Mechanistic Integration of vascular aND endocrine pathways for Subtyping Hypertension: an Innovative network approach for Future generation research Training

Información del proyecto

MINDSHIFT

Identificador del acuerdo de subvención: 954798

DOI

10.3030/954798

Proyecto cerrado

Fecha de la firma de la CE 18 Agosto 2020

Fecha de inicio 1 Enero 2021

Fecha de finalización 31 Marzo 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 4 124 385,00

Aportación de la UE

€ 4 124 385,00

Coordinado por

UNIVERSITEIT MAASTRICHT
Netherlands

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Other (4)

Media exposure of the MINDSHIFT Action as initiative for European School for Hypertension Research
ESR outreach activities

ESR outreach activities at e.g. secondary schools to create awareness for vascular health issues and research

Recruitment procedure installed

Recruitment procedure installed at all beneficiaries

Bioscientifica journal Special Issue

Publication of outcome/highlights of MINDSHIFT in Bioscientifica journal Special Issue

Websites, patent fillings, videos etc. (2)

Social media

MINDSHIFT social media pages installed by the ESR Committee

MINDSHIFT website

MINDSHIFT website including public course programme updates scheduled around general meetings Development website in M1 update until after the end of the programme M48

Publicaciones

Book chapters (2)

Chronic Kidney Disease and the Exposome of Ageing

Autores: Paul Shiels, Ngoc Tran, Jen McCavitt, Ognian Neytchev, Peter Stenvinkel
Publicado en: Subcellular Biochemistry, Biochemistry and Cell Biology of Ageing: Part IV, Clinical Science, 2023, Página(s) 79-94
Editor: Springer International Publishing
DOI: 10.1007/978-3-031-26576-1_5

MicroRNAs in aldosterone production and action

Autores: Scott M. MacKenzie, Lara A. Birch, Stelios Lamprou, Parisa Rezvanisanijouybari, May Fayad, Maria-Christina Zennaro, Eleanor Davies
Publicado en: Vitamins and Hormones, Adrenal Gland, 2024, Página(s) 137-163, ISBN 9780443194009
Editor: Elsevier
DOI: 10.1016/bs.vh.2023.07.001

Peer reviewed articles (29)

Endothelin antagonists and the quest for a new therapeutic option in resistant hypertension

Autores: Ralf Dechend; Christian Delles
Publicado en: The Lancet, 2022, ISSN 0140-6736
Editor: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(22)02181-x

Effect of rapid cooling, frozen storage, and thawing on the passive viscoelastic properties and structure of the rat aorta

Autores: Koen W.F. van der Laan, Koen D. Reesink, Sara Lambrichts, Nicole J.J.E. Bitsch, Laura van der Taelen, Sébastien Foulquier, Tammo Delhaas, Bart Spronck, Alessandro Giudici
Publicado en: Journal of Biomechanics, Edición 171, 2024, Página(s) 112190, ISSN 0021-9290
Editor: Elsevier BV
DOI: 10.1016/j.jbiomech.2024.112190

The Ultrasound Window Into Vascular Ageing: A Technology Review by the <scp>VascAgeNet COST</scp> Action

Autores: Elisabetta Bianchini, Andrea Guala, Spyretta Golemati, Jordi Alastruey, Rachel E. Climie, Kalliopi Dalakleidi, Martina Francesconi, Dieter Fuchs, Yvonne Hartman, Afrah E.F. Malik, Monika Makūnaitė, Konstantina S. Nikita, Chloe Park, Christopher J. A. Pugh, Agnė Šatrauskienė, Dimitrios Terentes‐Printizios, Alexandra Teynor, Dick Thijssen, Arno Schmidt‐Trucksäss, Jūratė Zupkauskienė, Pi
Publicado en: Journal of Ultrasound in Medicine, Edición 42, 2023, Página(s) 2183-2213, ISSN 0278-4297
Editor: American Institute for Ultrasound in Medicine
DOI: 10.1002/jum.16243

Ageing – Oxidative stress, PTMs and disease

Autores: Ebert T, Tran N, Schurgers L, Stenvinkel P, Shiels PG
Publicado en: Molecular Aspects of Medicine, 2022, ISSN 0098-2997
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.mam.2022.101099

Blood pressure measurement technique in clinical practice in the NHS Greater Glasgow and Clyde

Autores: Dellaneira Setjiadi, Colin Geddes, Christian Delles
Publicado en: Journal of Human Hypertension, 2024, ISSN 1476-5527
Editor: Springer Nature
DOI: 10.1038/s41371-024-00984-5

