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Cryo analytical microscopy of cell-mediated mineralization in models of bone disease

Project description

Imaging of bone mineralisation

Bone mineralisation, the deposition of calcium phosphate on the bone matrix, is central for maintaining bone mechanical integrity and remodelling. However, the mechanism by which osteoblasts regulate this process remains poorly understood. The EU-funded BoneImaging project aims to elucidate the process of bone mineralisation during development in unique animal models of bone pathologies. By using state-of-the-art imaging techniques, scientists will investigate alterations in these processes between healthy and pathologic tissues such as in leukaemia or as a consequence of treatment. Results will guide tissue engineering approaches for restoring bone and help identify targeted treatments.


Net EU contribution
€ 212 933,76
WC2R 2LS London
United Kingdom

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London Inner London — West Westminster
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00