Enhancing and Strengthening the Excellence in Interdisciplinary Biomedical Research at TRANSCEND

Informazioni relative al progetto

ESEI-BioMed

ID dell’accordo di sovvenzione: 952390

DOI

10.3030/952390

Data della firma CE 10 Giugno 2020

Data di avvio 1 Gennaio 2021

Data di completamento 31 Dicembre 2026

Finanziato da

• Establishing ‚ERA Chairs’

Costo totale

€ 2 500 000,00

Contributo UE

€ 2 500 000,00

Coordinato da

INSTITUTUL REGIONAL DE ONCOLOGIE IASI
Romania

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (12)

Equipment upgrading 2

A report on the acquisition of the new equipment and the related training will be produced and delivered to the EC in accordance with the time planning (M24). Since a key equipment is mandatory to be acquired as soon as possible, as explained in the Methodology, a report on the equipment upgrading will be also provided at M12.

Website of the project

website of the ESEI-BioMed project will be launched M1. A report on the website creation will be provided to the EC in parallel with the reports planned for M24.

Organization of events 1

A report describing the organization of events at national level necessary to communicate and promote the project to broad audience will be produced and provided to the EC for each reporting period (M24, M56 and M72).

Scientific outputs 1

A report describing the scientific progress, achievements and results of the project will be produced and delivered to the EC in accordance with the time plan (M40, M56 and M72).

Organization of meetings 1

A report describing the organization of events at national level necessary to establish national collaborations will be produced and provided to the EC for each reporting period (M24, M56 and M72).

Articles and patents 1

A report on all manuscript submitted, articles published and patent applications will be produced and provided to the EC for each reporting period (M40, M56, M72). At least 10 publications (open access included) in peer-reviewed journals and 2 patent applications are foreseen for this project.

Visits in the European laboratories 1

A report describing the the visits made in the European laboratories by the team members will be produced and published on the website of the project. It will also be provided to the EC for each reporting period (M40, M56 and M72).

Promotion materials 1

A report describing all the promotion materials elaborated during the project run will be produced and provided to the EC for each reporting period M12 M40 and M72

Promotion materials 2

A report describing all the promotion materials elaborated during the project run will be produced and provided to the EC for each reporting period (M12, M40 and M72).

Dissemination, communication and promotion (DCP) plan 1

A reporting describing the strategy and means by which the ESEI-BioMed will reach the entire community will be produced and reported to the EC in accordance with the time plan (M24, M56). The plan will be also discussed with IAB members.

Equipment upgrading 1

A report on the acquisition of the new equipment and the related training will be produced and delivered to the EC in accordance with the time planning M24 Since a key equipment is mandatory to be acquired as soon as possible as explained in the Methodology a report on the equipment upgrading will be also provided at M12

Participation in scientific meetings 1

A report describing the participation in at national and international scientific meetings will be produced and published on the website of the project. It will also be provided to the EC for each reporting period (M24, M56 and M72).

Pubblicazioni

Peer reviewed articles (18)

LDH-chitosan bionanocomposites for oncologic applications: A refreshing perspective on the mutual influence through intermolecular forces toward controlled morphology and dispersion

Autori: Dragos-Ioan Olariu, Vera Maria Platon, Alina Ibanescu, Maria Daniela Vlad, Camelia Mihaela Zara-Danceanu, Doina Lutic, Luminita Marin, Brindusa Dragoi
Pubblicato in: International Journal of Biological Macromolecules, Numero 329, 2026, Pagina/e 147495, ISSN 0141-8130
Editore: Elsevier BV
DOI: 10.1016/j.ijbiomac.2025.147495

Liposomal-Based Formulations: A Path from Basic Research to Temozolomide Delivery Inside Glioblastoma Tissue

Autori: Roxana-Maria Amarandi; Alina Ibanescu; Eugen Carasevici; Luminita Marin; Brindusa Dragoi
Pubblicato in: Pharmaceutics, Numero 1, 2022, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14020308

Synthesis of ZnO/Au Nanocomposite for Antibacterial Applications

Autori: Violeta Dediu, Mariana Busila, Vasilica Tucureanu, Florentina Ionela Bucur, Florina Silvia Iliescu, Oana Brincoveanu, Ciprian Iliescu
Pubblicato in: Nanomaterials, Numero 12, 2024, Pagina/e 3832, ISSN 2079-4991
Editore: MDPI
DOI: 10.3390/nano12213832

Co-Encapsulation of Multiple Antineoplastic Agents in Liposomes by Exploring Microfluidics

Autori: Sajid Asghar, Radu Iliescu, Rares-Ionut Stiufiuc, Brindusa Dragoi
Pubblicato in: International Journal of Molecular Sciences, Numero 26, 2025, Pagina/e 3820, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms26083820

NHF-derived carbon dots: prevalidation approach in breast cancer treatment

Autori: Crina Elena Tiron, Gabriel Luta, Mihail Butura, Florin Zugun-Eloae, Corneliu S. Stan, Adina Coroaba, Elena-Laura Ursu, Gabriela Dumitrita Stanciu, Adrian Tiron
Pubblicato in: Scientific Reports, Numero 10/1, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-020-69670-z

Mn-based 2D layered nanomaterials for boosting the MRI signal

Autori: Brindusa Dragoi, Cristina Mariana Uritu, Laurentiu Agrigoroaie, Doina Lutic, Thomas Cacciaguerra, Vasile Hulea, Eugen Carasevici
Pubblicato in: Materials Letters, Numero 288, 2021, Pagina/e 129331, ISSN 0167-577X
Editore: Elsevier BV
DOI: 10.1016/j.matlet.2021.129331

