Theranostic Immune Cell

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Supramolecular Heterodimer Peptides Assembly for Nanoparticles Functionalization

Autores: Clélia Mathieu, Shayamita Ghosh, Julien Draussin, Adeline Gasser, Guillaume Jacquot, Mainak Banerjee, Tanushree Gupta, Marc Schmutz, Céline Mirjolet, Olivier Tillement, François Lux, Andrey S. Klymchenko, Mariel Donzeau, Xavier Pivot, Sébastien Harlepp, Alexandre Detappe
Publicado en: Advanced Healthcare Materials, 2024, ISSN 2192-2659
Editor: World Scientific
DOI: 10.1002/adhm.202304250

Landscape of Subcutaneous Administration Strategies for Monoclonal Antibodies in Oncology

Autores: Guillaume Jacquot, Pedro Lopez Navarro, Coralie Grange, Lotfi Boudali, Sébastien Harlepp, Xavier Pivot, Alexandre Detappe
Publicado en: Advanced Materials, Edición 36, 2025, ISSN 0935-9648
Editor: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202406604

Engineering the subcutaneous delivery of antibody-drug conjugates

Autores: Alexandre Detappe, María Gutiérrez-Blanco, Xavier Pivot
Publicado en: Journal of Controlled Release, Edición 395, 2026, Página(s) 114941, ISSN 0168-3659
Editor: Elsevier BV
DOI: 10.1016/j.jconrel.2026.114941

Spacer engineering in nanoparticle–peptide conjugates boosts targeting specificity for tumor-associated antigens

Autores: María de los Angeles Ramírez, Jolie Bou-Gharios, Barbara Freis, Julien Draussin, Clémence Cheignon, Loic J. Charbonnière, Sophie Laurent, Thomas Gevart, Adeline Gasser, Sebastian Jung, Fabien Rossetti, Olivier Tillement, Georges Noel, Xavier Pivot, Alexandre Detappe, Sylvie Bégin-Colin, Sébastien Harlepp
Publicado en: Nanoscale, Edición 17, 2026, Página(s) 5021-5032, ISSN 2040-3364
Editor: Royal Society of Chemistry
DOI: 10.1039/d4nr02931c

Optimal Physicochemical Properties of Antibody–Nanoparticle Conjugates for Improved Tumor Targeting

Autores: Vincent Mittelheisser, Pierre Coliat, Eric Moeglin, Lilian Goepp, Jacky G. Goetz, Loic J. Charbonnière, Xavier Pivot, Alexandre Detappe
Publicado en: Advanced Materials, 2022, ISSN 1521-4095
Editor: Wiley
DOI: 10.1002/adma.202110305

Clinically Translatable Transcrocetin Delivery Platform for Correction of Tumor Hypoxia and Enhancement of Radiation Therapy Effects

Autores: Marie-Charlotte Diringer, Pierre Coliat, Clélia Mathieu, Nina Laurent, Carole Mura, Mainak Banerjee, Chen Zhu, Anna Grabowska, Alison Ritchie, Philip Clarke, Alexandre Bernard, Claire Vit, Hélène Burckel, Georges Noel, Peter Harvey, Xavier Pivot, Alexandre Detappe
Publicado en: Small, 2023, ISSN 1613-6810
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202205961

Subcutaneous Administration of a Zwitterionic Chitosan‐Based Hydrogel for Controlled Spatiotemporal Release of Monoclonal Antibodies

Autores: Thomas Gréa, Guillaume Jacquot, Arthur Durand, Clélia Mathieu, Adeline Gasser, Chen Zhu, Mainak Banerjee, Elyse Hucteau, Joris Mallard, Pedro Lopez Navarro, Bogdan V. Popescu, Eloise Thomas, David Kryza, Jacqueline Sidi‐Boumedine, Giuseppe Ferrauto, Eliana Gianolio, Guillaume Fleith, Jérôme Combet, Susana Brun, Stéphane Erb, Sarah Cianferani, Loïc J. Charbonnière, Lyne Fellmann, Céline M
Publicado en: Advanced Materials, Edición 36, 2025, ISSN 0935-9648
Editor: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202308738

