Instructing Immune System to Regenerate Musculoskeletal Tissues via Structurally Programmable Bio-Inks

Información del proyecto

ImmunoBioInks

Identificador del acuerdo de subvención: 893099

DOI

10.3030/893099

Proyecto cerrado

Fecha de la firma de la CE 16 Abril 2020

Fecha de inicio 1 Julio 2021

Fecha de finalización 30 Junio 2023

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 191 149,44

Aportación de la UE

€ 191 149,44

Coordinado por

AO FORSCHUNGSINSTITUT DAVOS
Switzerland

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (16)

EXPECT: A thermosensitive embedded bioprinting platform for guided spatial cell organization

Autores: Athanasia Pylostomou, Jacek K. Wychowaniec, Riccardo Tognato, Sarah T. Egger, Gion U. Alig, Charlotte J.C. Edwards-Gayle, Fatemeh Safari, Jennifer R. Weiser, Dagnija Loca, Matteo D'Este, Tiziano Serra, Andrea J. Vernengo
Publicado en: Smart Materials in Medicine, Edición 6, 2026, Página(s) 347-367, ISSN 2590-1834
Editor: Elsevier BV
DOI: 10.1016/j.smaim.2025.09.002

A continuum mechanical porous media model for vertebroplasty: Numerical simulations and experimental validation

Autores: Zubin Trivedi, Dominic Gehweiler, Jacek K. Wychowaniec, Tim Ricken, Boyko Gueorguiev, Arndt Wagner & Oliver Röhrle
Publicado en: Biomechanics and Modeling in Mechanobiology, 2023, ISSN 1617-7959
Editor: Springer Verlag
DOI: 10.1007/s10237-023-01715-4

Rheological Analysis and Evaluation of Measurement Techniques for Curing Poly(Methyl Methacrylate) Bone Cement in Vertebroplasty

Autores: Zubin Trivedi, Jacek K. Wychowaniec, Dominic Gehweiler, Christoph M. Sprecher, Andreas Boger, Boyko Gueorguiev, Matteo D’Este, Tim Ricken, Oliver Röhrle
Publicado en: ACS Biomaterials Science & Engineering, Edición 10, 2025, Página(s) 4575-4586, ISSN 2373-9878
Editor: American Chemical Society (ACS)
DOI: 10.1021/acsbiomaterials.4c00417

Effect of Tyrosine-Containing Self-Assembling β-Sheet Peptides on Macrophage Polarization and Inflammatory Response

Autores: Jacek K. Wychowaniec, Ezgi Irem Bektas, Marcia Muerner, Jiranuwat Sapudom, Martin Šrejber, Marielle Airoldi, Roland Schmidt, Andrea J. Vernengo, Charlotte J. C. Edwards-Gayle, Paul Sean Tipay, Michal Otyepka, Jeremy Teo, David Eglin, Matteo D’Este
Publicado en: ACS Applied Materials & Interfaces, Edición 17, 2025, Página(s) 27740-27758, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.1021/acsami.4c19900

Emerging Magnetic Fabrication Technologies Provide Controllable Hierarchically-Structured Biomaterials and Stimulus Response for Biomedical Applications

Autores: Jacek K. Wychowaniec; Dermot F. Brougham
Publicado en: Advanced Science, Edición 21983844, 2022, ISSN 2198-3844
Editor: Wiley
DOI: 10.1002/advs.202202278

Effect of Steam Sterilisation on Physico-Chemical Properties of Antibacterial Covalently Cross-Linked Ε-Polylysine/Hyaluronic Acid Hydrogels

Autores: Artemijs Sceglovs Jacek K. Wychowaniec Ingus Skadiņš Aigars Reinis Matteo D'Este Kristine Salma-Ancane
Publicado en: Carbohydrate Polymer Technologies and Applications, 2023, ISSN 2666-8939
Editor: Elsevier
DOI: 10.2139/ssrn.4523054

Functional hydrogels as therapeutic tools for spinal cord injury: New perspectives on immunopharmacological interventions

Autores: Ciara M. Walsh, Jacek K. Wychowaniec, Dermot F. Brougham, Dearbhaile Dooley Ciara M. Walsh and Jacek K. Wychowaniec contributed equally to this work.
Publicado en: Pharmacology & Therapeutics, 2021, Página(s) 108043, ISSN 0163-7258
Editor: Pergamon Press
DOI: 10.1016/j.pharmthera.2021.108043

Preparation and Characterization of Photo-Cross-Linkable Methacrylated Silk Fibroin and Methacrylated Hyaluronic Acid Composite Hydrogels

Autores: Jhaleh Amirian, Jacek K. Wychowaniec, Matteo D′Este, Andrea J. Vernengo, Anastasija Metlova, Antons Sizovs, Agnese Brangule, Dace Bandere
Publicado en: Biomacromolecules, Edición 25, 2025, Página(s) 7078-7097, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.4c00319

An In Vitro and Ex Vivo Analysis of the Potential of GelMA Hydrogels as a Therapeutic Platform for Preclinical Spinal Cord Injury

Autores: Ciara M. Walsh, Jacek K. Wychowaniec, Louise Costello, Dermot F. Brougham, Dearbhaile Dooley
Publicado en: Advanced Healthcare Materials, 2023, ISSN 2192-2659
Editor: World Scientific
DOI: 10.1002/adhm.202300951

Thermoresponsive polymers for cell support: poloxamers as a case study of promise and challenge

