The hardships for life to become big – rethinking hypoxia as an evolutionary driver for the rise of complex multicellularity

Informazioni relative al progetto

ParadOX

ID dell’accordo di sovvenzione: 949538

DOI

10.3030/949538

Data della firma CE 8 Settembre 2020

Data di avvio 1 Gennaio 2021

Data di completamento 31 Dicembre 2025

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 500 000,00

Contributo UE

€ 1 500 000,00

Coordinato da

LUNDS UNIVERSITET
Sweden

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (19)

Sustained increases in atmospheric oxygen and marine productivity in the Neoproterozoic and Palaeozoic eras

Autori: Richard G. Stockey, Devon B. Cole, Una C. Farrell, Heda Agić, Thomas H. Boag, Jochen J. Brocks, Don E. Canfield, Meng Cheng, Peter W. Crockford, Huan Cui, Tais W. Dahl, Lucas Del Mouro, Keith Dewing, Stephen Q. Dornbos, Joseph F. Emmings, Robert R. Gaines, Timothy M. Gibson, Benjamin C. Gill, Geoffrey J. Gilleaudeau, Karin Goldberg, Romain Guilbaud, Galen Halverson, Emma U. Hammarlund, Kalev Hant
Pubblicato in: Nature Geoscience, Numero 17, 2024, Pagina/e 667-674, ISSN 1752-0894
Editore: Nature Publishing Group
DOI: 10.1038/s41561-024-01479-1

Rapid marine oxygen variability: Driver of the Late Ordovician mass extinction

Autori: Nevin P Kozik, Seth A Young, Sean M Newby, Mu Liu, Daizhao Chen, Emma U Hammarlund, David PG Bond, Theodore R Them, Jeremy D Owens
Pubblicato in: Science Advances, 2022, ISSN 2375-2548
Editore: AAAS
DOI: 10.1126/sciadv.abn8345

“Hypoxic” Silurian oceans suggest early animals thrived in a low-O2 world

Autori: Emma R. Haxen, Niels H. Schovsbo, Arne T. Nielsen, Sylvain Richoz, David K. Loydell, Nicole R. Posth, Donald E. Canfield, Emma U. Hammarlund
Pubblicato in: Earth and Planetary Science Letters, Numero 622, 2024, Pagina/e 118416, ISSN 0012-821X
Editore: Elsevier BV
DOI: 10.1016/j.epsl.2023.118416

Origin and evolution of animal multicellularity in the light of phylogenomics and cancer genetics

Autori: Florian Jacques, Etienne Baratchart, Kenneth J. Pienta & Emma U. Hammarlund
Pubblicato in: Medical Oncology, 2022, ISSN 1357-0560
Editore: Humana Press, Inc.
DOI: 10.1007/s12032-022-01740-w

Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation

Autori: Christopher Carroll, Auraya Manaprasertsak, Arthur Boffelli Castro, Hilda van den Bos, Diana C.J. Spierings, René Wardenaar, Anuraag Bukkuri, Niklas Engström, Etienne Baratchart, Minjun Yang, Andrea Biloglav, Charlie K. Cornwallis, Bertil Johansson, Catharina Hagerling, Marie Arsenian-Henriksson, Kajsa Paulsson, Sarah R. Amend, Sofie Mohlin, Floris Foijer, Alan McIntyre, Kenneth J. Pienta, Emma
Pubblicato in: Cancer Research Communications, Numero 4, 2024, Pagina/e 691-705, ISSN 2767-9764
Editore: American Association for Cancer Research (AACR)
DOI: 10.1158/2767-9764.crc-23-0396

Sulfidic anoxia in the oceans during the Late Ordovician mass extinctions – insights from molybdenum and uranium isotopic global redox proxies

Autori: Tais W.Dahl, Emma U.Hammarlund, Christian Mac Ørum Rasmussen, David P.G.Bond, Donald E.Canfield
Pubblicato in: Earth-Science Reviews, 2021, ISSN 0012-8252
Editore: Elsevier BV
DOI: 10.1016/j.earscirev.2021.103748

The sedimentary geochemistry and paleoenvironments project

Autori: Úna C Farrell, Rifaat Samawi, Savitha Anjanappa, Roman Klykov, Oyeleye O Adeboye, Heda Agic, Anne‐Sofie C Ahm, Thomas H Boag, Fred Bowyer, Jochen J Brocks, Tessa N Brunoir, Donald E Canfield, Xiaoyan Chen, Meng Cheng, Matthew O Clarkson, Devon B Cole, David R Cordie, Peter W Crockford, Huan Cui, Tais W Dahl, Lucas D Mouro, Keith Dewing, Stephen Q Dornbos, Nadja Drabon, Julie A Dumoulin, Joseph
Pubblicato in: Geobiology, 2021, ISSN 1472-4669
Editore: Wiley-Blackwell
DOI: 10.1111/gbi.12462

Early Silurian δ13Corg excursions in the foreland basin of Baltica, both familiar and surprising

