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From hydrocarbons to original chiral building blocks: new solutions for sustainable & asymmetric CH functionalization of alkanes

Project description

Sustainable routes for the conversion of simple hydrocarbons into the original chiral building

Green chemistry focuses on the design of processes for the synthesis of organic molecules of interest while reducing waste generation and demand on rare and poorly available resources. The EU-funded AlCHiMIE project will work on complementary approaches for converting hydrocarbons – the simplest feedstock – into high value-added chiral alkanes that could become original building blocks for medicinal and agro-chemistry. The first approach will involve the metal-free functionalisation of hydrocarbons through regio- and stereoselective C–H bond activation. The second approach will concern the valorisation of alkanes through earth-abundant metal-catalysed C(sp3)–H activation. To achieve this goal and overcome the critical issue of the low reactivity of C(sp3)-H bonds, original catalytic systems involving the design of 'smart' ligands or the use of highly activated coupling partners will be proposed.

Call for proposal

ERC-2020-STG
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Host institution

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Address
Rue Michel -Ange 3
75794 Paris
France
Activity type
Research Organisations
EU contribution
€ 1 499 800

Beneficiaries (1)

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
France
EU contribution
€ 1 499 800
Address
Rue Michel -Ange 3
75794 Paris
Activity type
Research Organisations