Central Repository for Digital Pathology

Objective

BIGPICTURE, a pathology-led consortium, has the vision to become the catalyst in digital transformation in Pathology. Our mission is to create the first European GDPR compliant platform, in which both quality-controlled Whole Slide Imaging (WSI) data and advanced Artificial intelligence (AI) algorithms will exist. The BIGPICTURE platform will be built on existing assets of ELIXIR EU data infrastructure, including the federated European Genome-phenome Archive (EGA) technology for managing the exchange of confidential information between contributors and users. The consortium will use Cytomine, an established open-source, cross-platform framework to develop unique tools for access to WSI, including annotations and visualisation of algorithm results, while we will develop new and generic models to facilitate AI development and mining of WSI data. By engaging and building consensus with all the relevant stakeholders, we will contribute to the development of a regulatory framework for digital slides and AI-based methods. Finally, BIGPICTURE envisions sustainability of its platform through a community- based model which relies on reciprocity, value creation and inclusiveness.
To achieve our vision, we have brought together Europe’s leaders in the field of computational pathology who have access to national and European high-performance computing infrastructures as well as Europe’s fully digitalised pathology departments. Additionally, the consortium has currently access to approximately 4.5 million clinical WSI covering a wider range of indications through 17 partners and 23 third parties from the largest European and international pathology and trial groups. Our consortium is further strengthened by the presence of the European Society of Pathology, Digital Pathology Association, FDA and 9 SMEs as partners, while we are further supported by professional societies, and patient advocates.

Field of science

• /medical and health sciences/basic medicine/pathology
• /natural sciences/computer and information sciences/artificial intelligence

Programme(s)

• H2020-EU.3.1.7. - Innovative Medicines Initiative 2 (IMI2)

Topic(s)

• IMI2-2019-18-01 - Central repository of digital pathology slides to support the development of artificial intelligence tools

Call for proposal

H2020-JTI-IMI2-2019-18-two-stage
See other projects for this call

Funding Scheme

IMI2-RIA - Research and Innovation action

Coordinator

STICHTING KATHOLIEKE UNIVERSITEIT

Address

Geert Grooteplein Noord 9
6525 EZ Nijmegen
Netherlands

Activity type

Higher or Secondary Education Establishments

EU contribution

€ 8 564 398,75

Participants (44)

LINKOPINGS UNIVERSITET

Sweden

EU contribution

€ 2 200 000

Address

Campus Valla
581 83 Linkoping

Activity type

Higher or Secondary Education Establishments

THE LEEDS TEACHING HOSPITALS NATIONAL HEALTH SERVICE TRUST

United Kingdom

EU contribution

€ 950 150

Address

St James's University Hospital, Beckett Street
LS9 7TF Leeds

Activity type

Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)

UNIVERSITAIR MEDISCH CENTRUM UTRECHT

Netherlands

EU contribution

€ 600 000

Address

Heidelberglaan 100
3584 CX Utrecht

Activity type

Higher or Secondary Education Establishments

CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY

Finland

EU contribution

€ 3 966 875

Address

Keilaranta 14
02101 Espoo

Activity type

Other

UPPSALA UNIVERSITET

Sweden

EU contribution

€ 2 625 000

Address

Von Kraemers Alle 4
751 05 Uppsala

Activity type

Higher or Secondary Education Establishments

FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

Germany

EU contribution

€ 240 006,25

Address

Hansastrasse 27C
80686 Munchen

Activity type

Research Organisations

HAUTE ECOLE SPECIALISEE DE SUISSE OCCIDENTALE

Switzerland

EU contribution

€ 300 000

Address

Route De Moutier 14
2800 Delemont

Activity type

Higher or Secondary Education Establishments

TECHNISCHE UNIVERSITEIT EINDHOVEN

Netherlands

EU contribution

€ 240 000

Address

Groene Loper 3
5612 AE Eindhoven

Activity type

Higher or Secondary Education Establishments

AZIENDA OSPEDALIERA PER L EMERGENZA CANNIZZARO

Italy

EU contribution

€ 71 875

Address

Via Messina 829
95126 Catania

Activity type

Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)

THE UNIVERSITY OF WARWICK

United Kingdom

EU contribution

€ 399 982,50

Address

Kirby Corner Road - University House
CV4 8UW Coventry

Activity type

Higher or Secondary Education Establishments

TECHNISCHE UNIVERSITAET MUENCHEN

Germany

EU contribution

€ 312 000

Address

Arcisstrasse 21
80333 Muenchen

Activity type

Higher or Secondary Education Establishments

MEDIZINISCHE UNIVERSITAT GRAZ

Austria

EU contribution

€ 232 000

Address

Auenbruggerplatz 2
8036 Graz

Activity type

Higher or Secondary Education Establishments

INSTITUT PASTEUR

France

EU contribution

€ 378 125

Address

Rue Du Docteur Roux 25-28
75724 Paris Cedex 15

Activity type

Research Organisations

UNIVERSITE DE LIEGE

Belgium

EU contribution

€ 1 625 375

Address

Place Du 20 Aout 7
4000 Liege

Activity type

Higher or Secondary Education Establishments

SEMMELWEIS EGYETEM

Hungary

EU contribution

€ 72 000

Address

Ulloi Utca 26
1085 Budapest

Activity type

Higher or Secondary Education Establishments

STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS

Netherlands

EU contribution

€ 200 000

Address

Plesmanlaan 121
1066 CX Amsterdam

Activity type

Research Organisations

BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC)

Austria

EU contribution

€ 380 000

Address

Neue Stiftingtalstrasse 2/B/6
8010 Graz

Activity type

Research Organisations

DIN DEUTSCHES INSTITUT FUER NORMUNG E.V.

