From pathobioLogy to synoviA on chip: driving rheuMatoId arthritis to the precisioN medicine GOal

Informations projet

FLAMIN-GO

N° de convention de subvention: 953121

DOI

10.3030/953121

Date de signature de la CE 6 Novembre 2020

Date de début 1 Janvier 2021

Date de fin 31 Decembre 2025

Financé au titre de

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies

Coût total

Aucune donnée

Contribution de l’UE

€ 5 821 613,75

Coordonné par

UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO
Italy

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Websites, patent fillings, videos etc. (3)

Communication plan and dissemination plan

It will describe the project dissemination and communication strategies including the logo and graphical layout guidelines

Dissemination and communication package

It will contain all dissemination products prepared during the first reporting period RP1 1 all promotional materials developed and their distribution 2 snapshots describing the main sections of the project website 3 reference regarding all the social media used and any radio and TV broadcasts or press interviews 4 text of all the press releases published and the press conferences organized and related press review 5 the agenda of the attended events external to the project and the presentations given 6 the agenda presentations and customer satisfaction questionnaires regarding project events organized in P1 7 references to all publications produced in the reporting period 8 information on clustering activities

Dissemination and communication package - RP2

It will contain all dissemination products prepared during the second reporting period (RP2): 1) all promotional materials developed and their distribution; 2) snapshots describing the main sections of the project website; 3) reference regarding all the social media used, and any radio and TV broadcasts or press interviews; 4) text of all the press releases published and the press conferences organized and related press review; 5) the agenda of the attended events external to the project and the presentations given; 6) the agenda, presentations, and customer satisfaction questionnaires regarding project events organized in P1; 7) references to all publications produced in the reporting period; 8) information on clustering activities.

Publications

Peer reviewed articles (20)

Ph-Sensing Hydrogels for Non-Invasive Metabolism Monitoring in Tumor Spheroids

Auteurs: Riccardo Rizzo, Valentina Onesto, Giulia Morello, Helena Iuele, Francesca Scalera, Stefania Forciniti, Giuseppe Gigli, Alessandro Polini, Francesca Gervaso, Loretta L. del Mercato
Publié dans: Materials Today Bio, Numéro Volume 20, June 2023, 100655, 2023, ISSN 2590-0064
Éditeur: Elsevier
DOI: 10.2139/ssrn.4364505

VAT photopolymerization 3D printing optimization of high aspect ratio structures for additive manufacturing of chips towards biomedical applications

Auteurs: Alessio Bucciarelli, Xenia Paolelli, Eleonora De Vitis, Nora Selicato, Francesca Gervaso, Giuseppe Gigli, Lorenzo Moroni, Alessandro Polini
Publié dans: Additive Manufacturing, Numéro Volume 60, Part A, December 2022, 103200, 2022, ISSN 2214-8604
Éditeur: Elsevier BV
DOI: 10.1016/j.addma.2022.103200

Preparation and characterization of salt-mediated injectable thermosensitive chitosan/pectin hydrogels for cell embedding and culturing

Auteurs: Morello, Giulia; Polini, Alessandro; Scalera, Francesca; Rizzo, Riccardo; Gigli, Giuseppe; Gervaso, Francesca
Publié dans: Polymers, Numéro 13(16), 2021, Page(s) 2674, ISSN 2073-4360
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/polym13162674

Nano-Microparticle Platforms in Developing Next-Generation Vaccines

Auteurs: Giuseppe Cappellano; Hugo Abreu; Chiara Casale; Umberto Dianzani; Annalisa Chiocchetti
Publié dans: Vaccines, Numéro 9(6), 2021, Page(s) 606, ISSN 2076-393X
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines9060606

Nutrition and Rheumatoid Arthritis Onset: A Prospective Analysis Using the UK Biobank

Auteurs: Camilla Barbero Mazzucca; Lorenza Scotti; Giuseppe Cappellano; Francesco Barone-Adesi 3; Annalisa Chiocchetti
Publié dans: Nutrients, Numéro 14(8), 2022, Page(s) 1554, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu14081554