Autores: Shane Clerkin, Krutika Singh, Danielle Winning, Ivan Krupa, John Crean, Dermot F. Brougham, Jacek K. Wychowaniec
Publicado en: Journal of Materials Chemistry B, Edición 13, 2025, Página(s) 9351-9376, ISSN 2050-7518
Editor: Royal Society of Chemistry
DOI: 10.1039/d5tb00588d

Bone microphysiological models for biomedical research

Autores: Francisco Verdugo-Avello, Jacek K. Wychowaniec, Carlos A. Villacis-Aguirre, Matteo D'Este, Jorge R. Toledo
Publicado en: Lab on a Chip, Edición 25, 2025, Página(s) 806-836, ISSN 1473-0197
Editor: Royal Society of Chemistry
DOI: 10.1039/d4lc00762j

Effect of crosslinking strategy on the biological, antibacterial and physicochemical performance of hyaluronic acid and ɛ-polylysine based hydrogels

Autores: K. Salma Ancane, A. Sceglovs, E. Tracuma, J. Wychowaniec, Kristine Aunina, A. Ramata-Stunda, V. Nikolajeva, D. Loca
Publicado en: International Journal of Biological Macromolecules, Edición Volume 208, 31 May 2022, 2022, Página(s) 995-1008, ISSN 0141-8130
Editor: Elsevier BV
DOI: 10.1016/j.ijbiomac.2022.03.207

Alginate microbeads and hydrogels delivering meropenem and bacteriophages to treat Pseudomonas aeruginosa fracture-related infections

Autores: Baixing Chen, Luis Ponce Benavente, Marco Chittò, Jacek K. Wychowaniec, Virginia Post, Matteo D'Este, Caroline Constant, Stephan Zeiter, Wenli Feng, Mercedes González Moreno, Andrej Trampuz, Jeroen Wagemans, Jolien Onsea , R. Geoff Richards, Rob Lavigne, T. Fintan Moriarty, Willem-Jan Metsemakers
Publicado en: Journal of Controlled Release, Edición Volume 364, December 2023, Pages 159-173, 2023, ISSN 1873-4995
Editor: Elsevier
DOI: 10.1016/j.jconrel.2023.10.029

Charge Directed Selective Co‐Assembly of Ionic Complementary Peptide Binary Mixtures

Autores: Abdulwahhab Khedr, Mohamed A. N. Soliman, Alfred Corrigan, Tarsem Sahota, Rachel Armitage, Natalie Allcock, Jeyapriya T. Jegadeesan, Mahetab H. Amer, Reem Alazragi, Zeeshan Ahmad, Jacek K. Wychowaniec, Mohamed A. Elsawy
Publicado en: Small, Edición 22, 2026, Página(s) e13140, ISSN 1613-6810
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202513140

Hierarchical porous metal–organic gels and derived materials: from fundamentals to potential applications

Autores: Jacek K. Wychowaniec, Haneesh Saini, Błażej Scheibe, Deepak P. Dubal, Andreas Schneemann and Kolleboyina Jayaramulu
Publicado en: Chemical Society Reviews, 2022, Página(s) 9068-9126, ISSN 0306-0012
Editor: Royal Society of Chemistry
DOI: 10.1039/d2cs00585a

Versatile Potential of Photo-Cross-Linkable Silk Fibroin: Roadmap from Chemical Processing Toward Regenerative Medicine and Biofabrication Applications

Autores: Amirina, Jhaleh; Wychowaniec, Jacek, K.; Zendehdel, Ehsan Amel; Sharma, Gaurav; Brangule, Agnese; Bandere, Dace
Publicado en: Biomacromolecules, Edición 1, 2023, ISSN 1526-4602
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.3c00098

Other (2)

Self-assembly of Tyrosine-containing Peptides into Injectable Hydrogels with Distinct Nanostructures is Key in Determining Inflammatory Response of Macrophages

Autores: Jacek K. Wychowaniec, Ezgi Irem Bektas, Marcia Mürner, Jiranuwat Sapudom, Martin Šrejber, Marielle Airoldi, Roland Schmidt, Andrea J. Vernengo, Charlotte J.C. Edwards-Gayle, Paul Sean Tipay, Michal Otyepka, Jeremy Teo, David Eglin, Matteo D'Este
Publicado en: 2026
Editor: American Chemical Society (ACS)
DOI: 10.26434/chemrxiv-2024-bn5sm-v2

Harnessing Thermogel Actuation for Driving Directional Stromal Cell Communication and Migration into Columnar Arrays

Autores: Andrea Vernengo, Athanasia Pylostomou, Jacek Wychowaniec, Riccardo Tognato, Sarah Egger, Gion Ursin, Charlotte Edwards-Gayle, Jennifer Weiser, Dagnija Loca, Matteo Deste, Tiziano Serra
Publicado en: 2025
Editor: Springer Science and Business Media LLC
DOI: 10.21203/rs.3.rs-3827648/v1

Book chapters (1)

Characterization of peptide-based nanomaterials

Autores: C. J. C. Edwards-Gayle and J. Wychowaniec
Publicado en: Peptide Bionanomaterials: From Design to Application, 2023, ISBN 978-3-031-29360-3
Editor: Springer
DOI: 10.1007/978-3-031-29360-3_8

Conference proceedings (1)

Analysing the bone cement flow in the injection apparatus during vertebroplasty

Autores: Zubin Trivedi, Dominic Gehweiler, Jacek K. Wychowaniec, Tim Ricken, Boyko Gueorguiev-Rüegg, Arndt Wagner, Oliver Röhrle
Publicado en: Proceedings in Applied Mathematics and Mechanics, 2023, ISSN 1617-7061
Editor: Proceedings in Applied Mathematics and Mechanics
DOI: 10.1002/pamm.202200295