Radiation risk appraisal for detrimental effects from medical exposure during management of patients with lymphoma or brain tumour

Informations projet

SINFONIA

N° de convention de subvention: 945196

DOI

10.3030/945196

Projet clôturé

Date de signature de la CE 14 Mai 2020

Date de début 1 Septembre 2020

Date de fin 31 Août 2024

Financé au titre de

• Euratom

Coût total

€ 5 999 998,75

Contribution de l’UE

€ 5 999 997,50

Coordonné par

EIBIR GEMEINNUTZIGE GMBH ZUR FORDERUNG DER ERFORSCHUNG DER BIOMEDIZINISCHEN BILDGEBUNG
Austria

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (22)

Report on cumulative doses and risks of 100 patients with lymphoma and brain tumours in a retrospective patient study
Methodology of an advanced computational approach and generation of new dose data for comforters in NUM
Report on recommendations from the SINFONIA panels on diagnostic radiology, nuclear medicine and radiation therapy
New dose data for specific procedures of staff in NUM
Requirements and design of the prototype architecture
Report on training courses for SINFONIA collaborators
Individual mutation levels induced by RT

Report describing stable aberration frequencies in PBL of patients undergoing RT.

Factors that influence the risk of SMN

Report summarising factors that influence the risk of SMN and optimal methods of risk transfer

Final report on dissemination activities
Radiation sensitivity biomarker for SMN

Report comparing DNA repair capacities of patients with primary and secondary cancers.

Factsheets and other information for the general public on doses from medical exposure and their impact on the risk for patients
Genetic biomarker for SMN

Report comparing SNP in patients with primary and secondary cancers.

Radionuclide dispersion simulations results
Report on dosimetry, radiobiology and radiation protection education in the field of medical imaging and radiation oncology

Report on dosimetry radiobiology and radiation protection education in the field of medical imaging and radiation oncology

Intermediate report on SINFONIA dissemination activities
Platform description, data model and protocols

Platform description data model and protocols

Context-aware integrated training module
Human, biota and aquatic biota study report

Human biota and aquatic biota study report

Final platform and algorithms integration
Field survey of staff dosimetry practice in proton radiotherapy centres
Updated Communication and Dissemination Plan and updated video
Methodological report on the development of a system for personalised dosimetry to account for in-field and out-of-field organ exposure from scatter dose during photon-based therapy, neutron-radiation and imaging in proton therapy

Methodological report on the development of a system for personalised dosimetry to account for infield and outoffield organ exposure from scatter dose during photonbased therapy neutronradiation and imaging in proton therapy

Other (5)

Software tool on personalised dosimetry in radiological imaging and deep-learning guided algorithms
Software tool on personalised dosimetry in PET-CT and deep learning-guided algorithms for automated construction of computational models
Software tool for risk appraisal using doses from radiological, nuclear medicine and radiation therapy procedures
Interactive MOOC on clinical dosimetry radiation risk analysis
Software tool on personalised dosimetry in photon-based radiation therapy imaging and deep-learning-guided algorithms

Publications

Peer reviewed articles (29)

Real-time, acquisition parameter-free voxel-wise patient-specific Monte Carlo dose reconstruction in whole-body CT scanning using deep neural networks

Auteurs: Yazdan Salimi; Azadeh Akhavanallaf; Zahra Mansouri; Isaac Shiri; Habib Zaidi
Publié dans: European Radiology 2023, Numéro 2, 2023, ISSN 1432-1084
Éditeur: Springer
DOI: 10.1007/s00330-023-09839-y

Impact of medical radionuclide discharges on people and the environment

Auteurs: J. Vives i Batlle, L. Sweeck, F. Fiengo Pérez
Publié dans: Journal of Environmental Radioactivity, Numéro 272, 2024, Page(s) 107362, ISSN 0265-931X
Éditeur: Elsevier BV
DOI: 10.1016/j.jenvrad.2023.107362

Rapid estimation of patient-specific organ doses using a deep learning network

Auteurs: Myronakis M, Stratakis J, Damilakis J
Publié dans: Medical Physics, Numéro 2023;1–9, 2023, ISSN 0094-2405
Éditeur: American Association of Physicists in Medicine
DOI: 10.1002/mp.16356

Deep transformer-based personalized dosimetry from SPECT/CT images: a hybrid approach for [177Lu]Lu-DOTATATE radiopharmaceutical therapy

Auteurs: Zahra Mansouri, Yazdan Salimi, Azadeh Akhavanallaf, Isaac Shiri, Eliluane Pirazzo Andrade Teixeira, Xinchi Hou, Jean-Mathieu Beauregard, Arman Rahmim, Habib Zaidi
Publié dans: European Journal of Nuclear Medicine and Molecular Imaging, Numéro 51, 2024, Page(s) 1516-1529, ISSN 1619-7070
Éditeur: Springer Verlag
DOI: 10.1007/s00259-024-06618-9