Fluorescent nano- and microparticles for sensing cellular microenvironment: past, present and future applications

Auteurs: Grasso, Giuliana, Colella Francesco, Forciniti Stefania, Onesto Valentina, Iuele Helena, Siciliano Anna Chiara, Carnevali Federica, Chandra Anil, Gigli Giuseppe, del Mercato Loretta L.
Publié dans: Nanoscale Advances, Numéro 5, 2023, Page(s) 4311-4336, ISSN 2516-0230
Éditeur: RSC Publishing
DOI: 10.1039/d3na00218g

Chitosan and Pectin Hydrogels for Tissue Engineering and In Vitro Modeling

Auteurs: Morello Giulia, De Iaco Gianvito, Gigli Giuseppe, Polini Alessandro, Gervaso Francesca
Publié dans: Gels, Numéro 9(2), 2023, Page(s) 132, ISSN 2310-2861
Éditeur: MDPI
DOI: 10.3390/gels9020132

Micropathological Chip Modeling the Neurovascular Unit Response to Inflammatory Bone Condition

Auteurs: Estrela Neto; Ana C Monteiro; Catarina L Pereira; Miguel Simões; João P Conde; Virginia Chu; Bruno Sarmento; Meriem Lamghari
Publié dans: Advanced Healthcare Materials, Numéro 11(11), 2022, Page(s) 2102305, ISSN 2192-2640
Éditeur: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202102305

Inducible T-Cell Costimulator Ligand Plays a Dual Role in Melanoma Metastasis upon Binding to Osteopontin or Inducible T-Cell Costimulator

Auteurs: Davide Raineri; Giuseppe Cappellano; Beatrice Vilardo; Federica Maione; Nausicaa Clemente; Elena Canciani; Elena Boggio; Casimiro Luca Gigliotti; Chiara Monge; Chiara Dianzani; Renzo Boldorini; Umberto Dianzani; Annalisa Chiocchetti
Publié dans: Biomedicines, Numéro 10(1), 2021, Page(s) 51, ISSN 2227-9059
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/biomedicines10010051

How to Tackle the Relationship between Autoimmune Diseases and Diet: Well Begun Is Half-Done

Auteurs: Camilla Barbero Mazzucca; Davide Raineri; Giuseppe Cappellano; Annalisa Chiocchetti
Publié dans: Nutrients, Numéro 13(11), 2021, Page(s) 3956, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu13113956

Viscoelastic properties of suspended cells measured with shear flow deformation cytometry

Auteurs: Gerum R., Mirzahossein E., Eroles M., Elsterer J., Mainka A., Bauer A., Sonntag S., Winterl A., Bartl J., Fischer L., Abuhattum S., Goswami R., Girardo S., Guck J., Schrüfer S., Ströhlein N., Nosratlo M., Herrmann H., Schultheis D., Rico F., Müller S. J., Gekle S., Fabry B.
Publié dans: Elife, Numéro 11, e78823, 2022, ISSN 2050-084X
Éditeur: eLife Sciences Publications
DOI: 10.7554/elife.78823

High levels of circulating osteopontin in inflammatory lung disease regardless of Sars-CoV-2 infection

Auteurs: Giuseppe Cappellano, Hugo Abreu, Davide Raineri, Lorenza Scotti, Luigi Castello, Rosanna Vaschetto, Annalisa Chiocchetti
Publié dans: EMBO Molecular Medicine, Numéro 13(5), 2021, Page(s) e14124, ISSN 1757-4684
Éditeur: EMBO Press
DOI: 10.15252/emmm.202114124

Worse Disease Prognosis Is Associated to an Increase of Platelet-Derived Extracellular Vesicles in Hospitalized SARS-CoV-2 Patients

Auteurs: Raineri Davide, Venegoni Chiara, Calella Maria Grazia, Vaschetto Rosanna, Scotti Lorenza, Manfredi Marcello, Gavello Francesco, Castello Luigi, Chiocchetti Annalisa, Cappellano Giuseppe
Publié dans: Disease Markers, Numéro Volume 2022, Article ID 8074655, 2022, ISSN 0278-0240
Éditeur: IOS Press
DOI: 10.1155/2022/8074655

