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Peripheral Nervous System Tissue Engineering for Medical and Cosmetic Testing Applications

Project description

3D human tissue models for medical and cosmetic screenings

The goal of the EU-funded PLATFORMA project is to produce novel high-content platforms for the commercial screening of cosmetics, pollutants and new therapeutics. Partners aim to build two 3D modular human tissues supported by laser-printed biocompatible scaffolds for the electrophysiological monitoring of cell conditions. The skin-sensory module will be a world-first innervated human skin tissue model to enable the study and testing of peripheral nervous system responses to external stimuli in a physiologically relevant context. The muscle-motor module will be a motor neuroskeletal muscle tissue model to allow non-invasive recordings of neuromuscular transmission in real time. It will support studies on muscular atrophies and motor neuron diseases with genetically engineered or patient-derived cells and the analysis of drug effects.

Call for proposal

H2020-EIC-FETPROACT-2019
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Funding Scheme

RIA - Research and Innovation action

Coordinator

ASTON UNIVERSITY
Address
Aston Triangle
B4 7ET Birmingham
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 360 650

Participants (5)

GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER
Germany
EU contribution
€ 391 875
Address
Welfengarten 1
30167 Hannover
Activity type
Higher or Secondary Education Establishments
AXOL BIOSCIENCE LTD
United Kingdom
EU contribution
€ 374 375
Address
Suite 3 The Science Village Chesterford Research P
CB10 1XL Cambridge
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
LASER NANOFAB GMBH
Germany
EU contribution
€ 419 050
Address
Steinwartskamp 65
30826 Garbsen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
STRATICELL SCREENING TECHNOLOGIES SA
Belgium
EU contribution
€ 375 000
Address
Rue Jean Sonet 10 Parc Scientifique Crealys Cri Andromede
5032 Gembloux Les Isnes
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
DLM CONSULTANCY SERVICES LTD
United Kingdom
EU contribution
€ 79 043,75
Address
3M Buckley Innovation Centre
HD1 3BD Huddersfield
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)