Multi spectroscopic investigation of maisine-based microemulsions as convenient carriers for co-delivery of anticancer and anti-inflammatory drugs

Autori: Mirela Nistor, Alina Nicolescu, Roxana-Maria Amarandi, Aurel Pui, Rares-Ionut Stiufiuc, Brindusa Dragoi
Pubblicato in: Scientific Reports, Numero 15, 2025, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-025-89540-w

A Coarse-Grained Molecular Dynamics Perspective on the Release of 5-Fluorouracil from Liposomes

Autori: Roxana-Maria Amărandi, Luminiţa Marin, Brînduşa Drăgoi, Andrei Neamţu
Pubblicato in: Molecular Pharmaceutics, Numero 21, 2024, Pagina/e 6137-6152, ISSN 1543-8384
Editore: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.4c00328

Erythromycin Formulations—A Journey to Advanced Drug Delivery

Autori: Vera-Maria Platon, Brindusa Dragoi, Luminita Marin
Pubblicato in: Pharmaceutics, Numero 14, 2024, Pagina/e 2180, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14102180

Impact of Lipid Composition on Vesicle Protein Adsorption: A BSA Case Study

Autori: Roxana-Maria Amărandi, Andrei Neamṭu, Rareş-Ionuṭ Ştiufiuc, Luminiṭa Marin, Brînduşa Drăgoi
Pubblicato in: ACS Omega, Numero 9, 2024, Pagina/e 17903-17918, ISSN 2470-1343
Editore: American Chemical Society
DOI: 10.1021/acsomega.3c09131

Design and Physicochemical Characterization of a Multifunctional Maisine-Based Microemulsion Incorporating Doxorubicin@Mn-Doped Magnetite Nanoparticles for MRI, Hyperthermia, and Drug Delivery

Autori: Mirela Nistor, Daniel Gherca, Cristina Mariana Uritu, Marian Grigoras, Vera Balan, Raluca M. Fratila, Rares-Ionut Stiufiuc, Brindusa Dragoi, Aurel Pui
Pubblicato in: Nanomaterials, Numero 16, 2026, Pagina/e 1065, ISSN 2079-4991
Editore: MDPI AG
DOI: 10.3390/nano16171065

Engineering the Morphostructural Properties and Drug Loading Degree of Organic–Inorganic Fluorouracil–MgAl LDH Nanohybrids by Rational Control of Hydrothermal Treatment

Autori: Alina Ibanescu, Dragos-Ioan Olariu, Doina Lutic, Vasile Hulea, Brindusa Dragoi
Pubblicato in: ACS Omega, Numero 8, 2023, Pagina/e 26102-26121, ISSN 2470-1343
Editore: American Chemical Society
DOI: 10.1021/acsomega.3c02288

Precise-engineering of monodisperse magnetite nanoparticles with low-level of cobalt doping for enhanced MRI contrast performance

Autori: Mirela Nistor, Vera Balan, Aurel Pui, Camelia Mihaela Zara-Danceanu, Paula Alexandra Postu, Marian Grigoras, Daniel Gherca, Valentin Toma, Cristina Mariana Uritu, Raluca M. Fratila, Rares-Ionut Stiufiuc, Brindusa Dragoi
Pubblicato in: Materials & Design, Numero 262, 2026, Pagina/e 115386, ISSN 0264-1275
Editore: Elsevier BV
DOI: 10.1016/j.matdes.2025.115386

Understanding DNA Epigenetics by Means of Raman/SERS Analysis for Cancer Detection

Autori: Luca David, Anca Onaciu, Valentin Toma, Rareș-Mario Borșa, Cristian Moldovan, Adrian-Bogdan Țigu, Diana Cenariu, Ioan Șimon, Gabriela-Fabiola Știufiuc, Eugen Carasevici, Brîndușa Drăgoi, Ciprian Tomuleasa, Rareș-Ionuț Știufiuc
Pubblicato in: Biosensors, Numero 14, 2024, Pagina/e 41, ISSN 2079-6374
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios14010041

Entrapment of N-Hydroxyphthalimide Carbon Dots in Different Topical Gel Formulations: New Composites with Anticancer Activity

Autori: Corina-Lenuta Savin, Crina Tiron, Eugen Carasevici, Corneliu S. Stan, Sorin Alexandru Ibanescu, Bogdan C. Simionescu, Catalina A. Peptu
Pubblicato in: Pharmaceutics, Numero 11/7, 2019, Pagina/e 303, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics11070303

Magnetic Nanoparticles: Synthesis, Characterization, and Their Use in Biomedical Field

Autori: Gabriela Fabiola Stiufiuc, Rares Ionut Stiufiuc
Pubblicato in: Applied Sciences, Numero 14, 2024, Pagina/e 1623, ISSN 2076-3417
Editore: MDPI
DOI: 10.3390/app14041623

MnAl-Layered Double Hydroxide Nanosheets Infused with Fluorouracil for Cancer Diagnosis and Therapy

Autori: Brindusa Dragoi, Cristina Mariana Uritu, Laurentiu Agrigoroaie, Doina Lutic, Vasile Hulea, Georgeta Postole, Adina Coroaba, Eugen Carasevici
Pubblicato in: ACS Applied Nano Materials, 2021, ISSN 2574-0970
Editore: American Chemical Society
DOI: 10.1021/acsanm.0c03365

Microfluidic trends in drug screening and drug delivery

Autori: Jianguo Feng, Jiri Neuzil, Andreas Manz, Ciprian Iliescu, Pavel Neuzil
Pubblicato in: TrAC Trends in Analytical Chemistry, Numero 158, 2023, Pagina/e 116821, ISSN 0165-9936
Editore: Elsevier BV
DOI: 10.1016/j.trac.2022.116821