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Circular DNA in diagnosis and disease models


Discovery and Proof-of-Concept Study of Nuclease Activity as a Novel Biomarker for Breast Cancer Tumors

Author(s): Luiza I. Hernandez, Marcos J. Araúzo-Bravo, Daniela Gerovska, Ricardo Rezola Solaun, Isabel Machado, Alien Balian, Juliana Botero, Tania Jiménez, Olaia Zuriarrain Bergara, Lide Larburu Gurruchaga, Ander Urruticoechea, Frank J. Hernandez
Published in: Cancers, Issue 13/2, 2021, Page(s) 276, ISSN 2072-6694
DOI: 10.3390/cancers13020276

Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning

Author(s): Xi Xiang, Giulia I. Corsi, Christian Anthon, Kunli Qu, Xiaoguang Pan, Xue Liang, Peng Han, Zhanying Dong, Lijun Liu, Jiayan Zhong, Tao Ma, Jinbao Wang, Xiuqing Zhang, Hui Jiang, Fengping Xu, Xin Liu, Xun Xu, Jian Wang, Huanming Yang, Lars Bolund, George M. Church, Lin Lin, Jan Gorodkin, Yonglun Luo
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
DOI: 10.1038/s41467-021-23576-0

FOntCell: Fusion of Ontologies of Cells

Author(s): Javier Cabau-Laporta, Alex M. Ascensión, Mikel Arrospide-Elgarresta, Daniela Gerovska, Marcos J. Araúzo-Bravo
Published in: Frontiers in Cell and Developmental Biology, Issue 9, 2021, ISSN 2296-634X
DOI: 10.3389/fcell.2021.562908

Genome Scale Modeling to Study the Metabolic Competition between Cells in the Tumor Microenvironment

Author(s): Itziar Frades, Carles Foguet, Marta Cascante, Marcos J. Araúzo-Bravo
Published in: Cancers, 2021, ISSN 2072-6694
DOI: 10.3390/cancers13184609

An Integrative Omics Approach Reveals Involvement of BRCA1 in Hepatic Metastatic Progression of Colorectal Cancer

Author(s): Daniela Gerovska, Gorka Larrinaga, Jon Danel Solano-Iturri, Joana Márquez, Patricia García Gallastegi, Abdel-Majid Khatib, Gereon Poschmann, Kai Stühler, María Armesto, Charles H. Lawrie, Iker Badiola, Marcos J. Araúzo-Bravo
Published in: Cancers, Issue 12/9, 2020, Page(s) 2380, ISSN 2072-6694
DOI: 10.3390/cancers12092380

GeromiRs Are Downregulated in the Tumor Microenvironment during Colon Cancer Colonization of the Liver in a Murine Metastasis Model

Author(s): Daniela Gerovska, Patricia Garcia-Gallastegi, Olatz Crende, Joana Márquez, Gorka Larrinaga, Maite Unzurrunzaga, Marcos J. Araúzo-Bravo, Iker Badiola
Published in: International Journal of Molecular Sciences, Issue 22/9, 2021, Page(s) 4819, ISSN 1422-0067
DOI: 10.3390/ijms22094819

Proprotein convertases blockage up-regulates specifically metallothioneins coding genes in human colon cancer stem cells

Author(s): Daniela Gerovska, Patricia García-Gallastegi, Jean Descarpentrie, Olatz Crende, María Casado-Andrés, Ander Martín, Jokin Eguia, Abdel-Majid Khatib, Marcos J. Araúzo-Bravo, Iker Badiola
Published in: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Issue 1868/3, 2021, Page(s) 118912, ISSN 0167-4889
DOI: 10.1016/j.bbamcr.2020.118912