Descripción del proyecto
Una ventanilla única para el diseño y la impresión 3D de armazones de tejidos biocompatibles
La ingeniería de tejidos y la regeneración de tejidos son temas de investigación que guardan una intensa relación y que han evolucionado enormemente de unos años a esta parte. Así como es preferible enseñar a una persona a pescar que darle un pescado, un implante que fomente la regeneración y la vida más allá de sí mismo es clave para la sostenibilidad y el impacto a largo plazo del tejido diseñado. El proyecto INKplant, financiado con fondos europeos, desarrollará una «caja de herramientas» avanzada de tecnologías para permitir la impresión tridimensional de armazones biocompatibles fabricados a medida y que facilitarán la regeneración de distintos tipos de tejidos humanos. Las herramientas incluirán una cartera de materiales, tecnologías de impresión 3D, simulación y evaluación experimental.
Objetivo
Improving the life quality of Europe’s increasingly elderly population is one of the most pressing challenges our society faces today. The need to treat age-related degenerative changes in e.g. articular joints or dental implants will boost the market opportunities for tissue regeneration products like biological scaffolds. State of the art 3D printing technologies can provide biocompatible implants with the right macroscopic shape to fit a patient-specific tissue defect. However, for a real functionality, there is a need for new biomaterials, technologies and processes that additionally allow the fabrication of a scaffold microstructure that induces tissue-specific regeneration. It is not possible to address the complexity in structure and properties of human tissues with a single material or fabrication technique. Besides, there are many types of tissue in the human body, each with their own internal structures and functions. INKplant vision is the fusion/combination of different biomaterials (6 different inks), high-resolution, high throughput additive manufacturing technologies already proved for industrial processes (ceramic sterolithography and 3D multimaterial inkjet printing), and advanced simulation and biological evaluation, to bring a new concept for the design and fabrication of biomimetic scaffolds (3D printed patient specific resorbable cell-free implants) which can address the complexity of the different tissue in the human body, demonstrated for 2 Use Cases. For a successful future translation, INKplant will consider all the relevant clinical adoption criteria already at the beginning of the development process. To address INKplant challenging objective the consortium includes the best expertise from the main areas of relevance to the project: biomaterials, 3D printing technology, tissue engineering, regulatory bodies and social humanities.
Ámbito científico
- medical and health sciencesclinical medicineodontologydental implantology
- medical and health sciencesmedical biotechnologytissue engineering
- engineering and technologymechanical engineeringmanufacturing engineeringadditive manufacturing
- engineering and technologyindustrial biotechnologybiomaterials
- medical and health sciencesmedical biotechnologyimplants
Palabras clave
Programa(s)
Convocatoria de propuestas
Consulte otros proyectos de esta convocatoriaConvocatoria de subcontratación
H2020-NMBP-TR-IND-2020-twostage
Régimen de financiación
RIA - Research and Innovation actionCoordinador
4407 STEYR GLEINK
Austria