Germany

EU contribution

€ 98 412,50

Address

Burggrafenstrasse 6
10787 Berlin

Activity type

Other

OSTERGOTLANDS LANS LANDSTING

Sweden

EU contribution

€ 600 000

Address

Larsgatan 49B
581 91 Linkoping

Activity type

Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)

MEDIZINISCHE UNIVERSITAET WIEN

Austria

EU contribution

€ 600 000

Address

Spitalgasse 23
1090 Wien

Activity type

Higher or Secondary Education Establishments

THE EUROPEAN INSTITUTE FOR INNOVATION THROUGH HEALTH DATA

Belgium

EU contribution

€ 60 000

Address

Oude Mechelsestraat 165
1853 Strombeek-bever

Activity type

Research Organisations

HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ

Finland

EU contribution

€ 900 000

Address

Stenbackinkatu 9
00029 Helsinki

Activity type

Research Organisations

PHILIPPS UNIVERSITAET MARBURG

Germany

EU contribution

€ 600 000

Address

Biegenstrasse 10
35037 Marburg

Activity type

Higher or Secondary Education Establishments

EUROPEAN SOCIETY OF PATHOLOGY

Belgium

EU contribution

€ 60 000

Address

Rue Bara 6
1070 Bruxelles

Activity type

Other

DIGITAL PATHOLOGY ASSOCIATION INC

United States

EU contribution

€ 12 000

Address

370 Medical Drive Suite A
46032 Carmel

Activity type

Other

GBG FORSCHUNGS GMBH

Germany

EU contribution

€ 72 000

Address

Martin Behaim Strasse 12
63263 Neu-isenburg

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

TTOPSTART BV

Netherlands

EU contribution

€ 160 000

Address

Euclideslaan 1
3584 BL Utrecht

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

SECTRA AB

Sweden

EU contribution

€ 196 875

Address

Teknikringen 20
58330 Linkoping

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

CYTOMINE

Belgium

EU contribution

€ 518 750

Address

Rue Du Bois Saint-jean 15 Boite 1
4102 Seraing

Activity type

Other

STICHTING LYGATURE

Netherlands

EU contribution

€ 1 724 000

Address

Jaarbeursplein 6
3521 AL Utrecht

Activity type

Other

OWKIN FRANCE

France

EU contribution

€ 400 000

Address

12 Rue Martel
75010 Paris

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

DECIPHEX LIMITED

Ireland

EU contribution

€ 2 450 000

Address

7 Garrai Na Gcrann
Mornington Meath

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

PHIT BV

Netherlands

EU contribution

€ 270 000

Address

Mercatorlaan 1200
3528 BL Utrecht

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

TIME.LEX

Belgium

EU contribution

€ 240 000

Address

Joseph Stevensstraat 7
1000 Brussel

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

NOVARTIS PHARMA AG

Switzerland

EU contribution

€ 0

Address

Lichtstrasse 35
4056 Basel

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

JANSSEN PHARMACEUTICA NV

Belgium

EU contribution

€ 0

Address

Turnhoutseweg 30
2340 Beerse

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

BAYER AKTIENGESELLSCHAFT

Germany

EU contribution

€ 0

Address

Kaiser-wilhelm-allee 1
51373 Leverkusen

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

BOEHRINGER INGELHEIM INTERNATIONALGMBH

Germany

EU contribution

€ 0

Address

Binger Strasse
55218 Ingelheim

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

NOVO NORDISK A/S

Denmark

EU contribution

€ 0

Address

Novo Alle 1
2880 Bagsvaerd

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

PFIZER LIMITED

United Kingdom

EU contribution

€ 0

Address

Ramsgate Road
CT13 9NJ Sandwich

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

F. HOFFMANN-LA ROCHE AG

Switzerland

EU contribution

€ 0

Address

Grenzacherstrasse 124
4070 Basel

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT

France

EU contribution

€ 0

Address

Pierre Brossolette 1
91380 Chilly Mazarin

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

INSTITUT DE RECHERCHES INTERNATIONALES SERVIER IRIS

France

EU contribution

€ 0

Address

Rue Carnot 50
92284 Courbevoie

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

UCB BIOPHARMA SRL

Belgium

EU contribution

€ 0

Address

Allee De La Recherche 60
1070 Bruxelles

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)