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Microbiota modulation through horizontal gene transfer.

Project description

Microbiota and horizontal gene transfer

Microbes are connected with the immune system, and altering gut microbiota (GM) composition and function might improve health. Changing species representation through dietary or lifestyle modifications may be difficult because of the small effects of the factors influencing GM composition. The host selection and competition of resident microbes limit the strain engraftment necessary for the effect of fecal transfers and probiotic cocktails. The goal of the EU-funded MiMoZa project is to determine the horizontal gene transfer (HGT) rates of specific functions within the gut microbiome. Researchers aim to determine the HGT rates within the animal gut under natural and HGT-enhancing conditions. They plan to develop methods to examine HGT in metagenomic datasets and determine the relative importance of the factors influencing HGT.

Coordinator

VIB VZW
Net EU contribution
€ 266 425,92
Address
Rijvisschestraat 120
9052 Zwijnaarde - Gent
Belgium

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Region
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent
Activity type
Research Organisations
Other funding
€ 0,00

Partners (1)

Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

CORNELL UNIVERSITY
United States
Net EU contribution
€ 0,00
Address
Pine Tree Road 373
14850 Ithaca Ny

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Activity type
Higher or Secondary Education Establishments
Other funding
€ 177 265,92