Improving our understanding of the evolutionary dynamics of pathogens
Understanding the rapid adaptation mechanisms of infectious pathogens is key to designing better management strategies. However, existing models often fail to explain these dynamics as the evolutionary processes causing these changes are largely unknown. The EU-funded EvoComBac project aims to address this challenge of evolutionary biology in the bacterial species Escherichia coli. To that end, it will develop a prospective cohort of 200 longitudinally followed healthy volunteers – the largest of its kind – and collect data to analyse and describe the ecology of Escherichia coli from within-host to population level. Ultimately, the project's work will lead to better predictions of evolutionary dynamics and better management policies for infectious pathogens.
Fields of science
Call for proposal
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