Range-shifter effects on the stray field in proton therapy measured with the variance-covariance method

Auteurs: Eliasson L, Lillhök J, Bäck T, Billnert-Maróti R, Dasu A, Liszka M
Publié dans: Frontiers in Oncology, Numéro 2022 Aug 2;12:882230., 2022, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.882230

Peripheral organ equivalent dose estimation procedure in proton therapy

Auteurs: Domingo C, Lagares JI, Romero-Expósito M, Sánchez-Nieto B, Nieto-Camero JJ, Terrón JA, Irazola L, Dasu A, Sánchez-Doblado F
Publié dans: Frontiers in Oncology, Numéro 2022 May 25;12:882476, 2022, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.882476

Medical applications of ionizing radiation and radiation protection for European patients, population and environment

Auteurs: Thierry-Chef, Isabelle; Cardis, Elisabeth; Damilakis, John; Frija, Guy; Hierath, Monika; Hoeschen, Christop; EURAMED ROCC-N-ROLL consortia members
Publié dans: EPJ Nuclear Sci. Technol., Numéro 8, 44, 2022, ISSN 2491-9292
Éditeur: EDP SCIENCES S A
DOI: 10.1051/epjn/2022044

Fully automated explainable abdominal CT contrast media phase classification using organ segmentation and machine learning

Auteurs: Yazdan Salimi, Zahra Mansouri, Ghasem Hajianfar, Amirhossein Sanaat, Isaac Shiri, Habib Zaidi
Publié dans: Medical Physics, Numéro 51, 2024, Page(s) 4095-4104, ISSN 0094-2405
Éditeur: American Association of Physicists in Medicine
DOI: 10.1002/mp.17076

Radiation exposure assessment of nuclear medicine staff administering [177Lu]Lu-DOTA-TATE with active and passive dosimetry

Auteurs: Mercedes Riveira-Martin, Lara Struelens, José Muñoz Iglesias, Werner Schoonjans, Olga Tabuenca, José Manuel Nogueiras, Francisco Javier Salvador Gómez, Antonio López Medina
Publié dans: EJNMMI Physics, Numéro 10, 2023, ISSN 2197-7364
Éditeur: Springer Verlag
DOI: 10.1186/s40658-023-00592-1

Prevención de la exposición ocupacional a la radiación del personal de enfermería de Medicina Nuclear

Auteurs: Interview with Riveira-Martin M
Publié dans: Archivos de Prevención de Riesgos Laborales, Numéro 2023;26(3):34-38, 2023, ISSN 1138-9672
Éditeur: Societat Catalana de Seguretat i Medicina del Treball (SCSMT)
DOI: 10.12961/aprl.2023.26.03.08

Range shifter contribution to neutron exposure of patients undergoing proton pencil beam scanning

Auteurs: Maite Romero‐Expósito, Malgorzata Liszka, Athanasia Christou, Iuliana Toma‐Dasu, Alexandru Dasu
Publié dans: Medical Physics, Numéro 51, 2024, Page(s) 5099-5108, ISSN 0094-2405
Éditeur: American Association of Physicists in Medicine
DOI: 10.1002/mp.16897

Accuracy of patient-specific CT organ doses from Monte Carlo simulations: influence of CT-based voxel models

Auteurs: Gwenny Verfaillie, Jeff Rutten, Yves D’Asseler, Klaus Bacher
Publié dans: Physical and Engineering Sciences in Medicine, Numéro 47, 2024, Page(s) 989-1000, ISSN 2662-4729
Éditeur: Springer Verlag
DOI: 10.1007/s13246-024-01422-z

Organomics

Auteurs: Yazdan Salimi, Ghasem Hajianfar, Zahra Mansouri, Amirhosein Sanaat, Mehdi Amini, Isaac Shiri, Habib Zaidi
Publié dans: Clinical Nuclear Medicine, Numéro 49, 2024, Page(s) 899-908, ISSN 0363-9762
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/rlu.0000000000005400

Deep learning-based fully automated Z-axis coverage range definition from scout scans to eliminate overscanning in chest CT imaging

Auteurs: Yazdan Salimi; Isaac Shiri; Azadeh Akhavanallaf; Zahra Mansouri; Abdollah Saberi Manesh; Amirhossein Sanaat; Masoumeh Pakbin; Dariush Askari; Saleh Sandoughdaran; Ehsan Sharifipour; Hossein Arabi; Habib Zaidi
Publié dans: Insights into Imaging, Vol 12, Iss 1, Pp 1-16 (2021), Numéro 1, 2021, ISSN 1869-4101
Éditeur: Springer Science and Business Media Deutschland GmbH
DOI: 10.1186/s13244-021-01105-3

