3D human tissue models for medical and cosmetic screenings
The goal of the EU-funded PLATFORMA project is to produce novel high-content platforms for the commercial screening of cosmetics, pollutants and new therapeutics. Partners aim to build two 3D modular human tissues supported by laser-printed biocompatible scaffolds for the electrophysiological monitoring of cell conditions. The skin-sensory module will be a world-first innervated human skin tissue model to enable the study and testing of peripheral nervous system responses to external stimuli in a physiologically relevant context. The muscle-motor module will be a motor neuroskeletal muscle tissue model to allow non-invasive recordings of neuromuscular transmission in real time. It will support studies on muscular atrophies and motor neuron diseases with genetically engineered or patient-derived cells and the analysis of drug effects.
Fields of science
Call for proposal
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Funding SchemeRIA - Research and Innovation action
CB10 1XL Cambridge
HD1 3BD Huddersfield