Thrombotic MEMOry-Linking a break in tolerance to platelets to REthrombosis

Project Information

T-MEMORE

Grant agreement ID: 947611

DOI

10.3030/947611

EC signature date 27 November 2020

Start date 1 December 2020

End date 30 November 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 483 145,00

EU contribution

€ 1 483 145,00

Coordinated by

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (10)

Interplay between inflammation and thrombosis in cardiovascular pathology

Author(s): Konstantin Stark, Steffen Massberg
Published in: Nature reviews Cardiology, 2021, ISSN 1759-5002
Publisher: Nature Publishing Group
DOI: 10.1038/s41569-021-00552-1

Thromboinflammation in long COVID—the elusive key to postinfection sequelae?

Author(s): Leo Nicolai, Rainer Kaiser, Konstantin Stark
Published in: Journal of Thrombosis and Haemostasis, 2023, ISSN 1538-7836
Publisher: John Wiley
DOI: 10.1016/j.jtha.2023.04.039

Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation

Author(s): Pekayvaz K, Gold C, Hoseinpour P, Engel A, Martinez-Navarro A, Eivers L, Coletti R, Joppich M, Dionísio F, Kaiser R, Tomas L, Janjic A, Knott M, Mehari F, Polewka V, Kirschner M, Boda A, Nicolai L, Schulz H, Titova A, Kilani B, Lorenz M, Fingerle-Rowson G, Bucala R, Enard W, Zimmer R, Weber C, Libby P, Schulz C, Massberg S, Stark K.
Published in: Immunity, 2023, ISSN 1097-4180
Publisher: Cell Press
DOI: 10.1016/j.immuni.2023.08.002

Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection

Author(s): Kami Pekayvaz, Alexander Leunig, Rainer Kaiser, Markus Joppich, Sophia Brambs, Aleksandar Janjic, Oliver Popp, Daniel Nixdorf, Valeria Fumagalli, Nora Schmidt, Vivien Polewka, Afra Anjum, Viktoria Knottenberg, Luke Eivers, Lucas E. Wange, Christoph Gold, Marieluise Kirchner, Maximilian Muenchhoff, Johannes C. Hellmuth, Clemens Scherer, Raquel Rubio-Acero, Tabea Eser, Flora Deák, Kerstin Puchinger
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-28508-0

Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19

Author(s): Rainer Kaiser,1,2,3 Alexander Leunig,corresponding author1,2 Kami Pekayvaz,1,2,3 Oliver Popp,4,5 Markus Joppich,6 Vivien Polewka,1 Raphael Escaig,1 Afra Anjum,1 Marie-Louise Hoffknecht,1 Christoph Gold,1 Sophia Brambs,1 Anouk Engel,1 Sven Stockhausen,1,2 Viktoria Knottenberg,1 Anna Titova,1 Mohamed Haji,4,5 Clemens Scherer,1,2,3 Maximilian Muenchhoff,3,7,8 Johannes C. Hellmuth,3,9 Kathrin Saar,4,5
Published in: Blood, 2021, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1172/jci.insight.150862

Thromboinflammation in long COVID-the elusive key to postinfection sequelae?

Author(s): Leo Nicolai, Rainer Kaiser, Konstantin Stark
Published in: Journal of Thrombosis and Haemostasis, 2023, ISSN 1538-7836
Publisher: Elsevier

Intravital calcium imaging in myeloid leukocytes identifies calcium frequency spectra as indicators of functional states

Author(s): Mehari FT, Miller M, Pick R, Bader A, Pekayvaz K, Napoli M, Uhl B, Reichel CA, Sperandio M, Walzog B, Schulz C, Massberg S, Stark K
Published in: Science Signaling, 2022, ISSN 1945-0877
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scisignal.abe6909

Procoagulant platelet sentinels prevent inflammatory bleeding through GPIIBIIIA and GPVI

Author(s): Rainer Kaiser 1 , Raphael Escaig 1 , Jan Kranich 2 , Marie-Louise Hoffknecht 3 , Afra Anjum 3 , Vivien Polewka 3 , Magdalena Mader 4 , Wenbo Hu 2 , Larissa Belz 3 , Christoph Gold 4 , Anna Titova 4 , Michael Lorenz 5 , Kami Pekayvaz 1 , Stefan Kääb 1 , Florian Gaertner 6 , Konstantin Stark 1 , Thomas Brocker 2 , Steffen Massberg 1 , Leo Nicolai 1
Published in: Blood, 2021, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood.2021014914

Thrombocytopenia and splenic platelet directed immune responses after intravenous ChAdOx1 nCov-19 administration.

Author(s): "Leo Nicolai,1,2,#§ Alexander Leunig,1,2,#§ Kami Pekayvaz,1,2,#§ Max Esefeld,3 Afra Anjum,1 Justina Rath,3 Eva Riedlinger,1 Vincent Ehreiser,1,2 Magdalena Mader,1 Luke Eivers,1 Marie-Louise Hoffknecht,1 Zhe Zhang,1 Daniela Kugelmann,4 Dario Rossaro,1 Raphael Escaig,1 Rainer Kaiser,1,2 Vivien Polewka,1 Anna Titova,1 Tobias Petzold,1,2 Karsten Spiekermann,5 Matteo Iannacone,6 Thomas Thiele,3 Andre"
Published in: Blood, 2022, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood.2021014712

Differential Effects of Erythropoietin Administration and Overexpression on Venous Thrombosis in Mice.

Author(s): Stockhausen S, Kilani B, Schubert I, Steinsiek AL, Chandraratne S, Wendler F, Eivers L, von Brühl ML, Massberg S, Ott I, Stark K.
Published in: Thrombosis Haemostasis, 2023, ISSN 0340-6245
Publisher: Schattauer