Radiomics Feature Extraction from Ultrasound B-Mode Images and Radio-Frequency Signals of the Carotid Arterial Wall: A Feasibility Study

Autores: Maryam Jadoon, Federica Poli, Pierre Boutouyrie, Hakim Khettab, Elisabetta Bianchini, Francesco Faita, Xavier Jouven, Jean Philippe Empana, Rosa Maria Bruno
Publicado en: Artery Research, Edición 31, 2025, ISSN 1876-4401
Editor: Springer Science and Business Media LLC
DOI: 10.1007/s44200-025-00076-w

Elevated blood pressure accelerates white matter brain aging among late middle-aged women: a Mendelian Randomization study in the UK Biobank

Autores: Li Feng, Zhenyao Ye, Chen Mo, Jingtao Wang, Song Liu, Si Gao, Hongjie Ke, Travis A. Canida, Yezhi Pan, Marleen M.J. van Greevenbroek, Alfons J.H.M. Houben, Kai Wang, Kathryn S. Hatch, Yizhou Ma, David K.Y. Lei, Chixiang Chen, Braxton D. Mitchell, L. Elliot Hong, Peter Kochunov, Shuo Chen, Tianzhou Ma
Publicado en: Journal of Hypertension, Edición 41, 2024, Página(s) 1811-1820, ISSN 0263-6352
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/hjh.0000000000003553

Central and local arterial stiffness in White Europeans compared to age-, sex-, and BMI-matched South Asians

Autores: Koen M. van der Sluijs, Jos Thannhauser, Iris M. Visser, P. M. Nabeel, Kiran V. Raj, Afrah E. F. Malik, Koen D. Reesink, Thijs M. H. Eijsvogels, Esmée A. Bakker, Prabhdeep Kaur, Jayaraj Joseph, Dick H. J. Thijssen
Publicado en: PLOS ONE, Edición 18, 2023, Página(s) e0290118, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0290118

Modulation of Calcium Signaling on Demand to Decipher the Molecular Mechanisms of Primary Aldosteronism

Autores: Bakhta Fedlaoui, Teresa Cosentino, Zeina R. Al Sayed, Rita Alexandre Coelho, Isabelle Giscos-Douriez, Nicolo Faedda, May Fayad, Jean-Sebastien Hulot, Chris Magnus, Scott M. Sternson, Simon Travers-Allard, Stephanie Baron, David Penton, Fabio L. Fernandes-Rosa, Maria-Christina Zennaro, Sheerazed Boulkroun
Publicado en: Hypertension, 2025, ISSN 0194-911X
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/hypertensionaha.124.23295

Type II Muscle Fiber Capillarization Is an Important Determinant of Post-Exercise Microvascular Perfusion in Older Adults

Autores: Milan W. Betz, Floris K. Hendriks, Alfons J.H.M. Houben, Mathias D.G. van den Eynde, Lex B. Verdijk, Luc J.C. van Loon, Tim Snijders
Publicado en: Gerontology, Edición 70, 2024, Página(s) 290-301, ISSN 0304-324X
Editor: S. Karger AG
DOI: 10.1159/000535831

Complement factors D and C3 cross-sectionally associate with arterial stiffness, but not independently of metabolic risk factors: The Maastricht Study

Autores: Shunxin Jin, Koen D. Reesink, Abraham A. Kroon, Bastiaan de Galan, Carla J.H. van der Kallen, Anke Wesselius, Casper G. Schalkwijk, Coen D.A. Stehouwer, Marleen M.J. van Greevenbroek
Publicado en: Journal of Hypertension, Edición 40, 2024, Página(s) 2161-2170, ISSN 0263-6352
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/hjh.0000000000003237

Pickering Syndrome: An Overlooked Renovascular Cause of Recurrent Heart Failure

Autores: Viola Sanga, Eleonora Bertoli, Filippo Crimì, Giulio Barbiero, Michele Battistel, Teresa Maria Seccia, Gian Paolo Rossi
Publicado en: Journal of the American Heart Association, Edición 12, 2024, ISSN 2047-9980
Editor: Wiley-Blackwell
DOI: 10.1161/jaha.123.030474

Finerenone protects against progression of kidney and cardiovascular damage in a model of type 1 diabetes through modulation of proinflammatory and osteogenic factors.