Explainable AI for automated respiratory misalignment detection in PET/CT imaging

Auteurs: Yazdan Salimi, Zahra Mansouri, Mehdi Amini, Ismini Mainta, Habib Zaidi
Publié dans: Physics in Medicine & Biology, Numéro 69, 2024, ISSN 0031-9155
Éditeur: Institute of Physics Publishing
DOI: 10.1088/1361-6560/ad8857

Joint EURADOS-EANM initiative for an advanced computational framework for the assessment of external dose rates from nuclear medicine patients

Auteurs: Lara Struelens, Christelle Huet, David Broggio, Jérémie Dabin, Laurent Desorgher, Augusto Giussani, Wei Bo Li, Dietmar Nosske, Yi-Kang Lee, Lidia Cunha, Maria J. R. Carapinha, Mario Medvedec, Peter Covens
Publié dans: EJNMMI Physics, Numéro 11, 2024, ISSN 2197-7364
Éditeur: Springer Verlag
DOI: 10.1186/s40658-024-00638-y

The role of biomarkers and dosimetry parameters in overall and progression free survival prediction for patients treated with personalized 90Y glass microspheres SIRT: a preliminary machine learning study

Auteurs: Zahra Mansouri, Yazdan Salimi, Ghasem Hajianfar, Nicola Bianchetto Wolf, Luisa Knappe, Genti Xhepa, Adrien Gleyzolle, Alexis Ricoeur, Valentina Garibotto, Ismini Mainta, Habib Zaidi
Publié dans: European Journal of Nuclear Medicine and Molecular Imaging, 2024, ISSN 1619-7070
Éditeur: Springer Verlag
DOI: 10.1007/s00259-024-06805-8

Enhancing precision: A predictive model for ¹⁷⁷Lu-DOTATATE treatment response in neuroendocrine tumors using quantitative ⁶⁸Ga-DOTATATE PET and clinicopathological biomarkers

Auteurs: Azadeh Akhavanallaf, Sonal Joshi, Arathi Mohan, Francis P Worden, John C Krauss, Habib Zaidi, Kirk Frey, Krithika Suresh, Yuni K Dewaraja, Ka Kit Wong
Publié dans: Theranostics, Numéro 14, 2024, Page(s) 3708-3718, ISSN 1838-7640
Éditeur: Ivyspring International Publisher
DOI: 10.7150/thno.98053

Effect of Spectral Filtering and Segmental X-ray Tube Current Switch-Off on Interventionalist’s Scatter Exposure during CT Fluoroscopy

Auteurs: Oliver S. Grosser, Martin Volk, Marilena Georgiades, Daniel Punzet, Bahaa Alsawalhi, Dennis Kupitz, Jazan Omari, Heiko Wissel, Michael C. Kreissl, Georg Rose, Maciej Pech
Publié dans: Bioengineering, Numéro 11, 2024, Page(s) 838, ISSN 2306-5354
Éditeur: MDPI
DOI: 10.3390/bioengineering11080838

Determining Out-of-Field Doses and Second Cancer Risk From Proton Therapy in Young Patients—An Overview

Auteurs: Romero-Expósito M, Toma-Dasu I, Dasu A
Publié dans: Frontiers in Oncology, Numéro 2022 May 31;12:892078, 2022, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.892078

Fully automated accurate patient positioning in computed tomography using anterior–posterior localizer images and a deep neural network: a dual-center study

Auteurs: Yazdan Salimi; Isaac Shiri; Azadeh Akavanallaf; Zahra Mansouri; Hossein Arabi; Habib Zaidi
Publié dans: European Radiology 2023, Numéro 2023 May;33(5), 2023, Page(s) 3243-3252, ISSN 1432-1084
Éditeur: Springer
DOI: 10.1007/s00330-023-09424-3

Occupational radiation exposure assessment during the management of [68Ga]Ga-DOTA-TOC

Auteurs: Riveira-Martin M, Struelens L, Schoonjans W, Sánchez-Díaz I, Muñoz Iglesias J, Ferreira Dávila Ó, Salvador Gómez FJ, Salgado Fernández M, López Medina A
Publié dans: EJNMMI Physics, Numéro 9, 75 (2022), 2022, ISSN 2197-7364
Éditeur: Springer
DOI: 10.1186/s40658-022-00505-8

Influence of X-ray spectrum and bowtie filter characterisation on the accuracy of Monte Carlo simulated organ doses: Validation in a whole-body CT scanning mode

Auteurs: Gwenny Verfaillie, Jeff Rutten, Lore Dewulf, Yves D’Asseler, Klaus Bacher
Publié dans: Physica Medica, Numéro 127, 2024, Page(s) 104837, ISSN 1120-1797
Éditeur: Istituti Editoriali e Poligrafici Internazionali
DOI: 10.1016/j.ejmp.2024.104837

