Mechanistic Integration of vascular aND endocrine pathways for Subtyping Hypertension: an Innovative network approach for Future generation research Training

Informazioni relative al progetto

MINDSHIFT

ID dell’accordo di sovvenzione: 954798

DOI

10.3030/954798

Progetto chiuso

Data della firma CE 18 Agosto 2020

Data di avvio 1 Gennaio 2021

Data di completamento 31 Marzo 2025

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 4 124 385,00

Contributo UE

€ 4 124 385,00

Coordinato da

UNIVERSITEIT MAASTRICHT
Netherlands

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Other (4)

Media exposure of the MINDSHIFT Action as initiative for European School for Hypertension Research
ESR outreach activities

ESR outreach activities at e.g. secondary schools to create awareness for vascular health issues and research

Recruitment procedure installed

Recruitment procedure installed at all beneficiaries

Bioscientifica journal Special Issue

Publication of outcome/highlights of MINDSHIFT in Bioscientifica journal Special Issue

Websites, patent fillings, videos etc. (2)

Social media

MINDSHIFT social media pages installed by the ESR Committee

MINDSHIFT website

MINDSHIFT website including public course programme updates scheduled around general meetings Development website in M1 update until after the end of the programme M48

Pubblicazioni

Book chapters (2)

Chronic Kidney Disease and the Exposome of Ageing

Autori: Paul Shiels, Ngoc Tran, Jen McCavitt, Ognian Neytchev, Peter Stenvinkel
Pubblicato in: Subcellular Biochemistry, Biochemistry and Cell Biology of Ageing: Part IV, Clinical Science, 2023, Pagina/e 79-94
Editore: Springer International Publishing
DOI: 10.1007/978-3-031-26576-1_5

MicroRNAs in aldosterone production and action

Autori: Scott M. MacKenzie, Lara A. Birch, Stelios Lamprou, Parisa Rezvanisanijouybari, May Fayad, Maria-Christina Zennaro, Eleanor Davies
Pubblicato in: Vitamins and Hormones, Adrenal Gland, 2024, Pagina/e 137-163, ISBN 9780443194009
Editore: Elsevier
DOI: 10.1016/bs.vh.2023.07.001

Peer reviewed articles (29)

Endothelin antagonists and the quest for a new therapeutic option in resistant hypertension

Autori: Ralf Dechend; Christian Delles
Pubblicato in: The Lancet, 2022, ISSN 0140-6736
Editore: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(22)02181-x

Effect of rapid cooling, frozen storage, and thawing on the passive viscoelastic properties and structure of the rat aorta

Autori: Koen W.F. van der Laan, Koen D. Reesink, Sara Lambrichts, Nicole J.J.E. Bitsch, Laura van der Taelen, Sébastien Foulquier, Tammo Delhaas, Bart Spronck, Alessandro Giudici
Pubblicato in: Journal of Biomechanics, Numero 171, 2024, Pagina/e 112190, ISSN 0021-9290
Editore: Elsevier BV
DOI: 10.1016/j.jbiomech.2024.112190

The Ultrasound Window Into Vascular Ageing: A Technology Review by the <scp>VascAgeNet COST</scp> Action

Autori: Elisabetta Bianchini, Andrea Guala, Spyretta Golemati, Jordi Alastruey, Rachel E. Climie, Kalliopi Dalakleidi, Martina Francesconi, Dieter Fuchs, Yvonne Hartman, Afrah E.F. Malik, Monika Makūnaitė, Konstantina S. Nikita, Chloe Park, Christopher J. A. Pugh, Agnė Šatrauskienė, Dimitrios Terentes‐Printizios, Alexandra Teynor, Dick Thijssen, Arno Schmidt‐Trucksäss, Jūratė Zupkauskienė, Pi
Pubblicato in: Journal of Ultrasound in Medicine, Numero 42, 2023, Pagina/e 2183-2213, ISSN 0278-4297
Editore: American Institute for Ultrasound in Medicine
DOI: 10.1002/jum.16243

Ageing – Oxidative stress, PTMs and disease

Autori: Ebert T, Tran N, Schurgers L, Stenvinkel P, Shiels PG
Pubblicato in: Molecular Aspects of Medicine, 2022, ISSN 0098-2997
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.mam.2022.101099

Blood pressure measurement technique in clinical practice in the NHS Greater Glasgow and Clyde

Autori: Dellaneira Setjiadi, Colin Geddes, Christian Delles
Pubblicato in: Journal of Human Hypertension, 2024, ISSN 1476-5527
Editore: Springer Nature
DOI: 10.1038/s41371-024-00984-5

