Project description
Untangling the functional and neuronal interconnections between right and left hemispheres
The corpus callosum is a c-shaped structure under the cortex consisting of about 200 million axons that interconnect the left and right hemispheres. It integrates sensory, motor and cognitive signals from the two sides, and disruption of this connection has been linked to numerous diseases and disorders. However, the neural substrates of the clinical manifestations are largely unknown. The ambitious EU-funded CCMuPWA project is developing highly sensitive techniques to find answers. Scientists are stimulating the corpus callosum in behaving rats while utilising enhanced multimodal functional magnetic resonance imaging (fMRI) and calcium recording to characterise brain activity, including the calcium dynamics of astrocytes. Outcomes should yield a holistic picture of neuroglial interactions in the corpus callosum of normal and diseased brains.
Fields of science
- engineering and technologymaterials engineeringfibers
- medical and health sciencesbasic medicineneurologyepilepsy
- natural scienceschemical sciencesinorganic chemistryalkaline earth metals
- medical and health sciencesclinical medicinepsychiatryschizophrenia
- engineering and technologyelectrical engineering, electronic engineering, information engineeringinformation engineeringtelecommunicationsradio technology
Programme(s)
Funding Scheme
MSCA-IF-GF - Global Fellowships
Coordinator
80539 Munchen
Germany
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Partners (1)
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
48824 East Lansing, Michigan
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