Cascade synthesis of ethanol and acetate via microbial fermentation of syngas produced photoelectrochemically by molecular catalysts on BiVO4-perovskite tandem artificial leaf

Projektinformationen

MicrobialLEAF

ID Finanzhilfevereinbarung: 891338

DOI

10.3030/891338

Projekt abgeschlossen

EK-Unterschriftsdatum 15 April 2020

Startdatum 1 Juni 2021

Enddatum 31 Mai 2023

Finanziert unter

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Gesamtkosten

€ 224 933,76

EU-Beitrag

€ 224 933,76

Koordiniert durch

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom

Periodic Reporting for period 1 - MicrobialLEAF (Cascade synthesis of ethanol and acetate via microbial fermentation of syngas produced photoelectrochemically by molecular catalysts on BiVO4-perovskite tandem artificial leaf)

Berichtszeitraum: 2021-06-01 bis 2023-05-31

Zusammenfassung vom Kontext und den Gesamtzielen des Projekts

Our current dependence on fossil fuels for producing fuels and chemicals has significant environmental repercussions. The escalating greenhouse gas emissions, particularly carbon dioxide (CO2), are accelerating climate change and global warming. Consequently, there's a pressing need for sustainable methods to manufacture important commodities while also addressing rising atmospheric CO2 levels.

Tapping into nature's unparalleled catalytic ability, the EU-backed MicrobialLEAF project employs bacteria to convert CO2 into multi-carbon, energy-dense chemicals and fuels, and demonstrates this in a novel bacterial-synthetic biohybrid system. This approach holds great societal importance as it presents an innovative method to transform CO2 directly into valuable chemicals by synergistically combining biological and inorganic components. This approach offers a promising pathway for a greener and more sustainable future.

Arbeit, die ab Beginn des Projekts bis zum Ende des durch den Bericht erfassten Berichtszeitraums geleistet wurde, und die wichtigsten bis dahin erzielten Ergebnisse

The project unfolded in three phases:

First phase:
- Developed synthetic materials capable of converting carbon dioxide (CO2) and water into syngas (a mixture of carbon monoxide and hydrogen) for bacterial consumption.
- Adapted bacteria that could thrive exclusively on syngas to produce multi-carbon compounds acetate and ethanol.

Second phase:
- Designed an innovative device that synergistically combined the synthetic materials and bacteria for optimised performance.

Third phase:
- Implemented the envisioned proof-of-concept device. In this setup, the synthetic materials converted CO2 and water into syngas, which the adapted bacteria then fermented into acetate and ethanol.

Project deliverables:
1. A curated library of synthetic materials capable of transforming CO2 and water into syngas.
2. A method for the adaptation of the chosen bacteria to syngas fermentation.
3. Design of a proof-of-concept device that enabled the integration of synthetic materials and bacteria.
4. Demonstrated successful conversion of syngas to acetate and ethanol using the integrated bacteria-inorganic material device.

Dissemination:
1. A part of the findings has been shared through publications and conference presentations.
2. Two additional manuscripts focusing on deliverables 2 and 3/4 are under preparation.
3. The researcher has actively engaged in outreach events and co-organised a conference in the theme of biological-inorganic biohybrid systems.

Fortschritte, die über den aktuellen Stand der Technik hinausgehen und voraussichtliche potenzielle Auswirkungen (einschließlich der bis dato erzielten sozioökonomischen Auswirkungen und weiter gefassten gesellschaftlichen Auswirkungen des Projekts)

Advancements beyond state of the art:
- Pioneered a novel device design that integrates synthetic materials with bacteria, aiming for the sustainable production of chemicals and fuels.
- Demonstrated that the proof-of concept could operate stably for 170 hours, converting CO2 and water into multicarbon acetate and ethanol.

The findings from this MSCA fellowship hold the potential to significantly shape research directions in biotechnology. The innovative device introduces an integrated cascade approach for the synthesis of chemicals and fuels. This design can be expanded to incorporate other synthetic materials and microbial systems, paving the way for the production of multicarbon products beyond just acetate and ethanol.

Work performed throughout the project