Radiomics Feature Extraction from Ultrasound B-Mode Images and Radio-Frequency Signals of the Carotid Arterial Wall: A Feasibility Study

Autori: Maryam Jadoon, Federica Poli, Pierre Boutouyrie, Hakim Khettab, Elisabetta Bianchini, Francesco Faita, Xavier Jouven, Jean Philippe Empana, Rosa Maria Bruno
Pubblicato in: Artery Research, Numero 31, 2025, ISSN 1876-4401
Editore: Springer Science and Business Media LLC
DOI: 10.1007/s44200-025-00076-w

Elevated blood pressure accelerates white matter brain aging among late middle-aged women: a Mendelian Randomization study in the UK Biobank

Autori: Li Feng, Zhenyao Ye, Chen Mo, Jingtao Wang, Song Liu, Si Gao, Hongjie Ke, Travis A. Canida, Yezhi Pan, Marleen M.J. van Greevenbroek, Alfons J.H.M. Houben, Kai Wang, Kathryn S. Hatch, Yizhou Ma, David K.Y. Lei, Chixiang Chen, Braxton D. Mitchell, L. Elliot Hong, Peter Kochunov, Shuo Chen, Tianzhou Ma
Pubblicato in: Journal of Hypertension, Numero 41, 2024, Pagina/e 1811-1820, ISSN 0263-6352
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/hjh.0000000000003553

Central and local arterial stiffness in White Europeans compared to age-, sex-, and BMI-matched South Asians

Autori: Koen M. van der Sluijs, Jos Thannhauser, Iris M. Visser, P. M. Nabeel, Kiran V. Raj, Afrah E. F. Malik, Koen D. Reesink, Thijs M. H. Eijsvogels, Esmée A. Bakker, Prabhdeep Kaur, Jayaraj Joseph, Dick H. J. Thijssen
Pubblicato in: PLOS ONE, Numero 18, 2023, Pagina/e e0290118, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0290118

Modulation of Calcium Signaling on Demand to Decipher the Molecular Mechanisms of Primary Aldosteronism

Autori: Bakhta Fedlaoui, Teresa Cosentino, Zeina R. Al Sayed, Rita Alexandre Coelho, Isabelle Giscos-Douriez, Nicolo Faedda, May Fayad, Jean-Sebastien Hulot, Chris Magnus, Scott M. Sternson, Simon Travers-Allard, Stephanie Baron, David Penton, Fabio L. Fernandes-Rosa, Maria-Christina Zennaro, Sheerazed Boulkroun
Pubblicato in: Hypertension, 2025, ISSN 0194-911X
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/hypertensionaha.124.23295

Type II Muscle Fiber Capillarization Is an Important Determinant of Post-Exercise Microvascular Perfusion in Older Adults

Autori: Milan W. Betz, Floris K. Hendriks, Alfons J.H.M. Houben, Mathias D.G. van den Eynde, Lex B. Verdijk, Luc J.C. van Loon, Tim Snijders
Pubblicato in: Gerontology, Numero 70, 2024, Pagina/e 290-301, ISSN 0304-324X
Editore: S. Karger AG
DOI: 10.1159/000535831

Complement factors D and C3 cross-sectionally associate with arterial stiffness, but not independently of metabolic risk factors: The Maastricht Study

Autori: Shunxin Jin, Koen D. Reesink, Abraham A. Kroon, Bastiaan de Galan, Carla J.H. van der Kallen, Anke Wesselius, Casper G. Schalkwijk, Coen D.A. Stehouwer, Marleen M.J. van Greevenbroek
Pubblicato in: Journal of Hypertension, Numero 40, 2024, Pagina/e 2161-2170, ISSN 0263-6352
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/hjh.0000000000003237

Pickering Syndrome: An Overlooked Renovascular Cause of Recurrent Heart Failure

Autori: Viola Sanga, Eleonora Bertoli, Filippo Crimì, Giulio Barbiero, Michele Battistel, Teresa Maria Seccia, Gian Paolo Rossi
Pubblicato in: Journal of the American Heart Association, Numero 12, 2024, ISSN 2047-9980
Editore: Wiley-Blackwell
DOI: 10.1161/jaha.123.030474

Finerenone protects against progression of kidney and cardiovascular damage in a model of type 1 diabetes through modulation of proinflammatory and osteogenic factors.