Autores: Sanz-Gómez M, Manzano-Lista FJ, Vega-Martín E, González-Moreno D, Alcalá M, Gil-Ortega M, Somoza B, Pizzamiglio C, Ruilope LM, Aránguez I, Kolkhof P, Kreutz R, Fernández-Alfonso MS
Publicado en: Biomedicine&Pharmacotherapy, Edición 168, 2023, ISSN 0753-3322
Editor: Elsevier Masson
DOI: 10.1016/j.biopha.2023.115661

Upregulation in Inflammation and Collagen Expression in Perirenal but Not in Mesenteric Adipose Tissue from Diabetic Munich Wistar Frömter Rats

Autores: Vega-Martín E, González-Moreno D, Sanz-Gómez M, Guzmán-Aguayo AK, Manzano-Lista FJ, Schulz A, Aránguez I, Kreutz R, Fernández-Alfonso MS
Publicado en: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242317008

Subclassification of obesity for precision prediction of cardiometabolic diseases

Autores: Daniel E. Coral, Femke Smit, Ali Farzaneh, Alexander Gieswinkel, Juan Fernandez Tajes, Thomas Sparsø, Carl Delfin, Pierre Bauvin, Kan Wang, Marinella Temprosa, Diederik De Cock, Jordi Blanch, José Manuel Fernández-Real, Rafael Ramos, M. Kamran Ikram, Maria F. Gomez, Maryam Kavousi, Marina Panova-Noeva, Philipp S. Wild, Carla van der Kallen, Michiel Adriaens, Marleen van Greevenbroek, Ilja Arts,
Publicado en: Nature Medicine, Edición 31, 2025, Página(s) 534-543, ISSN 1078-8956
Editor: Nature Publishing Group
DOI: 10.1038/s41591-024-03299-7

Role of Inflammatory and Proresolving Mediators in Endothelial Dysfunction

Autores: Ana M. Briones, Raquel Hernanz, Ana B. García‐Redondo, Cristina Rodríguez, Luis M. Blanco‐Colio, Almudena Val‐Blasco, María J. Alonso, Mercedes Salaices
Publicado en: Basic &amp; Clinical Pharmacology &amp; Toxicology, Edición 136, 2025, ISSN 1742-7835
Editor: Nordic Pharmacological Society
DOI: 10.1111/bcpt.70026

Nanobody-thioesterase chimeras to specifically target protein palmitoylation

Autores: Chien-Wen Kuo, Caglar Gök, Hannah Fulton, Eleanor Dickson-Murray, Samuel Adu, Emily K. Gallen, Sheon Mary, Alan D. Robertson, Fiona Jordan, Emma Dunning, William Mullen, Godfrey L. Smith, William Fuller
Publicado en: Nature Communications, Edición 16, 2025, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-025-56716-x

Specialized Pro-Resolving Lipid Mediators: New Therapeutic Approaches for Vascular Remodeling

Autores: Díaz Del Campo LS, Rodrigues-Díez R, Salaices M, Briones AM, García-Redondo AB
Publicado en: Int J Mol Sci, 2022, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23073592

Intracellular Calcium Dynamics in Primary Human Adrenocortical Cells Deciphered with a Novel Pipeline

Autores: Hala Ajjour, Giorgia Pallafacchina, Livia Lenzini, Brasilina Caroccia, Gian Paolo Rossi
Publicado en: High Blood Pressure &amp; Cardiovascular Prevention, Edición 31, 2024, Página(s) 299-308, ISSN 1179-1985
Editor: Springer
DOI: 10.1007/s40292-024-00641-5

Resolvin D2 Attenuates Cardiovascular Damage in Angiotensin II-Induced Hypertension

Autores: Lucia S. Díaz del Campo, Ana B. García-Redondo, Cristina Rodríguez, Carlos Zaragoza, Santiago Duro-Sánchez, Francesco Palmas, Angela de Benito-Bueno, Paula G. Socuéllamos, Diego A. Peraza, Raquel Rodrigues-Díez, Carmen Valenzuela, Jesmond Dalli, Mercedes Salaices, Ana M. Briones
Publicado en: Hypertension, Edición 80, 2024, Página(s) 84-96, ISSN 0194-911X
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/hypertensionaha.122.19448

The MAASWERP Study: An International, Comparative Case Study on Measuring Biomechanics of the Aged Murine Aorta

Autores: Cédric H.G. Neutel, Koen W.F. van der Laan, Callan D. Wesley, Dustin N. Krüger, Margarita G. Pencheva, Casper G. Schalkwijk, Guido R.Y. De Meyer, Wim Martinet, Tammo Delhaas, Koen D. Reesink, Alessandro Giudici, Pieter-Jan Guns, Bart Spronck
Publicado en: Pulse, Edición 13, 2025, Página(s) 1-10, ISSN 2235-8676
Editor: S. Karger AG
DOI: 10.1159/000542694

