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Comorbidity of cHronic Pain and mood disorders: breaking the vicious cYcle

Description du projet

Vision fondamentale de l’association de la douleur chronique et des troubles de l’humeur

Nombre de patients souffrent de plus d’une maladie à la fois ou successivement, un phénomène appelé «comorbidité». La douleur chronique et les troubles de l’humeur figurent parmi les comorbidités les plus courantes et les plus invalidantes ayant une incidence délétère sur la vie quotidienne des patients. Le projet HaPpY, financé par l’UE, rassemblera des experts du domaine pour étudier, de manière intégrée, la douleur chronique et les troubles de l’humeur. Les chercheurs mèneront des recherches fondamentales et, grâce à la collaboration avec des centres cliniques et des entreprises, s’assureront que les résultats seront traduits dans la pratique clinique. Collectivement, le projet constitue un effort concerté visant à briser le cercle vicieux qui lie la douleur aux troubles de l’humeur.

Objectif

The increasing number of patients with comorbidities poses an urgent need to improve their management. Among these comorbidities, chronic pain and mood disorders, two long-lasting disabling conditions that significantly reduce quality of life, could be cited first. Given the importance of this comorbidity, we believe that only research considering both pathologies in an integrative way can achieve the required insights into the underlying mechanisms that are necessary to identify novel diagnostic tools and treatment strategies. To respond to this health and societal emergency, we propose to establish a network of academic institutions and companies to provide 15 early stage researchers (ESRs) with a top quality international training programme.
The HaPpY network is comprised of higher education institutions with very well-established track records of scientific and academic excellence, and of research institutes with significant experience and cutting-edge approaches in fundamental research on mood disorders or/and pain. To ensure that discoveries in fundamental research can swiftly move toward clinical settings, to the benefit of patients and society, our consortium is enriched by clinical centres, companies and other non-academic partners. This consortium thus enables a unique research and training programme by combining and integrating the complementary strengths of each partner. HaPpY will thus provide ESRs with a broad scientific knowledge and foster their creative skills which will enable them to become leaders in either the academic or non-academic sectors.
We believe that only a coordinated programme aiming to train a new generation of talented and multidisciplinary researchers can succeed in our ambitious endeavor to break the vicious cycle linking pain and mood disorders.

Coordinateur

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Contribution nette de l'UE
€ 824 406,12
Adresse
RUE MICHEL ANGE 3
75794 Paris
France

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Région
Ile-de-France Ile-de-France Paris
Type d’activité
Research Organisations
Liens
Coût total
€ 824 406,12

Participants (7)