Understanding collective mechanisms of cell fate regulation using single-cell genomics

Project Information

AHH-OMICS

Grant agreement ID: 950349

DOI

10.3030/950349

EC signature date 13 November 2020

Start date 1 January 2021

End date 31 December 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 489 500,00

EU contribution

€ 1 489 500,00

Coordinated by

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

Spatiotemporal Patterns of Active Epigenetic Turnover

Author(s): Fabrizio Olmeda, Misha Gupta, Onurcan Bektas, Steffen Rulands
Published in: PRX Life, Issue 4, 2026, ISSN 2835-8279
Publisher: American Physical Society (APS)
DOI: 10.1103/89bj-79g5

Clonal dynamics of surface-driven growing tissues

Author(s): Ruslan I. Mukhamadiarov, Matteo Ciarchi, Fabrizio Olmeda, Steffen Rulands
Published in: Physical Review E, Issue 109, 2024, ISSN 2470-0045
Publisher: American Physical Society (APS)
DOI: 10.1103/physreve.109.064407

Scaling and self-similarity in the formation of the embryonic epigenome

Author(s): Fabrizio Olmeda, Tim Lohoff, Ioannis Kafetzopoulos, Stephen J. Clark, Laura Benson, Fatima Santos, Felix Krueger, Simon Walker, Wolf Reik, Steffen Rulands
Published in: Nature Physics, 2026, ISSN 1745-2473
Publisher: Nature Publishing Group
DOI: 10.1038/s41567-026-03263-x

Transcriptional landscapes underlying Notch-induced lineage conversion and plasticity of mammary basal cells

Author(s): Candice Merle, Calvin Rodrigues, Atefeh Pourkhalili Langeroudi, Robin Journot, Fabian Rost, Yiteng Dang, Steffen Rulands, Silvia Fre
Published in: The EMBO Journal, Issue 44, 2025, Page(s) 2827-2855, ISSN 1460-2075
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s44318-025-00424-1

Field theory of enzyme-substrate systems with restricted long-range interactions

Author(s): Fabrizio Olmeda, Steffen Rulands
Published in: Physical Review E, Issue 110(2), 2024, Page(s) 024404, ISSN 2470-0045
Publisher: American Physical Society
DOI: 10.1103/physreve.110.024404

FOXO1-mediated lipid metabolism maintains mammalian embryos in dormancy

Author(s): Vera A. van der Weijden, Maximilian Stötzel, Dhanur P. Iyer, Beatrix Fauler, Elzbieta Gralinska, Mohammed Shahraz, David Meierhofer, Martin Vingron, Steffen Rulands, Theodore Alexandrov, Thorsten Mielke, Aydan Bulut-Karslioglu
Published in: Nature Cell Biology, Issue 26, 2026, Page(s) 181-193, ISSN 1465-7392
Publisher: Nature Publishing Group
DOI: 10.1038/s41556-023-01325-3

Self-organization of plasticity and specialization in a primitively social insect.

Author(s): Solenn Patalano; Adolfo Alsina; Carlos Gregorio-Rodríguez; Martin Bachman; Stephanie Dreier; Irene Hernando-Herraez; Paulin Nana; Shankar Balasubramanian; Seirian Sumner; Wolf Reik; Steffen Rulands
Published in: Cell Systems, Issue 13(9), 2022, Page(s) 768-779.e4, ISSN 2405-4720
Publisher: Cell Press
DOI: 10.1016/j.cels.2022.08.002

scEpiAge: an age predictor highlighting single-cell ageing heterogeneity in mouse blood

Author(s): Marc Jan Bonder, Stephen J. Clark, Felix Krueger, Siyuan Luo, João Agostinho de Sousa, Aida M. Hashtroud, Thomas M. Stubbs, Anne-Katrien Stark, Steffen Rulands, Oliver Stegle, Wolf Reik & Ferdinand von Meyenn
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-51833-5

Controlling noise with self-organized resetting

Author(s): Felix J. Meigel, Steffen Rulands
Published in: Communications Physics, Issue 8, 2025, ISSN 2399-3650
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s42005-025-01985-7