Instructing Immune System to Regenerate Musculoskeletal Tissues via Structurally Programmable Bio-Inks

Informazioni relative al progetto

ImmunoBioInks

ID dell’accordo di sovvenzione: 893099

DOI

10.3030/893099

Progetto chiuso

Data della firma CE 16 Aprile 2020

Data di avvio 1 Luglio 2021

Data di completamento 30 Giugno 2023

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 191 149,44

Contributo UE

€ 191 149,44

Coordinato da

AO FORSCHUNGSINSTITUT DAVOS
Switzerland

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (16)

EXPECT: A thermosensitive embedded bioprinting platform for guided spatial cell organization

Autori: Athanasia Pylostomou, Jacek K. Wychowaniec, Riccardo Tognato, Sarah T. Egger, Gion U. Alig, Charlotte J.C. Edwards-Gayle, Fatemeh Safari, Jennifer R. Weiser, Dagnija Loca, Matteo D'Este, Tiziano Serra, Andrea J. Vernengo
Pubblicato in: Smart Materials in Medicine, Numero 6, 2026, Pagina/e 347-367, ISSN 2590-1834
Editore: Elsevier BV
DOI: 10.1016/j.smaim.2025.09.002

A continuum mechanical porous media model for vertebroplasty: Numerical simulations and experimental validation

Autori: Zubin Trivedi, Dominic Gehweiler, Jacek K. Wychowaniec, Tim Ricken, Boyko Gueorguiev, Arndt Wagner & Oliver Röhrle
Pubblicato in: Biomechanics and Modeling in Mechanobiology, 2023, ISSN 1617-7959
Editore: Springer Verlag
DOI: 10.1007/s10237-023-01715-4

Rheological Analysis and Evaluation of Measurement Techniques for Curing Poly(Methyl Methacrylate) Bone Cement in Vertebroplasty

Autori: Zubin Trivedi, Jacek K. Wychowaniec, Dominic Gehweiler, Christoph M. Sprecher, Andreas Boger, Boyko Gueorguiev, Matteo D’Este, Tim Ricken, Oliver Röhrle
Pubblicato in: ACS Biomaterials Science & Engineering, Numero 10, 2025, Pagina/e 4575-4586, ISSN 2373-9878
Editore: American Chemical Society (ACS)
DOI: 10.1021/acsbiomaterials.4c00417

Effect of Tyrosine-Containing Self-Assembling β-Sheet Peptides on Macrophage Polarization and Inflammatory Response

Autori: Jacek K. Wychowaniec, Ezgi Irem Bektas, Marcia Muerner, Jiranuwat Sapudom, Martin Šrejber, Marielle Airoldi, Roland Schmidt, Andrea J. Vernengo, Charlotte J. C. Edwards-Gayle, Paul Sean Tipay, Michal Otyepka, Jeremy Teo, David Eglin, Matteo D’Este
Pubblicato in: ACS Applied Materials & Interfaces, Numero 17, 2025, Pagina/e 27740-27758, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/acsami.4c19900

Emerging Magnetic Fabrication Technologies Provide Controllable Hierarchically-Structured Biomaterials and Stimulus Response for Biomedical Applications

Autori: Jacek K. Wychowaniec; Dermot F. Brougham
Pubblicato in: Advanced Science, Numero 21983844, 2022, ISSN 2198-3844
Editore: Wiley
DOI: 10.1002/advs.202202278

Effect of Steam Sterilisation on Physico-Chemical Properties of Antibacterial Covalently Cross-Linked Ε-Polylysine/Hyaluronic Acid Hydrogels

Autori: Artemijs Sceglovs Jacek K. Wychowaniec Ingus Skadiņš Aigars Reinis Matteo D'Este Kristine Salma-Ancane
Pubblicato in: Carbohydrate Polymer Technologies and Applications, 2023, ISSN 2666-8939
Editore: Elsevier
DOI: 10.2139/ssrn.4523054

Functional hydrogels as therapeutic tools for spinal cord injury: New perspectives on immunopharmacological interventions

Autori: Ciara M. Walsh, Jacek K. Wychowaniec, Dermot F. Brougham, Dearbhaile Dooley Ciara M. Walsh and Jacek K. Wychowaniec contributed equally to this work.
Pubblicato in: Pharmacology & Therapeutics, 2021, Pagina/e 108043, ISSN 0163-7258
Editore: Pergamon Press
DOI: 10.1016/j.pharmthera.2021.108043

Preparation and Characterization of Photo-Cross-Linkable Methacrylated Silk Fibroin and Methacrylated Hyaluronic Acid Composite Hydrogels

Autori: Jhaleh Amirian, Jacek K. Wychowaniec, Matteo D′Este, Andrea J. Vernengo, Anastasija Metlova, Antons Sizovs, Agnese Brangule, Dace Bandere
Pubblicato in: Biomacromolecules, Numero 25, 2025, Pagina/e 7078-7097, ISSN 1525-7797
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.4c00319

An In Vitro and Ex Vivo Analysis of the Potential of GelMA Hydrogels as a Therapeutic Platform for Preclinical Spinal Cord Injury

Autori: Ciara M. Walsh, Jacek K. Wychowaniec, Louise Costello, Dermot F. Brougham, Dearbhaile Dooley
Pubblicato in: Advanced Healthcare Materials, 2023, ISSN 2192-2659
Editore: World Scientific
DOI: 10.1002/adhm.202300951

Thermoresponsive polymers for cell support: poloxamers as a case study of promise and challenge