Autori: Sanz-Gómez M, Manzano-Lista FJ, Vega-Martín E, González-Moreno D, Alcalá M, Gil-Ortega M, Somoza B, Pizzamiglio C, Ruilope LM, Aránguez I, Kolkhof P, Kreutz R, Fernández-Alfonso MS
Pubblicato in: Biomedicine&Pharmacotherapy, Numero 168, 2023, ISSN 0753-3322
Editore: Elsevier Masson
DOI: 10.1016/j.biopha.2023.115661

Upregulation in Inflammation and Collagen Expression in Perirenal but Not in Mesenteric Adipose Tissue from Diabetic Munich Wistar Frömter Rats

Autori: Vega-Martín E, González-Moreno D, Sanz-Gómez M, Guzmán-Aguayo AK, Manzano-Lista FJ, Schulz A, Aránguez I, Kreutz R, Fernández-Alfonso MS
Pubblicato in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242317008

Subclassification of obesity for precision prediction of cardiometabolic diseases

Autori: Daniel E. Coral, Femke Smit, Ali Farzaneh, Alexander Gieswinkel, Juan Fernandez Tajes, Thomas Sparsø, Carl Delfin, Pierre Bauvin, Kan Wang, Marinella Temprosa, Diederik De Cock, Jordi Blanch, José Manuel Fernández-Real, Rafael Ramos, M. Kamran Ikram, Maria F. Gomez, Maryam Kavousi, Marina Panova-Noeva, Philipp S. Wild, Carla van der Kallen, Michiel Adriaens, Marleen van Greevenbroek, Ilja Arts,
Pubblicato in: Nature Medicine, Numero 31, 2025, Pagina/e 534-543, ISSN 1078-8956
Editore: Nature Publishing Group
DOI: 10.1038/s41591-024-03299-7

Role of Inflammatory and Proresolving Mediators in Endothelial Dysfunction

Autori: Ana M. Briones, Raquel Hernanz, Ana B. García‐Redondo, Cristina Rodríguez, Luis M. Blanco‐Colio, Almudena Val‐Blasco, María J. Alonso, Mercedes Salaices
Pubblicato in: Basic &amp; Clinical Pharmacology &amp; Toxicology, Numero 136, 2025, ISSN 1742-7835
Editore: Nordic Pharmacological Society
DOI: 10.1111/bcpt.70026

Nanobody-thioesterase chimeras to specifically target protein palmitoylation

Autori: Chien-Wen Kuo, Caglar Gök, Hannah Fulton, Eleanor Dickson-Murray, Samuel Adu, Emily K. Gallen, Sheon Mary, Alan D. Robertson, Fiona Jordan, Emma Dunning, William Mullen, Godfrey L. Smith, William Fuller
Pubblicato in: Nature Communications, Numero 16, 2025, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-025-56716-x

Specialized Pro-Resolving Lipid Mediators: New Therapeutic Approaches for Vascular Remodeling

Autori: Díaz Del Campo LS, Rodrigues-Díez R, Salaices M, Briones AM, García-Redondo AB
Pubblicato in: Int J Mol Sci, 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23073592

Intracellular Calcium Dynamics in Primary Human Adrenocortical Cells Deciphered with a Novel Pipeline

Autori: Hala Ajjour, Giorgia Pallafacchina, Livia Lenzini, Brasilina Caroccia, Gian Paolo Rossi
Pubblicato in: High Blood Pressure &amp; Cardiovascular Prevention, Numero 31, 2024, Pagina/e 299-308, ISSN 1179-1985
Editore: Springer
DOI: 10.1007/s40292-024-00641-5

Resolvin D2 Attenuates Cardiovascular Damage in Angiotensin II-Induced Hypertension

Autori: Lucia S. Díaz del Campo, Ana B. García-Redondo, Cristina Rodríguez, Carlos Zaragoza, Santiago Duro-Sánchez, Francesco Palmas, Angela de Benito-Bueno, Paula G. Socuéllamos, Diego A. Peraza, Raquel Rodrigues-Díez, Carmen Valenzuela, Jesmond Dalli, Mercedes Salaices, Ana M. Briones
Pubblicato in: Hypertension, Numero 80, 2024, Pagina/e 84-96, ISSN 0194-911X
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/hypertensionaha.122.19448

The MAASWERP Study: An International, Comparative Case Study on Measuring Biomechanics of the Aged Murine Aorta

Autori: Cédric H.G. Neutel, Koen W.F. van der Laan, Callan D. Wesley, Dustin N. Krüger, Margarita G. Pencheva, Casper G. Schalkwijk, Guido R.Y. De Meyer, Wim Martinet, Tammo Delhaas, Koen D. Reesink, Alessandro Giudici, Pieter-Jan Guns, Bart Spronck
Pubblicato in: Pulse, Numero 13, 2025, Pagina/e 1-10, ISSN 2235-8676
Editore: S. Karger AG
DOI: 10.1159/000542694

