The hardships for life to become big – rethinking hypoxia as an evolutionary driver for the rise of complex multicellularity

Información del proyecto

ParadOX

Identificador del acuerdo de subvención: 949538

DOI

10.3030/949538

Fecha de la firma de la CE 8 Septiembre 2020

Fecha de inicio 1 Enero 2021

Fecha de finalización 31 Diciembre 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 500 000,00

Aportación de la UE

€ 1 500 000,00

Coordinado por

LUNDS UNIVERSITET
Sweden

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (19)

Sustained increases in atmospheric oxygen and marine productivity in the Neoproterozoic and Palaeozoic eras

Autores: Richard G. Stockey, Devon B. Cole, Una C. Farrell, Heda Agić, Thomas H. Boag, Jochen J. Brocks, Don E. Canfield, Meng Cheng, Peter W. Crockford, Huan Cui, Tais W. Dahl, Lucas Del Mouro, Keith Dewing, Stephen Q. Dornbos, Joseph F. Emmings, Robert R. Gaines, Timothy M. Gibson, Benjamin C. Gill, Geoffrey J. Gilleaudeau, Karin Goldberg, Romain Guilbaud, Galen Halverson, Emma U. Hammarlund, Kalev Hant
Publicado en: Nature Geoscience, Edición 17, 2024, Página(s) 667-674, ISSN 1752-0894
Editor: Nature Publishing Group
DOI: 10.1038/s41561-024-01479-1

Rapid marine oxygen variability: Driver of the Late Ordovician mass extinction

Autores: Nevin P Kozik, Seth A Young, Sean M Newby, Mu Liu, Daizhao Chen, Emma U Hammarlund, David PG Bond, Theodore R Them, Jeremy D Owens
Publicado en: Science Advances, 2022, ISSN 2375-2548
Editor: AAAS
DOI: 10.1126/sciadv.abn8345

“Hypoxic” Silurian oceans suggest early animals thrived in a low-O2 world

Autores: Emma R. Haxen, Niels H. Schovsbo, Arne T. Nielsen, Sylvain Richoz, David K. Loydell, Nicole R. Posth, Donald E. Canfield, Emma U. Hammarlund
Publicado en: Earth and Planetary Science Letters, Edición 622, 2024, Página(s) 118416, ISSN 0012-821X
Editor: Elsevier BV
DOI: 10.1016/j.epsl.2023.118416

Origin and evolution of animal multicellularity in the light of phylogenomics and cancer genetics

Autores: Florian Jacques, Etienne Baratchart, Kenneth J. Pienta & Emma U. Hammarlund
Publicado en: Medical Oncology, 2022, ISSN 1357-0560
Editor: Humana Press, Inc.
DOI: 10.1007/s12032-022-01740-w

Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation

Autores: Christopher Carroll, Auraya Manaprasertsak, Arthur Boffelli Castro, Hilda van den Bos, Diana C.J. Spierings, René Wardenaar, Anuraag Bukkuri, Niklas Engström, Etienne Baratchart, Minjun Yang, Andrea Biloglav, Charlie K. Cornwallis, Bertil Johansson, Catharina Hagerling, Marie Arsenian-Henriksson, Kajsa Paulsson, Sarah R. Amend, Sofie Mohlin, Floris Foijer, Alan McIntyre, Kenneth J. Pienta, Emma
Publicado en: Cancer Research Communications, Edición 4, 2024, Página(s) 691-705, ISSN 2767-9764
Editor: American Association for Cancer Research (AACR)
DOI: 10.1158/2767-9764.crc-23-0396

Sulfidic anoxia in the oceans during the Late Ordovician mass extinctions – insights from molybdenum and uranium isotopic global redox proxies

Autores: Tais W.Dahl, Emma U.Hammarlund, Christian Mac Ørum Rasmussen, David P.G.Bond, Donald E.Canfield
Publicado en: Earth-Science Reviews, 2021, ISSN 0012-8252
Editor: Elsevier BV
DOI: 10.1016/j.earscirev.2021.103748

The sedimentary geochemistry and paleoenvironments project

Autores: Úna C Farrell, Rifaat Samawi, Savitha Anjanappa, Roman Klykov, Oyeleye O Adeboye, Heda Agic, Anne‐Sofie C Ahm, Thomas H Boag, Fred Bowyer, Jochen J Brocks, Tessa N Brunoir, Donald E Canfield, Xiaoyan Chen, Meng Cheng, Matthew O Clarkson, Devon B Cole, David R Cordie, Peter W Crockford, Huan Cui, Tais W Dahl, Lucas D Mouro, Keith Dewing, Stephen Q Dornbos, Nadja Drabon, Julie A Dumoulin, Joseph
Publicado en: Geobiology, 2021, ISSN 1472-4669
Editor: Wiley-Blackwell
DOI: 10.1111/gbi.12462

Early Silurian δ13Corg excursions in the foreland basin of Baltica, both familiar and surprising

