

Autori: Bansaccal N, Vieugue P, Sarate R, Song Y, Minguijon E, Miroshnikova YA, Zeuschner D, Collin A, Allard J, Engelman D, Delaunois AL, Liagre M, de Groote L, Timmerman E, Van Haver D, Impens F, Salmon I, Wickström SA, Sifrim A, Blanpain C.
Pubblicato in: Nature, Numero 2023 Nov 15., 2023, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-023-06740-y

Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer

Autori: Cassier PA, Navaridas R, Bellina M, Rama N, Ducarouge B, Hernandez-Vargas H, Delord JP, Lengrand J, Paradisi A, Fattet L, Garin G, Gheit H, Dalban C, Pastushenko I, Neves D, Jelin R, Gadot N, Braissand N, Léon S, Degletagne C, Matias-Guiu X, Devouassoux-Shisheboran M, Mery-Lamarche E, Allard J, Zindy E, Decaestecker C, Salmon I, Perol D, Dolcet X, Ray-Coquard I, Blanpain C*, Bernet A*, Mehlen P*
Pubblicato in: Nature, Numero 2023 Aug 2, 2023, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-023-06367-z

NR2F2 controls malignant squamous cell carcinoma state by promoting stemness and invasion and repressing differentiation

Autori: Mauri M, Schepkens C, Lapouge G, Drogat B, Song Y, Pastushenko I, Rorive S, Blondeau J, Golstein S, Bareche Y, Miglianico M, Nkusi E, Rozzi M, Moers M, Brisebarre A, Raphael M, Dubois C, Allard J, Durdu B, Ribeiro F, Sotiriou C, Salmon I, Vakili J & Blanpain C
Pubblicato in: Nature Cancer, 2021, ISSN 2662-1347
Editore: Springer Nature Ltd
DOI: 10.1038/s43018-021-00287-5

RHOJ controls EMT-associated resistance to chemotherapy

Autori: Maud Debaugnies, Sara Rodríguez-Acebes, Jeremy Blondeau, Marie-Astrid Parent, Manuel Zocco, Yura Song, Viviane de Maertelaer, Virginie Moers, Mathilde Latil, Christine Dubois, Katia Coulonval, Francis Impens, Delphi Van Haver, Sara Dufour, Akiyoshi Uemura, Panagiota A. Sotiropoulou, Juan Méndez & Cédric Blanpain
Pubblicato in: Nature, Numero 2023 Mar 22, 2023, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-023-05838-7

Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.

Autori: Pastushenko I, Mauri F, Song Y, de Cock F, Meeusen B, Swedlund B, Impens F, Van Haver D, Opitz M, Thery M, Bareche Y, Lapouge G, Vermeersch M, Van Eycke YR, Balsat C, Decaestecker C, Sokolow Y, Hassid S, Perez-Bustillo A, Agreda-Moreno B, Rios-Buceta L, Jaen P, Redondo P, Sieira-Gil R, Millan-Cayetano JF, Sanmatrtin O, D'Haene N, Moers V, Rozzi M, Blondeau J, Lemaire S, Scozzaro S, Janssens V, De
Pubblicato in: Nature, 2021, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-020-03046-1

Cancer cell plasticity during tumor progression, metastasis and response to therapy

Autori: Pérez González, A, Bévant, Kevin, Blanpain, C
Pubblicato in: Nature Cancer, Numero 2023 Aug 3, 2023, ISSN 2662-1347
Editore: Springer Nature
DOI: 10.1038/s43018-023-00595-y

Pharmacological targeting of netrin-1 inhibits EMT in cancer

Autori: Lengrand J, Pastushenko I, Vanuytven S, Song Y, Venet D, Sarate RM, Bellina M, Moers V, Boinet A, Sifrim A, Rama N, Ducarouge B, Van Herck J, Dubois C, Scozzaro S, Lemaire S, Gieskes S, Bonni S, Collin A, Braissand N, Allard J, Zindy E, Decaestecker C, Sotiriou C, Salmon I, Mehlen P, Voet T, Bernet A, Blanpain C.
Pubblicato in: Nature, Numero 2023 Aug 2., 2023, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-023-06372-2

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