Sustainable routes for the conversion of simple hydrocarbons into the original chiral building
Green chemistry focuses on the design of processes for the synthesis of organic molecules of interest while reducing waste generation and demand on rare and poorly available resources. The EU-funded AlCHiMIE project will work on complementary approaches for converting hydrocarbons – the simplest feedstock – into high value-added chiral alkanes that could become original building blocks for medicinal and agro-chemistry. The first approach will involve the metal-free functionalisation of hydrocarbons through regio- and stereoselective C–H bond activation. The second approach will concern the valorisation of alkanes through earth-abundant metal-catalysed C(sp3)–H activation. To achieve this goal and overcome the critical issue of the low reactivity of C(sp3)-H bonds, original catalytic systems involving the design of 'smart' ligands or the use of highly activated coupling partners will be proposed.
Fields of science
Call for proposal
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