Peripheral Nervous System Tissue Engineering for Medical and Cosmetic Testing Applications

Project description

3D human tissue models for medical and cosmetic screenings

The goal of the EU-funded PLATFORMA project is to produce novel high-content platforms for the commercial screening of cosmetics, pollutants and new therapeutics. Partners aim to build two 3D modular human tissues supported by laser-printed biocompatible scaffolds for the electrophysiological monitoring of cell conditions. The skin-sensory module will be a world-first innervated human skin tissue model to enable the study and testing of peripheral nervous system responses to external stimuli in a physiologically relevant context. The muscle-motor module will be a motor neuroskeletal muscle tissue model to allow non-invasive recordings of neuromuscular transmission in real time. It will support studies on muscular atrophies and motor neuron diseases with genetically engineered or patient-derived cells and the analysis of drug effects.

Fields of science

• medical and health sciences › medical biotechnology › tissue engineering
• natural sciences › biological sciences › neurobiology

Programme(s)

• H2020-EU.1.2.2. - FET Proactive

Topic(s)

• FETPROACT-EIC-06-2019 - EIC Transition to Innovation Activities

Call for proposal

H2020-EIC-FETPROACT-2019
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

ASTON UNIVERSITY

Address

Aston Triangle
B4 7ET Birmingham
United Kingdom

Activity type

Higher or Secondary Education Establishments

EU contribution

€ 360 650

Participants (5)

GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER

Germany

EU contribution

€ 391 875

Address

Welfengarten 1
30167 Hannover

Activity type

Higher or Secondary Education Establishments

AXOL BIOSCIENCE LTD

United Kingdom

EU contribution

€ 374 375

Address

Suite 3 The Science Village Chesterford Research P
CB10 1XL Cambridge

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

LASER NANOFAB GMBH

Germany

EU contribution

€ 419 050

Address

Steinwartskamp 65
30826 Garbsen

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

STRATICELL SCREENING TECHNOLOGIES SA

Belgium

EU contribution

€ 375 000

Address

Rue Jean Sonet 10 Parc Scientifique Crealys Cri Andromede
5032 Gembloux Les Isnes

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

DLM CONSULTANCY SERVICES LTD

United Kingdom

EU contribution

€ 79 043,75

Address

3M Buckley Innovation Centre
HD1 3BD Huddersfield

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)