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Computational discovery and design of disease-beating nutrition

Project description

Tailored diets using a computational approach

Nutrition plays a fundamental role in disease prevention and outcome during and after therapy since food contains ingredients that can function more or less as drugs. However, the large number of potential ingredient combinations makes it virtually impossible to optimise food profiles through standard experimental approaches. To this end, the EU-funded Hyperfoods project proposes to adopt a machine learning approach for the computational discovery and design of personalised nutrition. The Hyperfoods technology could pave the way for tailored diets to promote population well-being, help tackle diseases such as cancer and sustain the healthcare system.

Objective

With rapidly ageing populations, the world is experiencing an unsustainable healthcare and economic burden from chronic diseases such as cancer, cardiovascular, metabolic and neurodegenerative disorders. Diet and nutritional factors play an essential role in the prevention of these diseases and significantly influence disease outcome in patients during and after therapy. Everyday food ingredients contain multiple drug-like molecules that can potentially prevent or beat diseases. For example, it is estimated that up to half of oncological diseases can be prevented by dietary choices. The wide adoption of tailored health-promoting diets potentially has a revolutionary impact on the population wellbeing and long-term sustainability of the healthcare systems. However, due to an exponentially large number of combinations of the ingredients, their sourcing, processing, preparation, and preservation methods, it is virtually impossible to use traditional experimental approaches to optimise the health-promoting molecular profiles of foods. Hyperfoods will use novel graph-based ML methods to provide the technological capabilities for the computational discovery and design of personalised nutrition. We will explore the commercial opportunities of our technology for currently unmet business needs in global health, in particular cancer treatments.

Host institution

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Net EU contribution
€ 150 000,00
Address
SOUTH KENSINGTON CAMPUS EXHIBITION ROAD
SW7 2AZ LONDON
United Kingdom

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Region
London Inner London — West Westminster
Activity type
Higher or Secondary Education Establishments
Links
Total cost
No data

Beneficiaries (1)