New fertility protocol for polycystic ovary syndrome
Nearly one in five women suffers from polycystic ovary syndrome (PCOS) and presents with polycystic ovarian morphology, ovulatory dysfunction and infertility. Oocyte maturation and competence largely depend on the surrounding cumulus cells which provide paracrine signals through cell-to-cell communication. To determine the potential causative factor of infertility in PCOS, scientists of the EU-funded POMOLIM project are investigating the gene expression profile and epigenetic changes encountered in cumulus cells in these women. The project's results are expected to improve fertility treatment protocols for women with PCOS and advance in vitro maturation (IVM) of PCOS oocytes as an alternative approach.
Fields of science
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