Project description
Dissecting the mechanism of mRNA export from the nucleus
Transport in and out of the nucleus is a highly selective process carried out by a specific set of proteins. In terms of mRNA, it must undergo full processing and maturation in the nucleus before crossing the nuclear envelope. The EU-funded RNApaxport project aims to shed light on the mechanism of this mRNA transport specificity. In particular, scientists will investigate how a defined set of conserved proteins package and export all nuclear mRNA. For this purpose, they will examine the organisation, dynamics and function of key packaging factors. Insight into the role of mRNA length and sequence will help understand the complex mechanisms of gene expression.
Fields of science
Programme(s)
Topic(s)
Funding Scheme
ERC-STG - Starting Grant
Host institution
FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH
Net EU contribution
€ 1 500 000,00
Address
Campus-vienna-biocenter 1
1030 Wien
Austria
1030 Wien
Austria
See on map
Region
Wien Wien
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
Beneficiaries (1)
FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH
Austria
Net EU contribution
€ 1 500 000,00
Address
Campus-vienna-biocenter 1
1030 Wien
1030 Wien
See on map
Region
Wien Wien
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00