Studying cortical neurons during innate vocalisation
Almost all mammals vocalise to communicate. Recent studies on non-human primates indicate that certain neurons in the ventrolateral prefrontal cortex and anterior cingulate cortex are highly active before and during innate vocal production. However, most of the genetic tools needed to map, monitor and manipulate the cortical neurons active during innate vocal behaviours are inapplicable to monkeys and rats. The functional and anatomical relationship between these neuronal circuits relevant to innate vocal patterning therefore remains unknown. The EU-funded CCINB project aims to identify PLC and C2 neurons active during ultrasonic vocalisation and explore their interaction with subcortical vocal circuits. To that end, it will exploit the wide range of genetic and physiological tools available in the mouse. The project will provide insight into innate mammalian vocalisation.
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