Autori: Shane Clerkin, Krutika Singh, Danielle Winning, Ivan Krupa, John Crean, Dermot F. Brougham, Jacek K. Wychowaniec
Pubblicato in: Journal of Materials Chemistry B, Numero 13, 2025, Pagina/e 9351-9376, ISSN 2050-7518
Editore: Royal Society of Chemistry
DOI: 10.1039/d5tb00588d

Bone microphysiological models for biomedical research

Autori: Francisco Verdugo-Avello, Jacek K. Wychowaniec, Carlos A. Villacis-Aguirre, Matteo D'Este, Jorge R. Toledo
Pubblicato in: Lab on a Chip, Numero 25, 2025, Pagina/e 806-836, ISSN 1473-0197
Editore: Royal Society of Chemistry
DOI: 10.1039/d4lc00762j

Effect of crosslinking strategy on the biological, antibacterial and physicochemical performance of hyaluronic acid and ɛ-polylysine based hydrogels

Autori: K. Salma Ancane, A. Sceglovs, E. Tracuma, J. Wychowaniec, Kristine Aunina, A. Ramata-Stunda, V. Nikolajeva, D. Loca
Pubblicato in: International Journal of Biological Macromolecules, Numero Volume 208, 31 May 2022, 2022, Pagina/e 995-1008, ISSN 0141-8130
Editore: Elsevier BV
DOI: 10.1016/j.ijbiomac.2022.03.207

Alginate microbeads and hydrogels delivering meropenem and bacteriophages to treat Pseudomonas aeruginosa fracture-related infections

Autori: Baixing Chen, Luis Ponce Benavente, Marco Chittò, Jacek K. Wychowaniec, Virginia Post, Matteo D'Este, Caroline Constant, Stephan Zeiter, Wenli Feng, Mercedes González Moreno, Andrej Trampuz, Jeroen Wagemans, Jolien Onsea , R. Geoff Richards, Rob Lavigne, T. Fintan Moriarty, Willem-Jan Metsemakers
Pubblicato in: Journal of Controlled Release, Numero Volume 364, December 2023, Pages 159-173, 2023, ISSN 1873-4995
Editore: Elsevier
DOI: 10.1016/j.jconrel.2023.10.029

Charge Directed Selective Co‐Assembly of Ionic Complementary Peptide Binary Mixtures

Autori: Abdulwahhab Khedr, Mohamed A. N. Soliman, Alfred Corrigan, Tarsem Sahota, Rachel Armitage, Natalie Allcock, Jeyapriya T. Jegadeesan, Mahetab H. Amer, Reem Alazragi, Zeeshan Ahmad, Jacek K. Wychowaniec, Mohamed A. Elsawy
Pubblicato in: Small, Numero 22, 2026, Pagina/e e13140, ISSN 1613-6810
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202513140

Hierarchical porous metal–organic gels and derived materials: from fundamentals to potential applications

Autori: Jacek K. Wychowaniec, Haneesh Saini, Błażej Scheibe, Deepak P. Dubal, Andreas Schneemann and Kolleboyina Jayaramulu
Pubblicato in: Chemical Society Reviews, 2022, Pagina/e 9068-9126, ISSN 0306-0012
Editore: Royal Society of Chemistry
DOI: 10.1039/d2cs00585a

Versatile Potential of Photo-Cross-Linkable Silk Fibroin: Roadmap from Chemical Processing Toward Regenerative Medicine and Biofabrication Applications

Autori: Amirina, Jhaleh; Wychowaniec, Jacek, K.; Zendehdel, Ehsan Amel; Sharma, Gaurav; Brangule, Agnese; Bandere, Dace
Pubblicato in: Biomacromolecules, Numero 1, 2023, ISSN 1526-4602
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.3c00098

Other (2)

Self-assembly of Tyrosine-containing Peptides into Injectable Hydrogels with Distinct Nanostructures is Key in Determining Inflammatory Response of Macrophages

Autori: Jacek K. Wychowaniec, Ezgi Irem Bektas, Marcia Mürner, Jiranuwat Sapudom, Martin Šrejber, Marielle Airoldi, Roland Schmidt, Andrea J. Vernengo, Charlotte J.C. Edwards-Gayle, Paul Sean Tipay, Michal Otyepka, Jeremy Teo, David Eglin, Matteo D'Este
Pubblicato in: 2026
Editore: American Chemical Society (ACS)
DOI: 10.26434/chemrxiv-2024-bn5sm-v2

Harnessing Thermogel Actuation for Driving Directional Stromal Cell Communication and Migration into Columnar Arrays

Autori: Andrea Vernengo, Athanasia Pylostomou, Jacek Wychowaniec, Riccardo Tognato, Sarah Egger, Gion Ursin, Charlotte Edwards-Gayle, Jennifer Weiser, Dagnija Loca, Matteo Deste, Tiziano Serra
Pubblicato in: 2025
Editore: Springer Science and Business Media LLC
DOI: 10.21203/rs.3.rs-3827648/v1

Book chapters (1)

Characterization of peptide-based nanomaterials

Autori: C. J. C. Edwards-Gayle and J. Wychowaniec
Pubblicato in: Peptide Bionanomaterials: From Design to Application, 2023, ISBN 978-3-031-29360-3
Editore: Springer
DOI: 10.1007/978-3-031-29360-3_8

Conference proceedings (1)

Analysing the bone cement flow in the injection apparatus during vertebroplasty

Autori: Zubin Trivedi, Dominic Gehweiler, Jacek K. Wychowaniec, Tim Ricken, Boyko Gueorguiev-Rüegg, Arndt Wagner, Oliver Röhrle
Pubblicato in: Proceedings in Applied Mathematics and Mechanics, 2023, ISSN 1617-7061
Editore: Proceedings in Applied Mathematics and Mechanics
DOI: 10.1002/pamm.202200295