Biophysics in gene regulation - A genome wide approach

Project Information

BIGGER

Grant agreement ID: 885360

DOI

10.3030/885360

Project closed

EC signature date 29 April 2020

Start date 1 January 2021

End date 31 December 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 441 410,00

EU contribution

€ 2 411 410,00

Coordinated by

UPPSALA UNIVERSITET
Sweden

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan

Publications

Peer reviewed articles (5)

Real-time single-molecule 3D tracking in E. coli based on cross-entropy minimization

Author(s): Elias Amselem, Bo Broadwater, Tora Hävermark, Magnus Johansson & Johan Elf
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-36879-1

Pooled optical screening in bacteria using chromosomally expressed barcodes

Author(s): Ruben R. G. Soares, Daniela A. García-Soriano, Jimmy Larsson, David Fange, Dvir Schirman, Marco Grillo, Anna Knöppel, Beer Chakra Sen, Fabian Svahn, Spartak Zikrin, Michael Ratz, Mats Nilsson, Johan Elf
Published in: Communications Biology, Issue 8, 2025, ISSN 2399-3642
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s42003-025-08268-5

Regulatory elements coordinating initiation of chromosome replication to the Escherichia coli cell cycle

Author(s): Anna Knöppel, Oscar Broström, Konrad Gras, Johan Elf, David Fange
Published in: PNAS, 2023, ISSN 1091-6490
Publisher: National Academy of Science
DOI: 10.1073/pnas.2213795120

Three-dimensional localization and tracking of chromosomal loci throughout the Escherichia coli cell cycle

Author(s): Praneeth Karempudi, Konrad Gras, Elias Amselem, Spartak Zikrin, Dvir Schirman, Johan Elf
Published in: Communications Biology, Issue 7, 2024, ISSN 2399-3642
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s42003-024-07155-9

The Escherichia coli chromosome moves to the replisome

Author(s): Konrad Gras, David Fange, Johan Elf
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-50047-z

Other (3)

A dynamic 3D polymer model of the <i>Escherichia coli</i> chromosome driven by data from optical pooled screening

Author(s): Dvir Schirman, Konrad Gras, Vinodh Kandavalli, Jimmy Larsson, David Fange, Johan Elf
Published in: 2026
Publisher: openRxiv
DOI: 10.1101/2024.10.30.621082

Three-dimensional localization of fluorescent proteins in living Escherichia coli

Author(s): Praneeth Karempudi, Konrad Gras, Elias Amselem, Spartak Zikrin, Johan Elf
Published in: bioRxiv, Issue Posted October 21, 2023., 2023
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.10.20.563292

The spatial organization of replication is determined by cell size independently of chromosome copy number

Author(s): Anna Knöppel, Oscar Broström, Konrad Gras, David Fange, and Johan Elf
Published in: 2021
Publisher: BioRxiv
DOI: 10.1101/2021.10.11.463968

Thesis and dissertations (3)

Coordination of replication initiation and cell growth in Escherichia coli

Author(s): Oscar Broström
Published in: 2025, ISSN 1651-6214
Publisher: Acta Universitatis Upsaliensis,

The Dynamic Structure of the Escherichia coli Chromosome

Author(s): Konrad Gras
Published in: 2024, ISBN 978-91-513-2286-5
Publisher: Acta Universitatis Upsaliensis

Microfluidics and AI for single-cell microbiology

Author(s): Praneeth Karempudi
Published in: 2023, ISBN 978-91-513-1932-2
Publisher: Acta Universitatis Upsaliensis