CORDIS - EU research results

Comorbidity of cHronic Pain and mood disorders: breaking the vicious cYcle

Project description

Fundamental insight into the association of chronic pain and mood disorders

Many patients suffer from more than one condition at the same time or successively, which are known as comorbidities. Chronic pain and mood disorders are among the most common and debilitating comorbidities that negatively impact patients in their everyday life. The EU-funded HaPpY project will bring together experts in the field to study chronic pain and mood disorders in an integrated manner. Researchers will undertake fundamental research, and through collaboration with clinical centres and companies, will ensure that the results are translated into clinical practice. Collectively, the project constitutes a concerted effort to break the vicious cycle that links pain and mood disorders.


The increasing number of patients with comorbidities poses an urgent need to improve their management. Among these comorbidities, chronic pain and mood disorders, two long-lasting disabling conditions that significantly reduce quality of life, could be cited first. Given the importance of this comorbidity, we believe that only research considering both pathologies in an integrative way can achieve the required insights into the underlying mechanisms that are necessary to identify novel diagnostic tools and treatment strategies. To respond to this health and societal emergency, we propose to establish a network of academic institutions and companies to provide 15 early stage researchers (ESRs) with a top quality international training programme.
The HaPpY network is comprised of higher education institutions with very well-established track records of scientific and academic excellence, and of research institutes with significant experience and cutting-edge approaches in fundamental research on mood disorders or/and pain. To ensure that discoveries in fundamental research can swiftly move toward clinical settings, to the benefit of patients and society, our consortium is enriched by clinical centres, companies and other non-academic partners. This consortium thus enables a unique research and training programme by combining and integrating the complementary strengths of each partner. HaPpY will thus provide ESRs with a broad scientific knowledge and foster their creative skills which will enable them to become leaders in either the academic or non-academic sectors.
We believe that only a coordinated programme aiming to train a new generation of talented and multidisciplinary researchers can succeed in our ambitious endeavor to break the vicious cycle linking pain and mood disorders.


Net EU contribution
€ 824 406,12
75794 Paris

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Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Total cost
€ 824 406,12

Participants (7)