Project description DEENESFRITPL A one-stop shop for the engineering and 3D printing of biocompatible tissue scaffolds Tissue engineering and tissue regeneration are strongly interrelated topics of research, and both have come a long way. Much as teaching a person to fish is preferable to giving them a fish, an implant that encourages regeneration and a life beyond itself is key to the sustainability and long-term impact of the engineered tissue. The EU-funded INKplant project will develop an advanced 'toolbox' of technologies to enable 3D printing of tailor-made, biocompatible scaffolds that will facilitate tissue regeneration for diverse types of human tissue. The tools will include a portfolio of materials, 3D printing technologies, simulation and experimental evaluation. Show the project objective Hide the project objective Objective Improving the life quality of Europe’s increasingly elderly population is one of the most pressing challenges our society faces today. The need to treat age-related degenerative changes in e.g. articular joints or dental implants will boost the market opportunities for tissue regeneration products like biological scaffolds. State of the art 3D printing technologies can provide biocompatible implants with the right macroscopic shape to fit a patient-specific tissue defect. However, for a real functionality, there is a need for new biomaterials, technologies and processes that additionally allow the fabrication of a scaffold microstructure that induces tissue-specific regeneration. It is not possible to address the complexity in structure and properties of human tissues with a single material or fabrication technique. Besides, there are many types of tissue in the human body, each with their own internal structures and functions. INKplant vision is the fusion/combination of different biomaterials (6 different inks), high-resolution, high throughput additive manufacturing technologies already proved for industrial processes (ceramic sterolithography and 3D multimaterial inkjet printing), and advanced simulation and biological evaluation, to bring a new concept for the design and fabrication of biomimetic scaffolds (3D printed patient specific resorbable cell-free implants) which can address the complexity of the different tissue in the human body, demonstrated for 2 Use Cases. For a successful future translation, INKplant will consider all the relevant clinical adoption criteria already at the beginning of the development process. To address INKplant challenging objective the consortium includes the best expertise from the main areas of relevance to the project: biomaterials, 3D printing technology, tissue engineering, regulatory bodies and social humanities. Fields of science medical and health sciencesclinical medicineodontologydental implantologymedical and health sciencesmedical biotechnologytissue engineeringengineering and technologymechanical engineeringmanufacturing engineeringadditive manufacturingengineering and technologyindustrial biotechnologybiomaterialsmedical and health sciencesmedical biotechnologyimplants Keywords Biomaterials biomimetic scaffolds 3D multi-material inkjet printing Ceramic Additive Manufacturing High throughput Industrial process Hybid manufacturing ostheochondral dental ethics biological eval Programme(s) H2020-EU.2.1.2. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies Main Programme H2020-EU.2.1.3. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials Topic(s) NMBP-21-2020 - Biological scaffolds for tissue regeneration and repair (RIA) Call for proposal H2020-NMBP-TR-IND-2018-2020 See other projects for this call Sub call H2020-NMBP-TR-IND-2020-twostage Funding Scheme RIA - Research and Innovation action Coordinator PROFACTOR GMBH Net EU contribution € 842 580,35 Address Im stadtgut d1 4407 Steyr gleink Austria See on map Region Westösterreich Oberösterreich Steyr-Kirchdorf Activity type Other Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (18) Sort alphabetically Sort by Net EU contribution Expand all Collapse all STRATASYS LTD Israel Net EU contribution € 382 402,50 Address Holzman street 2 76124 Rehovot See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 LITHOZ GMBH Austria Net EU contribution € 406 200,00 Address Mollardgasse 85a 2 1 64-69 1060 Wien See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Ostösterreich Wien Wien Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 FLUIDINOVA SA Portugal Net EU contribution € 140 218,75 Address Rua de rosa jacome felgueiras 57 4475 188 Maia See on map Region Continente Norte Área Metropolitana do Porto Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 3D MATRIX EUROPE SAS France Net EU contribution € 139 660,00 Address 11 chemin des petites brosses 69300 Caluire et cuire See on map Region Auvergne-Rhône-Alpes Rhône-Alpes Rhône Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 LUXINERGY GMBH Austria Net EU contribution € 161 000,00 Address Peter tunner strasse 19 8700 Leoben See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Südösterreich Steiermark Östliche Obersteiermark Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ELKEM SILICONES FRANCE SAS France Net EU contribution € 273 643,75 Address Avenue georges pompidou 21 69003 Lyon See on map Region Auvergne-Rhône-Alpes Rhône-Alpes Rhône Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 TIGER Coatings Austria Net EU contribution € 435 982,50 Address Negrellistrasse 36 4600 Wels See on map Region Westösterreich Oberösterreich Linz-Wels Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSIDAD POLITECNICA DE MADRID Spain Net EU contribution € 216 125,00 Address Calle ramiro de maeztu 7 edificio rectorado 28040 Madrid See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITAT LINZ Austria Net EU contribution € 385 550,00 Address Altenberger strasse 69 4040 Linz See on map Region Westösterreich Oberösterreich Linz-Wels Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 KEPLER UNIVERSITATSKLINIKUM GMBH Austria Net EU contribution € 172 775,00 Address Krankenhausstrasse 7a 4020 Linz See on map Region Westösterreich Oberösterreich Linz-Wels Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 BIOMED CENTER INNOVATION GGMBH Germany Net EU contribution € 414 660,21 Address Ludwig-thoma-strasse 36c 95447 Bayreuth See on map Region Bayern Oberfranken Bayreuth, Kreisfreie Stadt Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 LUDWIG BOLTZMANN GESELLSCHAFT OSTERREICHISCHE VEREINIGUNG ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG Austria Net EU contribution € 303 933,75 Address Nussdorfer strasse 64/6 1090 Wien See on map Region Ostösterreich Wien Wien Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 MEDIZINISCHE UNIVERSITAET WIEN Austria Net EU contribution € 399 882,50 Address Spitalgasse 23 1090 Wien See on map Region Ostösterreich Wien Wien Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 CHARITE - UNIVERSITAETSMEDIZIN BERLIN Germany Net EU contribution € 383 506,25 Address Chariteplatz 1 10117 Berlin See on map Region Berlin Berlin Berlin Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 TRANSTISSUE TECHNOLOGIES GMBH Germany Net EU contribution € 340 528,75 Address Chariteplatz 1 virchowweg 11 10117 Berlin See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Berlin Berlin Berlin Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 BIOTECHNOLOGY INSTITUTE I MAS D Spain Net EU contribution € 270 080,00 Address Calle san antonio 15 5 01005 Vitoria See on map Region Noreste País Vasco Araba/Álava Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITAIR MEDISCH CENTRUM UTRECHT Netherlands Net EU contribution € 220 855,69 Address Heidelberglaan 100 3584 CX Utrecht See on map Region West-Nederland Utrecht Utrecht Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ASOCIACION ESPANOLA DE NORMALIZACION Spain Net EU contribution € 98 570,00 Address Calle genova 6 28004 Madrid See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Other Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00