Nanomaterials Trigger Functional Anti‐Tumoral Responses in Primary Human Immune Cells

Autores: Vincent Mittelheisser, Olivier Lefebvre, Mainak Banerjee, Shayamita Ghosh, Amandine Dupas, Marie‐Charlotte Diringer, Juliette Blumberger, Louis Bochler, Sébastien Harlepp, Annabel Larnicol, Angélique Pichot, Tristan Stemmelen, Anne Molitor, Chloé Moritz, Christine Carapito, Raphaël Carapito, Loïc J. Charbonnière, François Lux, Olivier Tillement, Jacky G. Goetz, Alexandre Detappe
Publicado en: Advanced Science, Edición 12, 2026, ISSN 2198-3844
Editor: Wiley
DOI: 10.1002/advs.202505729

Subcutaneous Administration of a Zwitterionic Chitosan‐Based Hydrogel for Controlled Spatiotemporal Release of Monoclonal Antibodies

Autores: Thomas Gréa; Guillaume Jacquot; Arthur Durand; Clélia Mathieu; Adeline Gasser; Chen Zhu; Mainak Banerjee; Elyse Hucteau; Joris Mallard; Pedro Lopez Navarro; Bogdan V. Popescu; Eloise Thomas; David Kryza; Jacqueline Sidi‐Boumedine; Giuseppe Ferrauto; Eliana Gianolio; Guillaume Fleith; Jérôme Combet; Susana Brun; Stéphane Erb; Sarah Cianferani; Loïc J. Charbonnière; Lyne Fellmann; Céline M
Publicado en: Advanced Materials, 2024, ISSN 0935-9648
Editor: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202308738

A Modular Supramolecular Peptide Platform Reveals Atomic-Number-Dependent Mechanisms Driving Radioenhancement

Autores: Sebastian Jung, Pedro Lopez Navarro, Elsa Barbé, Adeline Gasser, Jolie Bou-Gharios, Mariel Donzeau, Céline Mirjolet, Georges Noel, Jean-Louis Schmitt, Xavier Pivot, Sébastien Harlepp, Alexandre Detappe
Publicado en: ACS Nano, Edición 19, 2025, Página(s) 40394-40403, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.5c09326

Functionalization of chitosan with a polycarboxylic macrocycle yields injectable hydrogel with pH and salts responsiveness

Autores: Arthur Durand, Thomas Gréa, Gabin Lebeau, Guillaume Jacquot, Augustin Tillement, Axel Aigle, Eloïse Thomas, David Kryza, Jacqueline Taleb, Giuseppe Ferrauto, Eliana Gianolio, Alain Géloën, Alexandra Montembault, Maria Gutiérrez-Blanco, Xavier Pivot, Sébastien Harlepp, Alexandre Detappe, Laurent David, François Lux, Olivier Tillement
Publicado en: Materials Today Advances, Edición 25, 2025, Página(s) 100565, ISSN 2590-0498
Editor: Elsevier BV
DOI: 10.1016/j.mtadv.2025.100565

From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates

Autores: Xavier Pivot, Sebastian Jung, Sébastien Harlepp, Alexandre Detappe
Publicado en: Advanced Materials, Edición 38, 2026, ISSN 0935-9648
Editor: United Nations Industrial Developement Organization
DOI: 10.1002/adma.74387

Anti-BCMA Immuno-nanoPET Radiotracers for Improved Detection of Multiple Myeloma

Autores: Eloise Thomas; Clélia Mathieu; Patricia Moreno-Gaona; Vincent Mittelheisser; François Lux; François Lux; Olivier Tillement; Xavier Pivot; P. Peter Ghoroghchian; P. Peter Ghoroghchian; Alexandre Detappe
Publicado en: Advanced Healthcare Materials, 2021, ISSN 2192-2640
Editor: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202101565

Dynamic precision cancer nanomedicine

Autores: Alexandre Detappe, Fabrice André
Publicado en: Nature Reviews Bioengineering, Edición 4, 2026, Página(s) 9-10, ISSN 2731-6092
Editor: Springer Science and Business Media LLC
DOI: 10.1038/s44222-025-00392-5

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