Cell-Laden 3D Printed GelMA/HAp and THA Hydrogel Bioinks: Development of Osteochondral Tissue-like Bioinks

Auteurs: Jahangir S., Vecstaudza J., Augurio A., Canciani E., Stipniece L., Locs J., Alini M., Serra T.
Publié dans: Materials, Numéro 16(22), 2023, Page(s) 7214, ISSN 1996-1944
Éditeur: MDPI Open Access Publishing
DOI: 10.3390/ma16227214

Extracellular Vesicles in Musculoskeletal Regeneration: Modulating the Therapy of the Future

Auteurs: Abreu, Hugo; Canciani, Elena; Raineri, Davide; Cappellano, Giuseppe; Rimondini, Lia; Chiocchetti, Annalisa
Publié dans: Cells, Numéro 11(1), 2021, Page(s) 43, ISSN 2073-4409
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cells11010043

Image-based cell sorting using focused travelling surface acoustic waves

Auteurs: Ahmad Ahsan Nawaz, Despina Soteriou, Catherine K. Xu, Ruchi Goswami, Maik Herbig, Jochen Guck and Salvatore Girardo
Publié dans: Lab on Chip, Numéro Numéro 2, 2023, 2023, Page(s) 372-387, ISSN 1473-0189
Éditeur: RSC Publishing
DOI: 10.1039/d2lc00636g

The convergence of high-tech emerging technologies into the next stage of organ-on-a-chips

Auteurs: Polini, Alessandro; Moroni, Lorenzo
Publié dans: Biomaterials and Biosystems, Numéro 1, 2021, Page(s) 100012, ISSN 2666-5344
Éditeur: Elsevier BV
DOI: 10.1016/j.bbiosy.2021.100012

Efficient and gentle delivery of molecules into cells with different elasticity via Progressive Mechanoporation

Auteurs: Alena Uvizl; Ruchi Goswami; Shanil Gandhi; Martina Augsburg; Frank Buchholz; Jochen Guck; Jörg Mansfeld; Salvatore Girardo
Publié dans: Lab on a Chip, Numéro 21, 2021, Page(s) 2437-2452, ISSN 1473-0197
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d0lc01224f

Thermosensitive chitosan-based hydrogels supporting motor neuron-like NSC-34 cell differentiation

Auteurs: Stanzione, Antonella; Polini, Alessandro; La Pesa, Velia; Quattrini, Angelo; Gigli, Giuseppe; Moroni, Lorenzo; Gervaso, Francesca
Publié dans: Biomaterials Science, Numéro 9, 2021, Page(s) 7492-7503, ISSN 2047-4830
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d1bm01129d

A microfabricated multi‑compartment device for neuron and Schwann cell differentiation

Auteurs: De Vitis, Eleonora; La Pesa, Velia; Gervaso, Francesca; Romano, Alessandro; Quattrini, Angelo; Gigli, Giuseppe; Moroni, Lorenzo; Polini, Alessandro
Publié dans: Scientific reports, Numéro 11, 2021, Page(s) 7019, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-021-86300-4

Conference proceedings (2)

Development of bioprinted osteochondral tissue: an in-vitro model for drug discovery

Auteurs: Jahangir Shahrbanoo; Vecstaudža Jana; Canciani Elena; Ločs Jānis; Alini Mauro; Serra Tiziano
Publié dans: TERMIS 2022 Conference Book and Book Abstracts, 2023, Page(s) 191-192, ISSN 1937-3341
Éditeur: Mary Ann Liebert, Inc., publishers
DOI: 10.5281/zenodo.6587068

Amorphous calcium phosphate nanoparticles for development of 3D printing bio-inks for orthopaedic application

Auteurs: Vecstaudza, Jana; Locs, Janis
Publié dans: eCM Periodical, Numéro 3, 2021, Page(s) 20, ISSN 2522-235X
Éditeur: AO Research Institute Davos
DOI: 10.5281/zenodo.6586447