Predictive value of 99mTc-MAA-based dosimetry in personalized 90Y-SIRT planning for liver malignancies

Auteurs: Mercedes Riveira-Martin; Azadeh Akhavanallaf; Zahra Mansouri; Nicola Bianchetto Wolf; Yazdan Salimi; Alexis Ricoeur; Ismini Mainta; Valentina Garibotto; Antonio López Medina; Habib Zaidi
Publié dans: EJNMMI research, Numéro vol. 13, no. 1 (2023) 63, 2023, ISSN 2191-219X
Éditeur: Springer Berlin
DOI: 10.1186/s13550-023-01011-3

Digital phantom versus patient‐specific radiation dosimetry in adult routine thorax CT examinations

Auteurs: Antonios E. Papadakis, Vassiliki Giannakaki, John Stratakis, Marios Myronakis, Habib Zaidi, John Damilakis
Publié dans: Journal of Applied Clinical Medical Physics, Numéro 25, 2024, ISSN 1526-9914
Éditeur: American Institute of Physics
DOI: 10.1002/acm2.14389

Object and person tracking systems to enable extremity dosimetry in nuclear medicine using computational methods

Auteurs: Daniel Santiago Rondón, Pasquale Lombardo, Mahmoud Abdelrahman, Lara Struelens, Filip Vanhavere, Niki Bergans
Publié dans: Journal of Radiological Protection, Numéro 44, 2024, Page(s) 021524, ISSN 0952-4746
Éditeur: Institute of Physics Publishing
DOI: 10.1088/1361-6498/ad53d5

The predictive value of pretherapy [ 68Ga]Ga‑DOTA‑TATE PET and biomarkers in [ 177Lu]Lu‑PRRT tumor dosimetry

Auteurs: Habib Zaidi
Publié dans: Eur J Nucl Med Mol Imaging, Numéro 50, 2023, Page(s) 2984–2996 (2023), ISSN 1619-7070
Éditeur: Springer Verlag
DOI: 10.1007/s00259-023-06252-x

An efficient dual-domain deep learning network for sparse-view CT reconstruction

Auteurs: Chang Sun, Yazdan Salimi, Neroladaki Angeliki, Sana Boudabbous, Habib Zaidi
Publié dans: Computer Methods and Programs in Biomedicine, Numéro 256, 2024, Page(s) 108376, ISSN 0169-2607
Éditeur: Elsevier BV
DOI: 10.1016/j.cmpb.2024.108376

Deep Learning-based calculation of patient size and attenuation surrogates from localizer Image: Toward personalized chest CT protocol optimization

Auteurs: Salimi Y, Shiri I, Akhavanallaf A, Mansouri Z, Sanaat A, Pakbin M, Ghasemian M, Arabi H, Zaidi H
Publié dans: European Journal of Radiology, Numéro Volume 157, 110602, 2022, ISSN 0720-048X
Éditeur: Elsevier BV
DOI: 10.1016/j.ejrad.2022.110602

Thesis and dissertations (2)

Dosimetría personalizada a trabajadores y pacientes en procedimientos de Medicina Nuclear con nuevos radiofármacos teranósticos

Auteurs: Mercedes del Carmen Riveira Martín
Publié dans: 2024
Éditeur: Universidad Complutense de Madrid, Facultad de Medicina

Strategies for radiation dose calculation and optimization in diagnostic and therapeutic nuclear medicine procedure

Auteurs: Akhavanallaf A
Publié dans: 2023
Éditeur: UNIGE
DOI: 10.13097/archive-ouverte/unige:168338

Conference proceedings (4)

Real-time voxelwise patient-specific Monte Carlo dose reconstruction in whole-body CT scan images using deep neural network

Auteurs: Salimi Y, Akhavanallaf A, Mansouri Z, Shiri I, Zaidi H
Publié dans: IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2022
Éditeur: IEEE

Fully automated multi-organ segmentation in CT images via deep neural networks

Auteurs: Salimi Y, Shiri I, Mansouri Z, Zaidi H
Publié dans: IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2022
Éditeur: IEEE

Head and neck cancer overall survival prognostication using dosiomics features and random survival Forest algorithm

Auteurs: Mansouri Z, Salimi Y, Amini M, Hajianfar G, Oveisi M, Shiri I, Zaidi H
Publié dans: IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2022
Éditeur: IEEE

Advancing continuous education in the radiology department: case example through a novel software that quantifies repeated scans in CT

Auteurs: Niki Fitousi, Tom Van Herpe, Bojan Arnaudovski, Thomas De Waelheyns, Hilde Bosmans, Jurgen Jacobs
Publié dans: Proceedings of the European Radiation Protection Week 2022, 2022
Éditeur: Centro de Ciências e Tecnologias Nucleares