Description du projet
Renforcer les enfants pour les aider à lutter contre le cancer
La pratique de la marcher, de la course, du vélo, de la natation et tant d’autres types d’activité physique ont été associées à une réduction du risque de cancer. De même, pendant le traitement du cancer, la morbidité augmente en raison de l’inactivité physique, tout comme la fatigue liée au cancer, ce qui implique une qualité de vie réduite sur le plan de la santé. Dans ce contexte, l’oncologie par l’exercice physique (entraînement d’activité physique adapté aux patients atteints de cancer) bénéficie d’une reconnaissance grandissante, et constitue une intervention médicale prometteuse. Bien que l’oncologie par l’exercice physique ait révélé des effets notables sur la tolérance et le taux de réussite des traitements contre le cancer chez les adultes, il manque des preuves solides de l’efficacité de cette approche chez l’enfant. Le projet FORTEe, financé par l’UE, compte évaluer une intervention personnalisée et standardisée d’activité physique pour les enfants et les adolescents soumis à un traitement anticancéreux.
Objectif
Cancer is the first leading cause of death by non-communicable diseases in children in Europe. During cancer treatment, patients’ morbidity is increased due to physical inactivity, cancer-related fatigue (CRF) and reduced health-related quality of life (HRQoL). Adapted exercise training in cancer patients, called exercise oncology, is an increasingly recognised, promising health care intervention. In adults, exercise oncology revealed notable effects on tolerance and completion rate of cancer treatment. However, in childhood cancer patients, strong evidence for exercise efficiency is lacking. Thus, precision exercise training is not part of standard care in paediatric oncology and does not reach the majority of patients. By pooling the leading expertise on a European and cross-Atlantic level, the FORTEe project aims to evaluate a personalised and standardised exercise intervention for children and adolescents undergoing anti-cancer treatment. In the randomised, controlled FORTEe trial, high evidence for an innovative, patient-centred exercise treatment will be generated. FORTEe promotes exercise oncology that aims at making patients “stronger to fight childhood cancer”. Supervised exercise training intents to increase muscle strength and reduce muscular atrophy due to bedrest. CRF and HRQoL can be improved and in the future, these benefits may help to fight childhood cancer by increasing therapy efficiency and survival rate. Within the project, digital, innovative technologies such as augmented reality will be developed and applied to make the exercise training more effective, age-adapted and personalised. Moreover, FORTEe will stimulate translational research to provide access to paediatric exercise oncology as a new health care intervention. As a progress beyond the current state-of-the-art, FORTEe has the ambition to implement paediatric exercise oncology as an evidence-based standard in clinical care for all childhood cancer patients across the EU and beyond.
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RIA - Research and Innovation actionCoordinateur
55131 Mainz
Allemagne