Autores: Emma U. Hammarlund, David K. Loydell, Arne T. Nielsen, Niels H. Schovsbo
Publicado en: Palaeogeography, Palaeoclimatology, Palaeoecology, Edición 526, 2023, Página(s) 126-135, ISSN 0031-0182
Editor: Elsevier BV
DOI: 10.1016/j.palaeo.2019.03.035

Hypoxia inducible factor‐2α importance for migration, proliferation, and self‐renewal of trunk neural crest cells

Autores: Camilla U. Niklasson, Elina Fredlund, Emanuela Monni, Jessica M. Lindvall, Zaal Kokaia, Emma U. Hammarlund, Marianne E. Bronner, Sofie Mohlin
Publicado en: Developmental Dynamics, 2021, ISSN 1058-8388
Editor: John Wiley & Sons Inc.
DOI: 10.1002/dvdy.253

Benthic diel oxygen variability and stress as potential drivers for animal diversification in the Neoproterozoic-Palaeozoic

Autores: Emma U. Hammarlund, Anuraag Bukkuri, Magnus D. Norling, Mazharul Islam, Nicole R. Posth, Etienne Baratchart, Christopher Carroll, Sarah R. Amend, Robert A. Gatenby, Kenneth J. Pienta, Joel S. Brown, Shanan E. Peters, Kasper Hancke
Publicado en: Nature Communications, Edición 16, 2025, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-025-57345-0

Tackling ongoing crises with collective evolutionary knowledge

Autores: Emma U. Hammarlund, Liselotte Jauffred, Nicole R. Posth, Karina K. Sand
Publicado en: Evolving Earth, Edición 2, 2024, Página(s) 100043, ISSN 2950-1172
Editor: Elsevier BV
DOI: 10.1016/j.eve.2024.100043

Oxygen-sensing mechanisms across eukaryotic kingdoms and their roles in complex multicellularity

Autores: Emma U. Hammarlund, Emily Flashman, Sofie Mohlin, Francesco Licausi
Publicado en: Science, 2020, ISSN 0036-8075
Editor: American Association for the Advancement of Science
DOI: 10.1126/science.aba3512

On the Origin of Information Dynamics in Early Life

Autores: Robert A. Gatenby, Jill Gallaher, Hemachander Subramanian, Emma U. Hammarlund, Christopher J. Whelan
Publicado en: Life, Edición 15, 2025, Página(s) 234, ISSN 2075-1729
Editor: MDPI AG
DOI: 10.3390/life15020234

Hypoxia Generated by Avian Embryo Growth Induces the HIF-α Response and Critical Vascularization

Autores: Christopher Carroll, Niklas Engström, Patrik F. Nilsson, Emma R. Haxen, Sofie Mohlin, Peter Berg, Ronnie N. Glud and Emma U. Hammarlund
Publicado en: Frontiers in Ecology and Evolution, 2021, ISSN 2296-701X
Editor: Frontiers in Ecology and Evolution
DOI: 10.3389/fevo.2021.675800

Roadmap to the study of gene and protein phylogeny and evolution—A practical guide

Autores: Florian Jacques, Paulina Bolivar, Kristian Pietras, Emma U Hammarlund
Publicado en: Plos One, 2023, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0279597

The contribution of evolvability to the <scp>eco‐evolutionary</scp> dynamics of competing species

Autores: Anuraag Bukkuri, Kenneth J. Pienta, Sarah R. Amend, Robert H. Austin, Emma U. Hammarlund, Joel S. Brown
Publicado en: Ecology and Evolution, Edición 13, 2023, ISSN 2045-7758
Editor: John Wiley and Sons Ltd
DOI: 10.1002/ece3.10591

Development of Iron Speciation Reference Materials for Palaeoredox Analysis

Autores: Lewis J. Alcott, Alexander J. Krause, Emma U. Hammarlund, Christian J. Bjerrum, Florian Scholz, Yijun Xiong, Andrew J. Hobson, Lesley Neve, Benjamin J. W. Mills, Christian März, Bernhard Schnetger, Andrey Bekker, Simon W. Poulton
Publicado en: Geostandards and Geoanalytical Research, Edición 44, 2023, Página(s) 581-591, ISSN 1639-4488
Editor: Association Scientifique pour la Geologie et ses Applications
DOI: 10.1111/ggr.12342

Redox dynamics of later Cambrian oceans

Autores: Benjamin C. Gill, Tais W. Dahl, Emma U. Hammarlund, Matthew A. LeRoy, Gwyneth W. Gordon, Donald E. Canfield, Ariel D. Anbar, Timothy W. Lyons
Publicado en: Palaeogeography, Palaeoclimatology, Palaeoecology, 2021, ISSN 0031-0182
Editor: Elsevier BV
DOI: 10.1016/j.palaeo.2021.110623

A life history model of the ecological and evolutionary dynamics of polyaneuploid cancer cells

Autores: Anuraag Bukkuri, Kenneth J. Pienta, Robert H. Austin, Emma U. Hammarlund, Sarah R. Amend & Joel S. Brown
Publicado en: Scientific Reports, 2022, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-022-18137-4