2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension

Autori: Giuseppe Mancia, Reinhold Kreutz, Mattias Brunström, Michel Burnier, Guido Grassi, Andrzej Januszewicz, Maria Lorenza Muiesan, Konstantinos Tsioufis, Enrico Agabiti-Rosei, Engi Abd Elhady Algharably, Michel Azizi, Athanase Benetos, Claudio Borghi, Jana Brguljan Hitij, Renata Cifkova, Antonio Coca, Veronique Cornelissen, J. Kennedy Cruickshank, Pedro G. Cunha, A.H. Jan Danser, Rosa Maria de Pinho,
Pubblicato in: Journal of Hypertension, Numero 41, 2024, Pagina/e 1874-2071, ISSN 0263-6352
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/hjh.0000000000003480

El gen estimulado por interferón 15 (ISG15) modula el fenotipo de células musculares lisas vasculares y el remodelado vascular patológico

Autori: Julius Soudant, Raquel González-Blázquez, Abraham Merino, Constanza Ballesteros-Martínez, Raquel Rodrigues-Diez, Rosa Moreno-Carriles, J. Francisco Nistal, Susana Guerra, Juan Miguel Redondo, Mercedes Salaices, Ana M. Briones, Ana B. García-Redondo
Pubblicato in: Clínica e Investigación en Arteriosclerosis, 2025, Pagina/e 500769, ISSN 0214-9168
Editore: Ediciones Doyma S.A.
DOI: 10.1016/j.arteri.2025.500769

Maternally inherited essential hypertension: adding further complexity to an already complex condition.

Autori: Delles, Christian
Pubblicato in: American Journal of Hypertension, Numero 1, 2022, ISSN 0895-7061
Editore: Oxford University Press
DOI: 10.1093/ajh/hpab133

Nailfold video-capillaroscopy in the study of cardiovascular disease: a systematic review

Autori: Matthew W.S. Lim, Dellaneira Setjiadi, Stephen J.H. Dobbin, Ninian N. Lang, Christian Delles, Paul J. Connelly
Pubblicato in: Blood Pressure Monitoring, 2024, ISSN 1359-5237
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/mbp.0000000000000624

Resolvin D2 prevents vascular remodeling, hypercontractility and endothelial dysfunction in obese hypertensive mice through modulation of vascular and proinflammatory factors

Autori: Raquel Rodrigues-Diez, Constanza Ballesteros-Martinez, Rosa María Moreno-Carriles, Francisco Nistal, Lucía S. Díaz del Campo, Victoria Cachofeiro, Jesmond Dalli, Ana B. García-Redondo, Juan M. Redondo, Mercedes Salaices, Ana M. Briones
Pubblicato in: Biomedicine &amp; Pharmacotherapy, Numero 174, 2024, Pagina/e 116564, ISSN 0753-3322
Editore: Elsevier Masson
DOI: 10.1016/j.biopha.2024.116564

Circulating immune cells in cerebral small vessel disease: a systematic review

Autori: L. Van der Taelen, A. M. Briones, T. Unger, J. Staals, R. J. van Oostenbrugge, S. Foulquier
Pubblicato in: Biogerontology, Numero 26, 2025, ISSN 1389-5729
Editore: Kluwer Academic Publishers
DOI: 10.1007/s10522-025-10250-x

Capillary rarefaction: a missing link in renal and cardiovascular disease?

Autori: Floor M. E. G. Steegh, Anke A. Keijbeck, Patrick A. de Hoogt, Timo Rademakers, Alfons J. H. M. Houben, Koen D. Reesink, Coen D. A. Stehouwer, Mat J. A. P. Daemen, Carine J. Peutz-Kootstra
Pubblicato in: Angiogenesis, Numero 27, 2024, Pagina/e 23-35, ISSN 0969-6970
Editore: Kluwer Academic Publishers
DOI: 10.1007/s10456-023-09883-8

Double CYP11B1/CYP11B2 Immunohistochemistry and Detection of KCNJ5 Mutations in Primary Aldosteronism

Autori: Brasilina Caroccia, Livia Lenzini, Giulio Ceolotto, Francesca Gioco, Andrea Benetti, Alessandra Giannella, Hala Ajjour, Francesca Galuppini, Gianmaria Pennelli, Teresa Maria Seccia, Celso Gomez-Sanchez, Gian Paolo Rossi
Pubblicato in: The Journal of Clinical Endocrinology &amp; Metabolism, Numero 109, 2025, Pagina/e 2433-2443, ISSN 0021-972X
Editore: The Endocrine Society
DOI: 10.1210/clinem/dgae411