Descripción del proyecto
Reforzar la capacidad de los niños para luchar contra el cáncer
Se ha observado que caminar, correr, andar en bici, nadar y muchos otros tipos de actividad física reducen el riesgo de cáncer. Del mismo modo, la morbilidad durante el tratamiento antineoplásico aumenta debido a la inactividad física, así como por la fatiga asociada al cáncer y la reducción de la calidad de vida relacionada con la salud. En este contexto, la oncología del ejercicio (actividad física adaptada a pacientes con cáncer) es una intervención sanitaria prometedora y que cuenta con un reconocimiento cada vez mayor. Pese a que la oncología del ejercicio ha demostrado unos efectos notables sobre la tolerancia y la tasa de finalización de tratamientos antineoplásicos en adultos, carecemos de datos sólidos sobre la eficacia del ejercicio en el caso de los niños. El proyecto financiado con fondos europeos FORTEe evaluará una intervención de ejercicio personalizado y estandarizado para niños y adolescentes sometidos a un tratamiento antineoplásico.
Objetivo
Cancer is the first leading cause of death by non-communicable diseases in children in Europe. During cancer treatment, patients’ morbidity is increased due to physical inactivity, cancer-related fatigue (CRF) and reduced health-related quality of life (HRQoL). Adapted exercise training in cancer patients, called exercise oncology, is an increasingly recognised, promising health care intervention. In adults, exercise oncology revealed notable effects on tolerance and completion rate of cancer treatment. However, in childhood cancer patients, strong evidence for exercise efficiency is lacking. Thus, precision exercise training is not part of standard care in paediatric oncology and does not reach the majority of patients. By pooling the leading expertise on a European and cross-Atlantic level, the FORTEe project aims to evaluate a personalised and standardised exercise intervention for children and adolescents undergoing anti-cancer treatment. In the randomised, controlled FORTEe trial, high evidence for an innovative, patient-centred exercise treatment will be generated. FORTEe promotes exercise oncology that aims at making patients “stronger to fight childhood cancer”. Supervised exercise training intents to increase muscle strength and reduce muscular atrophy due to bedrest. CRF and HRQoL can be improved and in the future, these benefits may help to fight childhood cancer by increasing therapy efficiency and survival rate. Within the project, digital, innovative technologies such as augmented reality will be developed and applied to make the exercise training more effective, age-adapted and personalised. Moreover, FORTEe will stimulate translational research to provide access to paediatric exercise oncology as a new health care intervention. As a progress beyond the current state-of-the-art, FORTEe has the ambition to implement paediatric exercise oncology as an evidence-based standard in clinical care for all childhood cancer patients across the EU and beyond.
Ámbito científico
Palabras clave
Programa(s)
Convocatoria de propuestas
Consulte otros proyectos de esta convocatoriaConvocatoria de subcontratación
H2020-SC1-2020-Two-Stage-RTD
Régimen de financiación
RIA - Research and Innovation actionCoordinador
55131 Mainz
Alemania