Autori: Emma U. Hammarlund, David K. Loydell, Arne T. Nielsen, Niels H. Schovsbo
Pubblicato in: Palaeogeography, Palaeoclimatology, Palaeoecology, Numero 526, 2023, Pagina/e 126-135, ISSN 0031-0182
Editore: Elsevier BV
DOI: 10.1016/j.palaeo.2019.03.035

Hypoxia inducible factor‐2α importance for migration, proliferation, and self‐renewal of trunk neural crest cells

Autori: Camilla U. Niklasson, Elina Fredlund, Emanuela Monni, Jessica M. Lindvall, Zaal Kokaia, Emma U. Hammarlund, Marianne E. Bronner, Sofie Mohlin
Pubblicato in: Developmental Dynamics, 2021, ISSN 1058-8388
Editore: John Wiley & Sons Inc.
DOI: 10.1002/dvdy.253

Benthic diel oxygen variability and stress as potential drivers for animal diversification in the Neoproterozoic-Palaeozoic

Autori: Emma U. Hammarlund, Anuraag Bukkuri, Magnus D. Norling, Mazharul Islam, Nicole R. Posth, Etienne Baratchart, Christopher Carroll, Sarah R. Amend, Robert A. Gatenby, Kenneth J. Pienta, Joel S. Brown, Shanan E. Peters, Kasper Hancke
Pubblicato in: Nature Communications, Numero 16, 2025, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-025-57345-0

Tackling ongoing crises with collective evolutionary knowledge

Autori: Emma U. Hammarlund, Liselotte Jauffred, Nicole R. Posth, Karina K. Sand
Pubblicato in: Evolving Earth, Numero 2, 2024, Pagina/e 100043, ISSN 2950-1172
Editore: Elsevier BV
DOI: 10.1016/j.eve.2024.100043

Oxygen-sensing mechanisms across eukaryotic kingdoms and their roles in complex multicellularity

Autori: Emma U. Hammarlund, Emily Flashman, Sofie Mohlin, Francesco Licausi
Pubblicato in: Science, 2020, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.aba3512

On the Origin of Information Dynamics in Early Life

Autori: Robert A. Gatenby, Jill Gallaher, Hemachander Subramanian, Emma U. Hammarlund, Christopher J. Whelan
Pubblicato in: Life, Numero 15, 2025, Pagina/e 234, ISSN 2075-1729
Editore: MDPI AG
DOI: 10.3390/life15020234

Hypoxia Generated by Avian Embryo Growth Induces the HIF-α Response and Critical Vascularization

Autori: Christopher Carroll, Niklas Engström, Patrik F. Nilsson, Emma R. Haxen, Sofie Mohlin, Peter Berg, Ronnie N. Glud and Emma U. Hammarlund
Pubblicato in: Frontiers in Ecology and Evolution, 2021, ISSN 2296-701X
Editore: Frontiers in Ecology and Evolution
DOI: 10.3389/fevo.2021.675800

Roadmap to the study of gene and protein phylogeny and evolution—A practical guide

Autori: Florian Jacques, Paulina Bolivar, Kristian Pietras, Emma U Hammarlund
Pubblicato in: Plos One, 2023, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0279597

The contribution of evolvability to the <scp>eco‐evolutionary</scp> dynamics of competing species

Autori: Anuraag Bukkuri, Kenneth J. Pienta, Sarah R. Amend, Robert H. Austin, Emma U. Hammarlund, Joel S. Brown
Pubblicato in: Ecology and Evolution, Numero 13, 2023, ISSN 2045-7758
Editore: John Wiley and Sons Ltd
DOI: 10.1002/ece3.10591

Development of Iron Speciation Reference Materials for Palaeoredox Analysis

Autori: Lewis J. Alcott, Alexander J. Krause, Emma U. Hammarlund, Christian J. Bjerrum, Florian Scholz, Yijun Xiong, Andrew J. Hobson, Lesley Neve, Benjamin J. W. Mills, Christian März, Bernhard Schnetger, Andrey Bekker, Simon W. Poulton
Pubblicato in: Geostandards and Geoanalytical Research, Numero 44, 2023, Pagina/e 581-591, ISSN 1639-4488
Editore: Association Scientifique pour la Geologie et ses Applications
DOI: 10.1111/ggr.12342

Redox dynamics of later Cambrian oceans

Autori: Benjamin C. Gill, Tais W. Dahl, Emma U. Hammarlund, Matthew A. LeRoy, Gwyneth W. Gordon, Donald E. Canfield, Ariel D. Anbar, Timothy W. Lyons
Pubblicato in: Palaeogeography, Palaeoclimatology, Palaeoecology, 2021, ISSN 0031-0182
Editore: Elsevier BV
DOI: 10.1016/j.palaeo.2021.110623

A life history model of the ecological and evolutionary dynamics of polyaneuploid cancer cells

Autori: Anuraag Bukkuri, Kenneth J. Pienta, Robert H. Austin, Emma U. Hammarlund, Sarah R. Amend & Joel S. Brown
Pubblicato in: Scientific Reports, 2022, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-022-18137-4