Descrizione del progetto
Diete personalizzate grazie ad un approccio computazionale
La nutrizione svolge un ruolo fondamentale nella prevenzione delle malattie e negli esiti durante e dopo la terapia, poiché il cibo contiene ingredienti che possono funzionare più o meno come farmaci. Tuttavia, il gran numero di potenziali combinazioni di ingredienti rende praticamente impossibile ottimizzare i profili alimentari attraverso approcci sperimentali standard. A tal fine, il progetto Hyperfoods, finanziato dall’UE, si propone di adottare un approccio di apprendimento automatico per la scoperta computazionale e la progettazione di un’alimentazione personalizzata. La tecnologia Hyperfoods potrebbe aprire la strada a diete personalizzate per promuovere il benessere della popolazione, aiutare ad affrontare malattie come il cancro e sostenere il sistema sanitario.
Obiettivo
With rapidly ageing populations, the world is experiencing an unsustainable healthcare and economic burden from chronic diseases such as cancer, cardiovascular, metabolic and neurodegenerative disorders. Diet and nutritional factors play an essential role in the prevention of these diseases and significantly influence disease outcome in patients during and after therapy. Everyday food ingredients contain multiple drug-like molecules that can potentially prevent or beat diseases. For example, it is estimated that up to half of oncological diseases can be prevented by dietary choices. The wide adoption of tailored health-promoting diets potentially has a revolutionary impact on the population wellbeing and long-term sustainability of the healthcare systems. However, due to an exponentially large number of combinations of the ingredients, their sourcing, processing, preparation, and preservation methods, it is virtually impossible to use traditional experimental approaches to optimise the health-promoting molecular profiles of foods. Hyperfoods will use novel graph-based ML methods to provide the technological capabilities for the computational discovery and design of personalised nutrition. We will explore the commercial opportunities of our technology for currently unmet business needs in global health, in particular cancer treatments.
Campo scientifico
Programma(i)
Argomento(i)
Meccanismo di finanziamento
ERC-POC - Proof of Concept GrantIstituzione ospitante
SW7 2AZ LONDON
Regno Unito