High Content Microanalytical Ramanomics for Ultraquantitative Phenotyping of Individual Stem Cells and Bioengineered Organoids

Project description

An analytical platform for organoid profiling

Organoids are emerging as promising tools for drug discovery and for studying disease pathogenesis. However, challenges associated with the capacity of organoids to recapitulate the complex structure and function of actual biological tissues and organs have limited their use. To address this, scientists of the EU-funded UltraRamanomics project propose to develop a bioanalytical platform for the phenotypic profiling of organoids derived from individual stem cells and human induced pluripotent stem cells. Using spectroscopy-based biochemical measurements, the platform will offer a direct comparison of different organoid models with great spatial resolution, filling a knowledge gap in stem cell organoid research.

Fields of science

• medical and health sciences › basic medicine › pharmacology and pharmacy › drug discovery
• medical and health sciences › medical biotechnology › cells technologies › stem cells

Programme(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme
• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2019 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2019

See other projects for this call

Funding Scheme

MSCA-IF-EF-ST - Standard EF

Coordinator

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE

Net EU contribution

€ 212 933,76

Address

South Kensington Campus Exhibition Road
SW7 2AZ London
United Kingdom

Activity type

Higher or Secondary Education Establishments

Non-EU contribution

€ 0,00

Region

London › Inner London — West › Westminster