2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension

Autores: Giuseppe Mancia, Reinhold Kreutz, Mattias Brunström, Michel Burnier, Guido Grassi, Andrzej Januszewicz, Maria Lorenza Muiesan, Konstantinos Tsioufis, Enrico Agabiti-Rosei, Engi Abd Elhady Algharably, Michel Azizi, Athanase Benetos, Claudio Borghi, Jana Brguljan Hitij, Renata Cifkova, Antonio Coca, Veronique Cornelissen, J. Kennedy Cruickshank, Pedro G. Cunha, A.H. Jan Danser, Rosa Maria de Pinho,
Publicado en: Journal of Hypertension, Edición 41, 2024, Página(s) 1874-2071, ISSN 0263-6352
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/hjh.0000000000003480

El gen estimulado por interferón 15 (ISG15) modula el fenotipo de células musculares lisas vasculares y el remodelado vascular patológico

Autores: Julius Soudant, Raquel González-Blázquez, Abraham Merino, Constanza Ballesteros-Martínez, Raquel Rodrigues-Diez, Rosa Moreno-Carriles, J. Francisco Nistal, Susana Guerra, Juan Miguel Redondo, Mercedes Salaices, Ana M. Briones, Ana B. García-Redondo
Publicado en: Clínica e Investigación en Arteriosclerosis, 2025, Página(s) 500769, ISSN 0214-9168
Editor: Ediciones Doyma S.A.
DOI: 10.1016/j.arteri.2025.500769

Maternally inherited essential hypertension: adding further complexity to an already complex condition.

Autores: Delles, Christian
Publicado en: American Journal of Hypertension, Edición 1, 2022, ISSN 0895-7061
Editor: Oxford University Press
DOI: 10.1093/ajh/hpab133

Nailfold video-capillaroscopy in the study of cardiovascular disease: a systematic review

Autores: Matthew W.S. Lim, Dellaneira Setjiadi, Stephen J.H. Dobbin, Ninian N. Lang, Christian Delles, Paul J. Connelly
Publicado en: Blood Pressure Monitoring, 2024, ISSN 1359-5237
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/mbp.0000000000000624

Resolvin D2 prevents vascular remodeling, hypercontractility and endothelial dysfunction in obese hypertensive mice through modulation of vascular and proinflammatory factors

Autores: Raquel Rodrigues-Diez, Constanza Ballesteros-Martinez, Rosa María Moreno-Carriles, Francisco Nistal, Lucía S. Díaz del Campo, Victoria Cachofeiro, Jesmond Dalli, Ana B. García-Redondo, Juan M. Redondo, Mercedes Salaices, Ana M. Briones
Publicado en: Biomedicine &amp; Pharmacotherapy, Edición 174, 2024, Página(s) 116564, ISSN 0753-3322
Editor: Elsevier Masson
DOI: 10.1016/j.biopha.2024.116564

Circulating immune cells in cerebral small vessel disease: a systematic review

Autores: L. Van der Taelen, A. M. Briones, T. Unger, J. Staals, R. J. van Oostenbrugge, S. Foulquier
Publicado en: Biogerontology, Edición 26, 2025, ISSN 1389-5729
Editor: Kluwer Academic Publishers
DOI: 10.1007/s10522-025-10250-x

Capillary rarefaction: a missing link in renal and cardiovascular disease?

Autores: Floor M. E. G. Steegh, Anke A. Keijbeck, Patrick A. de Hoogt, Timo Rademakers, Alfons J. H. M. Houben, Koen D. Reesink, Coen D. A. Stehouwer, Mat J. A. P. Daemen, Carine J. Peutz-Kootstra
Publicado en: Angiogenesis, Edición 27, 2024, Página(s) 23-35, ISSN 0969-6970
Editor: Kluwer Academic Publishers
DOI: 10.1007/s10456-023-09883-8

Double CYP11B1/CYP11B2 Immunohistochemistry and Detection of KCNJ5 Mutations in Primary Aldosteronism

Autores: Brasilina Caroccia, Livia Lenzini, Giulio Ceolotto, Francesca Gioco, Andrea Benetti, Alessandra Giannella, Hala Ajjour, Francesca Galuppini, Gianmaria Pennelli, Teresa Maria Seccia, Celso Gomez-Sanchez, Gian Paolo Rossi
Publicado en: The Journal of Clinical Endocrinology &amp; Metabolism, Edición 109, 2025, Página(s) 2433-2443, ISSN 0021-972X
Editor: The Endocrine Society
DOI: 10.1210/clinem/dgae411